Decera Clinical Education Infectious Disease Podcast

In this episode, Dalilah Restrepo, MD, discusses expert guidance on vaccination for the prevention of shingles complications in the COVID-19 era. Contributor: Dalilah Restrepo, MD Infectious Diseases Specialist Fountain Valley Hospital Fountain Valley, California Using a case study and the latest expert guidance, this podcast covers topics such as:  Expert guidance on maintenance of routine vaccin...

In this episode, William R. Short, MD, MPH, AAHIVS, explores recommendations and data on strategies to address suboptimal CD4+ cell count response in people with HIV on suppressive ART. Listen as he gives his perspectives on: The consequences of suboptimal CD4+ cell count response ART intensification ART switch strategies with data from the SPIRAL study Data on the addition of interleukin-2 from t...

In this episode, Prof Ashley Brown, BSc, MD, FRCP, and Ahmed M. Elsharkawy, PhD, FRCP(UK), discuss key racial inequities of care that lead to undertreatment for migrant populations and other racial minorities globally with or at risk for hepatitis C. Topics include: HCV Burden and Care Disparities in Specific Populations Genotypes and Length of Infection in Ethnic Minorities Primary Care Education...

In this episode, Fidelia Bernice, PharmD, and Aadia I. Rana, MD, share insights on HIV ART safety and tolerability including recent data on nephrotoxicity and the use of NRTI-sparing regimens with discussion of the GEMINI-1 and -2 studies of DTG/3TC and the SWORD-1 and -2 studies of DTG/RPV, and safety with long-acting injectables with specific discussion of the ATLAS and FLAIR studies of LA CAB p...

In this episode, Tracy Zivin-Tutela, MD, discusses expert guidance on vaccination against shingles. Tracy Zivin-Tutela, MD Infectious Diseases Specialist Department of Infectious Diseases Fountain Valley Regional Hospital Los Alamitos Medical Center Fountain Valley, California Using a case study and the latest expert guidance, this podcast covers topics such as:  Counseling patients on benefits an...

In this episode, William R. Short, MD, MPH, AAHIVS, explores recommendations and data on switching to 2-drug single-tablet ART regimens. Listen as he gives his perspectives on: Indications for the available 2-drug single-tablet regimens: DTG/RPV and DTG/3TC The SWORD-1 and SWORD-2 studies evaluating switching to DTG/RPV in virologically suppressed patients Real-world experience with switching to D...

In this episode, Gregory Dore, MBBS, PhD, FRACP, MPH, and Stacey Trooskin, MD, PhD, MPH, share lessons learned in the care of patients with HCV infection during the COVID-19 pandemic, including: Telehealth Treatment of PWID TEMPO pilot study MINMON study Presenters: Gregory Dore, MBBS, PhD, FRACP, MPH Professor, Head Viral Hepatitis Clinical Research Program Kirby Institute University of New South...

In this episode, hepatologist Giada Sebastiani, MD, discusses why the presence of obesity, metabolic syndrome, persistent elevation of ALT, or exposure to dideoxynucleoside analogues can trigger an evaluation for NAFLD and NASH, particularly in our aging population of patients with HIV with topics including: Metabolic factors   HIV-related factors Which patients with HIV are at risk Presenter: Gia...

In this episode from the series “Key Decisions in HIV Care,” Milena Murray, PharmD, MSc, BCIDP, AAHIVP, and Jonah Musa, MBBS, MSCI, PhD, discuss important considerations for ART use in pregnancy, including DHHS and WHO guideline recommendations and data supporting recommended ART regimen options in pregnancy from IMPAACT 2010, Tsepamo, and DoLPHIN-2. They also discuss pharmacokinetic consideration...

In this episode, Renslow Sherer, MD, discusses new COVID-19 data from IDWeek 2021, including: Prevention of COVID-19 ChAdOx1 nCoV-19 Ad26.COV2.S Tixagevimab plus cilgavimab Outpatients with COVID-19 Remdesivir IV Molnupiravir Hospitalized patients with COVID-19 Baricitinib Lenzilumab Casirivimab plus imdevimab Long-term COVID-19 outcomes Sustained recovery Presenter: Renslow Sherer, MD Director In...

In this episode, Oni Blackstock, MD, MHS, and Nina T. Harawa, PhD, MPH, discuss racial disparities in COVID-19 outcomes, including: Background on healthcare inequities among BIPOC COVID-19 racial disparities and the healthcare inequities driving them Overcoming barriers to optimal COVID-19 care among BIPOC Addressing concerns about COVID-19 vaccination   Motivational interviewing principles and th...

In this episode, Nicholas Chamberlain, MD, provides an overview of the different antiretroviral drug formulations and dosing strategies in various stages of clinical development for long-acting HIV PrEP—advances that collectively offer the potential for highly individualized approaches to HIV biomedical prevention. Presenter: Nicholas Chamberlain, MD Medical Director AHF Healthcare Center – Atlant...

In episode 1 of an ongoing series of conversations between a physician and patient, Stacey Trooskin, MD, PhD, MPH, and patient advocate Brother Dan Palmer discuss approaches to improve access to HCV therapy. The conversation focuses on how barriers to care affected Dan’s health after his hepatitis C diagnosis and the strategies he employed to overcome them. Presenter: Stacey Trooskin, MD, PhD, MPH...

In this podcast episode, Paul E. Sax, MD, and Renslow Sherer, MD, discuss the clinical significance of new data on the prevention and treatment of COVID-19, including: COVID-19 in immunocompromised hosts Prime-Boost Strategy for COVID-19 vaccination COVID-19 surge effects Monoclonal antibody therapy for prevention and treatment Remdesivir update Repurposed drug, fluvoxamine What does the future of...

In this episode, Milena Murray, PharmD, MSc, BCIDP, AAHIVP, explores recommendations and data to support the management of missed CAB plus RPV injections. Listen as she gives her perspectives on: Prescribing information recommendations for managing missed injections of CAB plus RPV Pharmacokinetic modeling data to support management strategies for missed injections Data from the ATLAS and FLAIR st...

In this episode, Milena Murray, PharmD, MSc, BCIDP, AAHIVP, explores recommendations and data on maternal weight gain associated with ART use in pregnancy. Listen as she gives her perspectives on: IMPAACT 2010 data on maternal weight gain with DTG + FTC/TAF vs DTG + FTC/TDF vs EFV/FTC/TDF SMARTT study data on gestational weight gain by ART class Tsepamo Surveillance study data on maternal weight a...

In this episode, Darcy Wooten, MD, discusses new HIV data from IDWeek 2021, including: A rapid test-and-treat program to start DTG/3TC in patients newly diagnosed with HIV (STAT) Efficacy when switching from 3-drug to 4-drug TAF-based regimens to DTG/3TC (TANGO) Virologic outcomes with 2-drug vs 3-drug ART regimens (Trio Health HIV Network Study) Metabolic complications in treatment-naive patients...

During this episode, Lynora Saxinger, MD, FRCPC, CTropMed, updates listeners on the latest Emergency Use Authorizations and guideline recommendations for optimal clinical management of COVID-19. Gain practical insights on patient identification, risk stratification, and treatment. Key points include: Treatment of COVID-19 can be broken into antiviral and immune-modulating therapies Each agent shou...

In this episode from the series “Key Decisions in HIV Care,” Jason Halperin, MD, MPH, and Jürgen K. Rockstroh, MD, discuss important considerations in the rapid initiation of ART, including guideline recommendations and data supporting recommended ART regimen options for rapid initiation and emerging data for the 2-drug regimen dolutegravir/lamivudine for rapid start from the STAT study. Following...

In this episode, Milena Murray, PharmD, MSc, BCIDP, AAHIVP, explores the data to support the use of tenofovir alafenamide in pregnancy. Listen as she gives her perspectives on: DHHS guideline recommendations for the use of TAF in pregnancy Pharmacokinetic data to support adequate TAF concentrations throughout pregnancy Available antiretroviral pregnancy registry information on the use of TAF in pr...

In this episode, Tracy Zivin-Tutela, MD, discusses factors that put your patients at risk for shingles and its complications. Tracy Zivin-Tutela, MD Infectious Diseases Specialist Department of Infectious Diseases Fountain Valley Regional Hospital Los Alamitos Medical Center Fountain Valley, California Using a case study and the latest data, this podcast covers topics such as:  Pathophysiology and...

In this episode, Jason Halperin, MD, MPH, explores the data to support rapid ART initiation in adolescent patients. Listen as he gives his perspectives on: DHHS and IAS-USA guidelines for rapid initiation and specific recommendations for adolescents and young adults CrescentCare data comparing the virologic outcomes for patients 18-24 years of age compared with those aged 25 years or older Data to...

In this episode, Jason Halperin, MD, MPH, explores the data to support rapid ART initiation in patients with OUD. Listen as he gives his perspectives on: DHHS guidelines for rapid initiation of ART and specific recommendations for patients with substance use disorders SAMSHA recommendations for the treatment of OUD Medications that are recommended for the treatment of OUD, including drug–drug inte...

In this episode, Colleen Kelley, MD, MPH, discusseskey features and available safety and efficacy data on investigational long-acting HIV pre-exposure prophylaxis strategies that are in late stages of clinical development. Presenter: Colleen Kelley, MD, MPH Atlanta, Georgia  Colleen Kelley, MD, MPH, has disclosed that she has received funds for research support from Gilead Sciences, Moderna, Novav...

In this second of 2 episodes, Shobha Swaminathan, MD, and Eric S. Daar, MD, review key data influencing their practice following the IAS 2021 Conference, including data on investigational antiretroviral agents, lenacapavir and islatravir, and alternative dosing of BPaL for MDR-TB.   This episode includes discussion of: An extension of FLAIR, demonstrating virologic efficacy and safety of long-acti...