Decera Clinical Education Infectious Disease Podcast

In this episode, Robert G. Gish, MD, and Pietro Lampertico, MD, PhD, share lessons learned in the care of patients coinfected with hepatitis B virus and hepatitis delta virus (HDV), including: Burden of HDV infection Chronic HDV infection and comorbidities Impact of COVID-19 on care of patients with chronic hepatitis B Screening for HDV and which assays to use Screening for viral hepatitis at a CO...

In this episode from the series “Key Decisions in HIV Care,” Jonathan Appelbaum, MD, FACP, AAHIVS, and Jens D. Lundgren, MD, DMSc, discuss important considerations for antiretroviral therapy (ART) use in older patients with renal and hepatic impairment. European AIDS Clinical Society guideline screening recommendations for kidney disease in people with HIV Antiretroviral dose adjustment recommenda...

In this episode, Jürgen K. Rockstroh, MD, and Giada Sebastiani, MD, discuss key strategies to appropriately screen for, identify, and manage nonalcoholic steatohepatitis in persons with HIV. They also answer pressing questions from healthcare professionals. Presenters:  Jürgen K. Rockstroh, MD Professor of Medicine University Hospital Bonn Department of Medicine I Bonn, Germany Giada Sebastiani, M...

In this episode, Jürgen K. Rockstroh, MD, discusses his recommended approach for diagnosing nonalcoholic steatohepatitis in patients with HIV, the value of noninvasive diagnostic tests such as serum biomarkers and elastography, and how timely nonalcoholic fatty liver disease assessment and metabolic risk factor determination can result in early interventions. Presenter: Jürgen K. Rockstroh, MD Pro...

In this episode, John D. Baxter, MD, explores recommendations and data on the use of proviral DNA genotyping to inform antiretroviral therapy (ART) choice for patients who are treatment experienced. Listen as he gives his perspectives on: US Department of Health and Human Services guideline recommendations on the use of proviral DNA genotyping US Department of Health and Human Services guideline r...

In this episode, Rageshri Dhairyawan, MBBS, BSc, FRCP, DipGUM, DFSRH, DipHIV, and Solange L. Baptiste, ScM, discuss the burden of HIV among BIPOC and migrant communities and key strategies to reduce racial disparities in HIV care globally: Disproportionate impact of HIV among BIPOC communities and migrant populations globally Barriers to HIV testing, prevention, and treatment services among BIPOC...

In this episode, John D. Baxter, MD, explores recommendations and data on choosing antiretroviral therapy with transmitted drug resistance. Listen as he gives his perspectives on: Initial response to antiretroviral therapy during primary HIV infection with baseline resistance Data from the START study on treatment-naive patients with transmitted drug resistance by region and drug class Recommendat...

The SARS-CoV-2 omicron variant has affected which of our COVID-19 treatment strategies are currently effective, with some expected to maintain their efficacy and some expected to lose their efficacy. In this episode, Arthur Kim, MD, discusses the effects of the SARS-CoV-2 omicron variant on many of the COVID-19 approved, authorized, and investigational treatment options, including: Direct-acting,...

In this episode, Samantha V. Hill, MD, MPH, and David Malebranche, MD, MPH, examine key facilitators to tackling racial inequities in HIV care, including: Barriers to HIV testing, prevention, and treatment services in BIPOC communities and migrant populations Facilitators to HIV testing, prevention, and treatment services in BIPOC communities and migrant populations Strategies to overcome health s...

In this episode from the series “Key Decisions in HIV Care,” Daria Podlekareva, MD, PhD, and Mark S. Sulkowski, MD, discuss important considerations for ART use in patients with coinfections, including: DHHS testing and treatment recommendations for HBV in patients with HIV Data suggesting that tenofovir alone may not suppress HBV in all PWH Data from NA-ACCORD showing that incomplete HBV DNA supp...

In this episode, Karen Ha, MD, explores recommendations and data on the role of PIs in current practice. Listen as she gives her perspectives on: DHHS guideline recommendations on the use of PI-based ART Data from the DIAMOND study on the use of boosted DRV for rapid initiation Data from the EARNEST and NADIA studies on the use of PI-based ART with NRTI resistance Considerations for the use of PIs...

In this episode, Karen Ha, MD, explores recommendations and data on the role of NNRTIs in current practice. Listen as she gives her perspectives on: DHHS guideline recommendations on the use of NNRTI-based ART Weight gain data from the ADVANCE study, DRIVE-AHEAD, DRIVE-FORWARD, DRIVE-SHIFT, and a multivariate analysis of weight gain on ART Key food effects and drug–drug interaction considerations...

In this episode, Renslow Sherer, MD, discusses key data on COVID-19 oral antiviral agents—molnupiravir and nirmatrelvir (PF-07321332) plus ritonavir—for nonhospitalized adults with mild to moderate COVID-19, including: EPIC-HR study of nirmatrelvir (PF-07321332) plus ritonavir Safety data Efficacy data MOVe-OUT study of molnupiravir Safety data Efficacy data Roles in treatment of COVID-19 Timing o...

In this episode, Christian R. Pollard provides his perspectives as an individual taking daily oral HIV PrEP, including factors he considered in the decision to use PrEP, his experience with taking PrEP (daily pills and periodic laboratory testing), and his thoughts on what opportunities future PrEP options may offer. Presenter: Christian R. Pollard Content based on an online CME program supported...

In this episode from the series “Key Decisions in HIV Care,” W. David Hardy, MD, and Josep M. Llibre, MD, PhD, discuss important considerations for ART use in the context of virologic failure and resistance, including: A discussion of the definitions of the following: highly treatment experienced, complex ART, multidrug-resistant HIV, and limited treatment options The scope of the problem, includi...

Hear insights from 3 faculty experts as they present emerging data and guidelines and engage in discussion on patient-centered ART selection for people with HIV. Topics include assessing treatment options; individualizing ART for women of childbearing potential and during pregnancy, patients with OIs, and during the COVID-19 pandemic; and new data on investigational ART strategies.  Learn how to:...

In this episode from the series “Key Decisions in HIV Care,” Jonathan Appelbaum, MD, FACP, AAHIVS, and Jens D. Lundgren, MD, DMSc, discuss important considerations for ART use in older PWH, including: DHHS, EACS, IAS, and WHO recommendations for first-line ART Virologic outcomes for older PWH in clinical trials and results from the HealthHIV Second Annual National Survey Polypharmacy and its poten...

Hepatitis delta is the most severe form of viral hepatitis, and many patients remain undiagnosed. In this episode, Maria Buti, MD, and Robert G. Gish, MD, discuss the prevalence and severity of hepatitis delta. Hear their personal experiences from the clinic and their call to action for universal screening of patients with hepatitis B for coinfection with hepatitis delta. Presenters: Maria Buti, M...

In this episode, Milena Murray, PharmD, MSc, BCIDP, AAHIVP, explores recommendations and data on patient specific factors associated with LA CAB plus RPV failure. Listen as she gives her perspectives on: LA CAB plus RPV pharmacokinetic data DHHS guideline recommendations on which patients can be considered for LA CAB plus RPV Data from the ATLAS, FLAIR, and ATLAS-2M studies on patients with virolo...

In this episode, Geoffrey Dusheiko, FRCP, FRCP (Edin), FCP (SA), and Ming-Lung Yu, MD, PhD, discuss key racial inequities of care that lead to undertreatment for migrant populations and other racial minorities globally with or at risk for hepatitis B. In addition, they discuss plans to improve engagement across the care continuum and strategies to combat implicit racial biases that affect optimal...

In this episode, Dalilah Restrepo, MD, discusses barriers to shingles vaccination and strategies to increase routine vaccine uptake in the COVID-19 era. Using the latest data and expert guidance, this podcast covers topics such as: Shingles disease burden and increasing incidence over time Decline in shingles vaccination rates in the COVID-19 era National Vaccine Advisory Committee standards of ca...

In this episode, Renslow Sherer, MD, discusses key data on COVID-19 vaccine efficacy, including: Third doses Booster doses Mixing and matching booster doses Presenter: Renslow Sherer, MD Director , International HIV Training Center Professor of Medicine Section of Infectious Diseases and Global Health Department of Medicine University of Chicago Chicago, Illinois Review the downloadable slideset a...

In this episode, Martin C. Mahoney, MD, PhD, discusses new data on vaccine-preventable diseases from IDWeek 2021, including: Pneumococcal disease Respiratory syncytial virus (RSV) Herpes zoster Influenza Presenter: Martin C. Mahoney, MD, PhD   Professor of Oncology Department of Internal Medicine Roswell Park Comprehensive     Cancer Institute Buffalo, New York   Follow along with an expanded slid...

In this episode, Nancy Reau, MD, discusses new viral hepatitis data from AASLD 2021, including: HBV treatment in pregnancy Outcomes following HBV treatment withdrawal   Progress toward an HBV cure HCV implementation science and current status of the cascade of care Hepatitis delta virus: understanding the clinical impact Phase III clinical trial updates for hepatitis delta virus, including data on...

In this episode, Tristan J. Barber, MA, MD, FRCP, discusses new HIV data from EACS 2021, including: First-line therapies BIC/FTC/TAF in a test-and-treat model in IMEA 055 FAST Week 144 data of ISL + DOR in treatment-naive patients from P011 Switch Strategies Data on the use of DTG/3TC in patients with an M184V mutation from SOLAR 3D and the French Dat’AIDS Cohort Long-Acting Therapies Efficacy and...