Dose of Alpha

What if the chain everyone calls a "ghost chain" or "a cult" is quietly becoming the closest thing crypto has to an actual working government? Dave (@Dave__Dionisio) joins Bryan Colligan and Eric Waisanen straight from the Cardano ecosystem — years auditing banks at the CFPB in D.C., then in deep with Input Output (formerly IOG), now working alongside Midgard, the Cardano layer-2 built by Anastasi...

What if the only thing keeping hundreds of millions in real-world assets off-chain is a four-day wait for a bank wire to clear? Mike Massari, Head of Partnerships at RedStone, joins Bryan Colligan and Eric Waisanen to break down what it takes to make RWAs work onchain — and why the fix has to live in the oracle. RedStone started as a price-feed oracle with a spotless track record, but secure feeds...

What if the most reliable 11% yield in crypto exists only because Wall Street still scores Bitcoin as negative capital? Kevin Li, co-founder and CEO of Saturn Credit, joins Bryan Colligan and Eric Waisanen to break down how MicroStrategy's digital credit is becoming the benchmark rate for onchain finance — and where it could break. Kevin ran the Digital Asset Treasury initiative at Artemis and has...

What if everything crypto teaches you about bootstrapping a blockchain — high yields, fat incentives, mercenary TVL — is exactly what guarantees its collapse? PaperImperium, economics lead at MegaETH, joins Bryan Colligan and Eric Waisanen to break down how you actually build a chain that lasts. Paper spent four years running the delegation portfolio at GFX Labs — a lifetime in crypto — through th...

Crypto showed up to Consensus Miami in a suit — and the culture didn't show up at all. Bryan and Eric catch up post-Miami: what's new, what's current, how it actually went, and the pivots they can feel coming. They debrief the whole circuit — Miami, ETH Denver, DAS New York — and the read is the same everywhere: crypto's growing up. Eric's now the youngest guy in rooms he used to be the oldest in....

What if the LP tokens already sitting in your wallet could back a loan, run a leveraged loop, and earn lending yield — without you selling a single token? Marcus Hardt of Balancer joins Bryan and Eric to break down how Balancer V3 turns liquidity positions into building blocks the rest of DeFi can actually use. Balancer pioneered weighted, multi-token pools — some running untouched for four years...

or simply the invisible hand? Michael Saylor just bought something other than Bitcoin — and that one move breaks the trade a whole lot of people were quietly front-running. Bryan and Eric's scheduled guest cancels, so they go live and unfiltered, and the whole conversation circles one question: who's the greater fool? This is Bryan Colligan and Eric Waisanen on decentralized finance, market maneuv...

What if the entire stablecoin economy is built on a monetary system that works in REVERSE of the dollar? Kory Hoang, CEO and co-founder of Stably, joins Bryan and Eric to break down a brand new taxonomy for stablecoins — and why credit expansion in DeFi actually SHRINKS the money supply instead of growing it. Kory was the fifth USD stablecoin issuer in the world. He and David launched on Binance b...

What if prediction markets aren't perps, aren't options, and aren't the gimmick everyone thinks they are? If you're still in your perps-maximalist bubble, this one's gonna sting. Prediction markets aren't perps. They're not options. They're a third thing — wisdom of crowds + insider trading + machine learning + AGI bait. Bryan calls it, "computational future projection." Eric calls it, "smart beta...

This was Dose of Alpha was streamed LIVE on YouTube ( https://www.youtube.com/live/V0zP7eYIYfk?si=uoPRDuMP0cLct4su ) on April 30, 2026. Bring RWAs onchain with us in 2026. Visit alphagrowth.io

This was Dose of Alpha was streamed LIVE on YouTube ( https://www.youtube.com/live/SOZgQbTHhAs?si=_E8PRjlum1F3Ood3) on April 4, 2026. Bring RWAs onchain with us in 2026. Visit alphagrowth.io

The S&P 500 didn't tokenize. They didn't lend. They went straight to Hyperliquid — and made $2.5 million on a Monday. In Episode 7 of Dose of Alpha , Eric Waisanen breaks down what he actually learned at the Digital Asset Summit in New York: TradFi isn't here to validate crypto. They're here to win. And they're playing a completely different game than anyone expected. Eric and Bryan unpack the mec...

What if your AI agent could out-trade institutional desks — from your laptop? In Episode 5 of Dose of Alpha, Bryan Colligan sits down with Taariq Lewis, founder of Seren DB and a crypto OG since 2013, to break down the "Open Claw" world: a future where locally-running AI agents autonomously research, execute, and report on trades — no middlemen, no managed accounts, no waiting on a fund. They cove...

Join Alpha Growth CEO Bryan Colligan and DeFi Strategist Eric Waisanen for Ep. 4: Steer & Automation , as Alpha Growth interviews Steer Protocol on the newest podcast episode of: "Dose of Alpha." Real-time intel from the DeFi front lines. Colligan and Waisanen share unfiltered perspectives exploring decentralized finance, market maneuvers, TradFi convergence, and the enduring importance of crypto...

Join Alpha Growth CEO Bryan Colligan and DeFi Strategist Eric Waisanen for Ep. 3: Money Markets vs. CDPs of Alpha Growth's newest podcast:  "Dose of Alpha." Get real-time intel from the DeFi front lines. Colligan and Waisanen share unfiltered perspectives exploring decentralized finance, market maneuvers, TradFi convergence, and the enduring importance of crypto in today's political and economic l...

Alpha Growth CEO Bryan Colligan and DeFi Strategist Eric Waisanen get deep into the weeds with Alpha Growth's latest podcast: Dose of Alpha- Episode #2: Risk: Are You A Gambler or Investor? In each episode Colligan and Waisanen share unfiltered perspectives exploring decentralized finance, market maneuvers, TradFi convergence, and the enduring importance of crypto in today's political and economic...

Join CEO Bryan Colligan and DeFi Strategist Eric Waisanen for the premiere episode of Alpha Growth's newest podcast: "Dose of Alpha." Where you'll hear real-time intel from the DeFi front lines. Colligan and Waisanen share unfiltered perspectives exploring decentralized finance, market maneuvers, TradFi convergence, and the enduring importance of crypto in today's political and economic landscape....