Decera Clinical Education Infectious Disease Podcast

In this episode, hear HIV activist Marc Thompson share his perspectives on aging with HIV including:  His early experiences after receiving his diagnosis Persisting issues of the HIV epidemic including stigma and discrimination Changes in healthcare with the advent of HIV treatment Added issues of aging with HIV like polypharmacy, multimorbidity, and mental health concerns (eg, loneliness, social...

In this episode, Stefan Zeuzem, MD, discusses new viral hepatitis data from EASL 2022, including: Novel HBV therapeutics, including the REEF-2, B-Clear, and SAVE-1 studies HBV cure from the Everest Project in China HDV therapeutics from MYR301 and a study of bulevirtide in patients with cirrhosis and portal hypertension HCV retreatment in patients with prior direct-acting antiviral therapy failure...

In this episode, Nancy Reau, MD, discusses new viral hepatitis data from EASL 2022, including: Novel therapeutics for HBV Therapeutic vaccination for HBV Emerging treatment options for HDV HCV care cascade HCC monitoring after HCV cure Presenter:  Nancy Reau, MD Professor of Medicine Chief , Section of Hepatology Associate Director , Solid Organ Transplantation Richard B. Capps Chair of Hepatology...

In this episode,  Carla S. Coffin, MD, MSc, shares her thoughts on the different investigational approaches under evaluation for their potential to achieve HBV cure, including entry inhibitors, capsid inhibitors, siRNAs, immune modulators, TLR agonists, therapeutic vaccines, and checkpoint inhibitors. Presenter: Carla S. Coffin, MD, MSc Professor of Medicine Division of Gastroenterology and Hepato...

In this episode, Yvette Raphael provides her perspectives and advice as an individual living with HIV in South Africa for more than 20 years. She shares her experiences and ideas for how to improve processes related to HIV diagnosis, care linkage, and treatment. Presenter: Yvette Raphael Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc....

In this episode,  Pietro Lampertico, MD, PhD, discusses what to do when treatment for hepatitis B virus (HBV) infection is not indicated, covering topics such as: The different phases of chronic HBV infection Which patients in different phases require immediate HBV treatment and which can be monitored without therapy The critical importance of ongoing monitoring for patients who do not meet indica...

In this episode, Michelle D. Collins-Ogle, MD, FAAP, FPIDS, AAHIVS, explores the data and recommendations for HIV postexposure prophylaxis (PEP). Listen as she gives perspectives on: The CDC algorithm for evaluation and treatment of  potential HIV exposures The CDC guideline preferred and alternative PEP antiretroviral therapy regimens Data for the use of the single-tablet regimen bictegravir/emtr...

In this episode, Michelle D. Collins-Ogle, MD, FAAP, FPIDS, AAHIVS, explores key considerations for choosing antiretroviral therapy (ART) for pediatric patients. Listen as she gives perspectives on: Department of Health and Human Services (DHHS) guideline recommendations for infants at risk for perinatal HIV transmission DHHS guideline–recommended ART regimens for children The ODYSSEY A and B stud...

In this episode, Michelle D. Collins-Ogle, MD, FAAP, FPIDS, AAHIVS, explores key considerations for transgender people with HIV (PWH). Listen as she gives perspectives on: Department of Health and Human Services (DHHS) guideline recommendations for transgender PWH Providing HIV care within a gender-affirmative care model, including discussion of strategies, barriers, and facilitators Gender-affirm...

In this episode, Sharon R. Lewin, AO, FRACP, PhD, FAHMS, discusses:   Principles for antiviral agent use in nonhospitalized patients Preferred and alternative treatment options Treatment prioritization when there are logistical or supply constraints Outpatient remdesivir use PINETREE data (adult patients) CARAVAN data (pediatric patients) FDA approval and treatment candidacy Therapeutic updates Iv...

In this episode, Dexter James Wiseman, MD, discusses immunology and RSV vaccine development for older adults, including: Need for a vaccine Economic burden of RSV Reasons for poor outcomes in older adults Investigational vaccines Presenter:  Dexter James Wiseman, MD Clinical Research Fellow NHLI Imperial College Physician Respiratory Medicine Royal Brompton Hospital London, United Kingdom Review t...

In this episode, Dexter James Wiseman, MD, discusses the epidemiology and risk factors for RSV in older adults, including: Overview Disease burden based on age Seasonality Impact in care facilities Effects of the COVID-19 pandemic Presenter:  Dexter James Wiseman, MD Clinical Research Fellow NHLI Imperial College Physician Respiratory Medicine Royal Brompton Hospital London, United Kingdom Review...

In this episode, Dexter James Wiseman, MD, discusses the impact and diagnosis of RSV in older adults, including: Risk factors for poor outcomes RSV vs influenza outcomes RSV symptoms RSV diagnostics Presenter:  Dexter James Wiseman, MD Clinical Research Fellow NHLI Imperial College Physician Respiratory Medicine Royal Brompton Hospital London, United Kingdom Review the downloadable slideset and th...

In this episode, listen as Robert G. Gish, MD, discusses key information on comparing current HBV vaccine formulations, and learn the best immunization practices for routine vaccination, including in special situations. Presenter: Robert G. Gish, MD Professor of Medicine Loma Linda University Loma Linda, California Adjunct Professor of Medicine Nevada School of Medicine Las Vega, Nevada Clinical P...

In this episode, learn about the importance of identifying adults at risk for reduced hepatitis B virus (HBV) seroprotection and applying current HBV vaccine recommendations in special populations. Listen as Robert G. Gish, MD, discusses key information on the identification and evaluation of patients who have chronic health conditions and therefore may be at risk for nonresponse to available vacc...

In this episode, learn about the importance of hepatitis B virus (HBV) vaccination in adults. Listen as Robert G. Gish, MD, discusses key data on the burden and impact of HBV infection, and strategies to overcome barriers to HBV vaccination. Robert G. Gish, MD Professor of Medicine Loma Linda University Loma Linda, California Adjunct Professor of Medicine Nevada School of Medicine Las Vega, Nevada...

Hepatitis delta virus (HDV) is the most severe form of viral hepatitis, yet many patients go undiagnosed. Increasing HDV awareness is an important step to correct this and ensure that at-risk patients receive screening and then treatment and monitoring following a positive test. Hear Grace LH Wong, MD, and Ming-Lung Yu, MD, PhD, discuss a call to action to increase healthcare professional and pati...

In this episode, Norah Terrault, MD, MPH, and a patient who has been cured of hepatitis C virus (HCV) infection discuss the importance of universal HCV testing for all adults, as well as the ease of curative therapies and the benefits of living with improved liver function post cure.  This insightful discussion underscores how perceptions around HCV transmission risks and lack of symptoms serve as...

In this episode from the series “Key Decisions in HIV Care,” Cristina Mussini, MD, and William R. Short, MD, MPH, AAHIVS, discuss novel therapies for HIV prevention and treatment, including:  Prevention Cabotegravir for pre-exposure prophylaxis (PrEP) with the latest results from the HPTN 083 and HPTN 084 studies Novel PrEP therapies in development, including islatravir and lenacapavir Initial the...

In this podcast, Dr Dominique Laurent Braun discusses his micro-elimination program, the Swiss HCVree trial, designed to prevent hepatitis C virus (HCV) transmission among HIV-positive men who have sex with men. The study employed a test-and-treat approach to eliminate HCV infection in this key target population and could be a model for other countries to eliminate HCV infection in certain populat...

Antiviral agents continue to be effective against different strains of SARS-CoV-2 when used early in the disease course. In this episode, learn about the role of antiviral agents in hospitalized and high-risk nonhospitalized patients with COVID-19 and in different age groups. Listen as David A. Wohl, MD, discusses when and how to use IV and oral antiviral agents including: Nirmatrelvir + ritonavir...

The place of monoclonal antibodies in COVID-19 is changing. In this episode, learn about their role in prophylaxis of patients who are at high risk of complications from acquiring COVID-19 or treatment of high-risk patients who have a mild to moderate COVID-19 infection. Listen as Gregory Huhn, MD, MPHTM, discusses when and how to use monoclonal antibodies including: Bebtelovimab Cilgavimab/tixage...

In this episode, Oluwaseun Falade-Nwulia, MBBS, MPH, and a patient with previous injection drug use who has been cured of HCV infection discuss critical barriers that are preventing more people with current or previous injection drug use from receiving appropriate HCV care. This insightful discussion underscores the negative effects of stigma toward people who inject drugs that exist in many clini...

In this episode, Renslow Sherer, MD, discusses what is known to date regarding long COVID, also known as postacute sequelae of COVID-19 infection, including: Possible causes and risk factors Signs and symptoms Clinical management Treatment options under consideration Role of vaccination Presenter:  Renslow Sherer, MD Director , International HIV Training Center Professor of Medicine Section of Inf...

In episode 7 of a series of sharing sessions between a physician and patient, Ming-Lung Yu, MD, PhD, and his patient, who is living with chronic hepatitis B, discuss: Role of family history in risk of hepatocellular carcinoma (HCC) Surveillance for HCC Steps to take when diagnosed with HCC How to live a healthy life after HCC diagnosis and treatment Presenter :  Ming-Lung Yu, MD, PhD Chair Profess...