Panther Labs

Detection at Scale

The Detection at Scale Podcast is dedicated to helping security practitioners and their teams succeed at managing and responding to threats at a modern, cloud scale. Hosted by Jack Naglieri, Founder and CTO at Panther, every episode is focused on actionable takeaways to help you get ahead of the curve and prepare for the trends and technologies shaping the future.

Author

Panther Labs

Category

Technology

Latest episode

May 12, 2026

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Episodes

Closing The Alert vs. Closing The Loop: How AI Is Reinventing the SOC 12.05.2026

This week is a special episode of the Detection at Scale podcast. I’m usually the one asking the questions, but this time I’m in the guest chair, hosted by Julian Giuca, Panther’s Chief Product Officer. Our conversation covers the journey of building Panther’s AI SOC platform: From the evolution of the SOC from human-led to AI-enabled, the shifts of the last few years that took LLMs from “autocomp...

Google's Michael Sinno on Autonomous Detection at 7 Trillion Logs Per Day 24.02.2026

What does it actually take to automate security operations when you're processing 7 trillion log lines daily and a single missed threat could compromise billions of users? Michael Sinno , Director of Detection & Response at Google , explains how his team handles this with less than 1% requiring human intervention through strategic AI implementation. He explores Google's methodical appr...

Block's CISO James Nettesheim on How 40% of Their Detections Are Now Written with AI 10.02.2026

What if the real risk isn't adopting AI agents, but refusing to? James Nettesheim , CISO & Head of Enterprise Technology at Block , argues that principled risk-taking beats playing it safe. James shares Block's journey co-designing the Model Context Protocol with Anthropic and building Goose, their open-source general-purpose agent that enables anyone in the company to write security detection...

Compass' Ryan Glynn on Why LLMs Shouldn't Make Security Decisions — But Should Power Them 27.01.2026

Ryan Glynn , Staff Security Engineer at Compass , has a practical AI implementation strategy for security operations. His team built machine learning models that removed 95% of on-call burden from phishing triage by combining traditional ML techniques with LLM-powered semantic understanding.  He also explores where AI agents excel versus where deterministic approaches still win, why tuning detecti...

Veeva Systems' Mike Vetri on Building Threat Operations Teams and AI-Powered Investigations 13.01.2026

Mike Vetri , Sr. Director of Security Operations at Veeva Systems , reflects on transforming SOC investigations through AI-powered data aggregation and building threat operations teams with the analytical mindset required for proactive defense. Mike introduces the C3 Matrix framework for prioritizing security efforts across centers of gravity, crown jewels, and capability enablers, and explains th...

Trustpilot's Gary Hunter on Structuring Security Knowledge for AI Success 23.12.2025

Gary Hunter , Head of Security Operations at Trustpilot , built a security team from scratch at a company synonymous with trust. Gary shares how his ten-person team leverages AI agents across alert triage, multimodal brand protection, and incident response.  He explores why he and his team treat AI agents like interns with codified guardrails, why competitive prompt testing reveals the best approa...

Vjaceslavs Klimovs on Why 40% of Security Work Lacks Threat Models 09.12.2025

Vjaceslavs Klimovs , Distinguished Engineer at CoreWeave , reflects on building security programs in AI infrastructure companies operating at massive scale. He explores how security observability must be the foundation of any program, how to ensure all security work connects to concrete threat models, and why AI agents will make previously tolerable security gaps completely unacceptable.  Vjacesla...

GreenSky's Ken Bowles on Auditing Controls before They Silently Fail 25.11.2025

Over his 15-year journey through healthcare and financial services security, Ken Bowles , now Director of Security Operations at GreenSky , has collected a plethora of practical strategies for prioritizing crown jewels, managing cloud over-permissions, and building SOCs that scale effectively. He reflects on transforming security operations through AI and intelligent automation and discusses how A...

FanDuel's Tyler Martin on the Bronze-Silver-Gold Path to Autonomous Security Triage 11.11.2025

Tyler Martin , Senior Director of Enterprise Security Engineering & Operations at FanDuel , reflects on revolutionizing security operations by replacing traditional analyst tiers with security engineers supported by custom AI agents. Tyler shares the architecture behind SAGE, FanDuel's phishing automation system, and explains how his team progressed from human-in-the-loop validation to fully a...

Live Oak Bank's George Werbacher on AI As SecOps' Single Pane of Glass 28.10.2025

George Werbacher , Head of Security Operations at Live Oak Bank , reviews the practical realities of implementing AI agents in security operations, sharing his journey from exploring tools like Cursor and Claude Code to building custom agents in-house. He also reflects on the challenges of moving from local development to production-ready systems with proper durability and retry logic. The convers...

Ochsner Health's Andrew Casazza on When AI Becomes the Hammer Looking for Nails 14.10.2025

Andrew Casazza , AVP of Cyber Security Operations at Ochsner Health , explores how healthcare organizations navigate FDA-approved medical devices running on legacy operating systems, implement AI-powered security tools while maintaining HIPAA compliance, and respond to threats that now move from initial compromise to malicious action in seconds rather than hours.  Andrew gives Jack his insights on...

Cisco Meraki's Stephen Gubenia on How to Crawl-Walk-Run to AI-Powered SecOps 23.09.2025

Stephen Gubenia , Head of Detection Engineering for Threat Response for Cisco Meraki , shares his evolution from managing overwhelming alert volumes as a one-person security team to architecting sophisticated automated systems that handle everything from enrichment to containment.  Stephen discusses the organizational changes needed for successful AI adoption, including top-down buy-in and proper...

Databricks' Dave Herrald on Building SOCs with Data Lakes & Focused AI Agents 04.09.2025

Dave Herrald , Global Head of Cybersecurity GTM at Databricks , tells Jack about transforming security operations through modern data lake architectures and strategic AI implementation. He discusses the practical benefits of separating storage from compute, giving security teams direct control over data retention while maintaining operational flexibility. The conversation explores how organization...

Tines' Matt Muller on AI-Assisted Security Operations and Modernizing the SOC 21.08.2025

Matt Muller , Field CISO at Tines , knows all about revolutionizing security operations through strategic AI integration and intelligent automation. In his conversation with Jack , Matt explores how traditional SOC models create problematic feedback loops where junior analysts make critical decisions while senior practitioners handle escalations, limiting learning and growth opportunities.  Instea...

Illumio's Erik Bloch on Getting Security Fundamentals Right Before Adding AI 15.07.2025

In this episode of Detection at Scale, Jack speaks with Erik Bloch , VP of Security, Illumio , about why most security operations teams aren't ready for AI tools and what fundamental processes must be in place first. Erik challenges the industry's obsession with new technologies, sharing stories from his experience transforming underperforming security teams at major companies like Cisco, Salesfor...

SANS's John Hubbard on Future-Proofing SOC Analysts in the Age of AI 01.07.2025

Drawing from his experience building enterprise SOCs and teaching thousands of security professionals, John Hubbard , Cyber Defense Curriculum Lead at SANS Institute and host of the Blueprint podcast, tells Jack about how AI is revolutionizing security operations centers, including balancing AI automation with fundamental analyst skills. They also explore practical AI applications in alert context...

Airwallex's Elliot Colquhoun on Big Bet Security Investments That Pay Off 17.06.2025

Elliot Colquhoun , VP of Information Security + IT at Airwallex , has built what might be the most AI-native security program in fintech, protecting 1,800 employees with just 9 security engineers by building systems that think like the best security engineers. His approach to contextualizing every security alert with institutional knowledge offers a blueprint for how security teams can scale expon...

1Password's Jacob DePriest on Balancing Human Intuition and AI in Cybersecurity 22.04.2025

In this episode of Detection at Scale, Jack speaks with Jacob DePriest , VP of Security/CISO at 1Password , who shares insights from his 15-year journey from the NSA to leading security at GitHub through his current role. Jacob discusses his framework for assessing security programs with fresh eyes, emphasizing business objectives first, then addressing risks, and finally implementing the right se...

Two Candlesticks' Matthew Martin on Leveraging AI for Resource-Constrained Security Operations 08.04.2025

In this episode of Detection at Scale, Matthew Martin , Founder of Two Candlesticks , shares practical approaches for implementing AI in security operations, particularly for smaller companies and those in emerging markets. Matthew explains how AI chatbots can save analysts up to 45 minutes per incident by automating initial information gathering and ticket creation. Matthew’s conversation with Ja...

Pangea’s Oliver Friedrichs on Building Guardrails for the New AI Security Frontier 25.03.2025

The security automation landscape is undergoing a revolutionary transformation as AI reasoning capabilities replace traditional rule-based playbooks. In this episode of Detection at Scale, Oliver Friedrichs , Founder & CEO of Pangea , helps Jack unpack how this shift democratizes advanced threat detection beyond Fortune 500 companies while simultaneously introducing an alarming new attack surf...

Panther's Matt Jezorek on Simplifying Security and Balancing Human Intuition with AI 11.03.2025

In this special episode of Detection at Scale, Jack welcomes back Matt Jezorek , Panther's new CISO, for an insightful conversation about effective security strategies. Drawing from his experience scaling Amazon's security operations and leading teams at Dropbox, Matt advocates for a simplified approach focused on three core pillars: identity protection, vulnerability management, and detection/res...

Rabbit’s Matthew Domko on Using Engineering-First Security to Build Modern Detection Programs 25.02.2025

Managing security for a device that can autonomously interact with third-party services presents unique orchestration challenges that go beyond traditional IoT security models. In this episode of Detection at Scale, Matthew Domko , Head of Security at Rabbit , gives Jack an in-depth look at building security programs for AI-powered hardware at scale.   He details how his team achieved 100% infrast...

Salesforce's Mor Levi on Transforming Security Operations with AI Agents 11.02.2025

What does AI in security operations actually look like at scale? In this episode of Detection at Scale, Mor Levi , VP of Detection, Analysis, & Response at Salesforce , shares her team's hands-on experience with Agent Force — from achieving 90% automation in initial case triage to setting ambitious goals for full automation.  Her conversation with Jack goes deep into the practical realities: i...

Outreach’s Brandon Kovitz on Balancing Human Intuition and AI in Cyber Defense 27.11.2024

In this episode of Detection at Scale, Jack speaks to Brandon Kovitz , Senior Manager of Detection & Response at Outreach , shares his insights on the evolving landscape of cybersecurity. He discusses the critical role of generative AI in enhancing detection and response capabilities, emphasizing the importance of understanding data to maximize security tools' effectiveness.    Brandon also hi...

Rootly’s JJ Tang on Transforming Incident Management Culture 14.11.2024

In this episode of Detection at Scale, Jack speaks to JJ Tang , CEO and Co-founder of Rootly , about revolutionizing incident management in tech organizations. JJ shares his journey from practitioner to founder and emphasizes the importance of viewing incident management as a cultural and collaborative effort rather than just a tooling issue.    JJ touches on breaking down silos between security a...

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