Decera Clinical Education Infectious Disease Podcast

An RSV vaccine, if approved, may reduce disease burden in older adults. In this recap of the most common questions from a symposium at the Family Medicine Experience 2022 conference, listen as we discuss when an RSV vaccine may be approved and how to overcome barriers to the implementation of vaccines for older adults in primary care settings. Hear answer to questions such as: When might potential...

In this episode, Deondre Moore and Samantha V. Hill, MD, MPH, discuss some of the barriers to genuinely patient-centered HIV care in the United States and offer calls to action for healthcare professionals for responding to patient preferences. They talk through some of the barriers that patients face, from struggling with unfamiliar medical terminology, to healthcare professional biases, to more...

In this episode, Samantha Strong, PharmD, BCACP, AAHIVP, CDCES, discusses closing the HIV pre-exposure prophylaxis (PrEP) gap for Black cisgender women, including: Racial inequities in PrEP access Addressing barriers to PrEP for cisgender women such as lack of education and awareness, low perceived risk of HIV, healthcare professional bias, and medical mistrust Closing the PrEP gap through educati...

When it comes to managing older adults with hepatitis B virus (HBV), what comorbidity, comedication, and adherence issues should be considered? Listen as Graham R. Foster, FRCP, PhD, discusses these considerations and more for strategizing the monitoring and treatment of older adults with HBV.  Presenter:  Graham R. Foster, FRCP, PhD Professor of Hepatology The Liver Unit Consultant Hepatologist Q...

In this episode, Latesha Elopre, MD, MSPH, discusses closing the HIV pre-exposure prophylaxis (PrEP) gap for Black men who have sex with men (MSM), including: Racial inequities in PrEP access Considering strategies to address barriers to PrEP uptake and persistence among Black MSM Considering individualized PrEP options On-demand oral emtricitabine/tenofovir disoproxil fumarate (2:1:1) Injectable...

In this episode, Timothy J. Wilkin, MD, MPH, provides a case-based overview of switching antiretroviral therapy in a patient with viral suppression on their current regimen who has a history of virologic failure with drug-resistance mutations. Key findings from 2 relevant studies—the SWITCHMRK trial and Study 380-4030—are reviewed. The case discussion also highlights several other challenges that...

In this episode, Tristan J. Barber, MA, MD, FRCP, and Darcy Wooten, MD, discuss switching ART with virologic suppression, including: Switching with prior or unknown resistance Data on switching to BIC/FTC/TAF with a preexisting M184V/I mutation from a pooled analysis of 6 phase III studies The impact of baseline resistance on outcomes following a switch to BIC/FTC/TAF in Black PWH from the BRAAVE...

In this episode, Lilian Abbo, MD, FIDSA; Julie Ann Justo, PharmD, MS; and David van Duin, MD, PhD, FIDSA, FAST, discuss key concepts about extraintestinal pathogenic Escherichia coli , including: Diverse strains and virulence factors associated with invasive disease Antimicrobial resistance profiles seen in clinical practice Various disease manifestations Prevalence and burden of invasive infectio...

In this podcast, Gary S. Marshall, MD, summarizes the burden of meningococcal disease and the importance of immunization, including:  The unpredictability and severity of meningococcal disease Differences between meningococcal serogroups and available vaccines  Current meningococcal vaccine recommendations, distinguishing between routine vs shared clinical decision-making recommendations  Vaccine...

In this episode, Cristina Mussini, MD, shares her approach to caring for aging patients with HIV. This includes not just focusing on their HIV, but their over well-being, such as: Maintaining a healthy weight, eating healthy and staying mobile  Overcoming the obstacle of stigma from society and self-stigma Empowering patients to care for themselves In women who are often caregivers most of their l...

How do we define “older” in our older patients living with hepatitis B virus (HBV)? What monitoring and treatment options should be considered for these older patients with chronic HBV infection? Listen as Nancy Reau, MD, discusses strategies and considerations for monitoring and treating older adults with HBV, illustrated with a patient case. Presenter: Nancy Reau, MD Professor of Medicine Chief...

In this episode, listen to Priscilla Y. Hsue, MD, and Jens D. Lundgren MD, DMSc, discuss the latest data about ARV-related weight gain and cardiometabolic toxicities in PWH. Hear faculty: Review risk factors associated with significant weight gain Consider possible implications of weight gain and cardiometabolic toxicities Share their approaches to ARV-related weight gain and/or cardiometabolic to...

In this episode, Chloe Orkin, MBChB, FRCP, MD, discusses new HIV data from AIDS 2022, including: Prevention strategies Oral therapies LA therapies Cure COVID-19 in PWH Faculty Chloe Orkin, MBChB, FRCP, MD Professor of HIV Queen Mary, University of London Consultant Physician Lead for HIV Research Barts Health NHS Trust The Royal London Hospital London, United Kingdom Follow along with the slides a...

In this episode, Roger Bedimo, MD, MS, FACP, discusses key considerations for switching ART in virologically suppressed patients who are pregnant or trying to conceive. His discussion includes: DHHS Perinatal Guideline recommendations French Perinatal Cohort study on the implications of viral suppression when changing ART in the first trimester of pregnancy IMPAACT 2010 Update on the safety and ef...

In this podcast, Melanie Reese, a woman aging with HIV, shares her perspectives on the added challenges faced by older women with HIV—an underserved, underresourced, and underresearched group—and talks about potential solutions that should be considered, such as: Listen and prioritize concerns brought to you by older women with HIV to improve trust in you and the medical profession Promote self-ad...

In this episode, listen to Dorothy Onyango, patient and patient activist, share her views on the many barriers encountered by aging patients with HIV living in resource-limited settings and the need to work on solutions to overcome such barriers, including: The major burden of poverty affecting access to care/medications, healthcare services (eg, treatment for noncommunicable diseases, home-based...

In this episode,  an international expert panel shares their thoughts on key considerations for incorporating long-acting cabotegravir as an additional HIV pre-exposure prophylaxis option for appropriate individuals at high risk of acquiring HIV infection. Topics include anticipated patient interest in this new paradigm, the role of the oral lead-in phase, new guideline recommendations for monitor...

In this podcast, Jonathan Appelbaum, MD, FACP, AAHIVS, summarizes the many medical challenges faced by aging people with HIV, including: Underrepresentation of older patients in medical research Consequences of early experiences in the epidemic such as late HIV diagnosis and low CD4+ cell count nadir, incomplete or short-lived virologic suppression with early regimens, and toxicity associated with...

In this episode, Babafemi Taiwo, MBBS, discusses strategies for reaching people with HIV who are not yet diagnosed. His overview includes: HIV diagnosis by global region Disparities in serostatus awareness Patient perspective on importance of HIV testing Barriers to HIV diagnosis Complications from late HIV diagnosis Strategies to improve rates of HIV testing Presenter: Babafemi Taiwo, MBBS​ Gene...

In this episode, Chloe Orkin, MBChB, FRCP, MD​, discusses strategies for successful antiretroviral therapy (ART) initiation. Her overview includes: Recommendations for rapid ART First-line ART regimens for treatment-naive people with HIV IMEA 055 FAST study STAT study DIAMOND study Antiretroviral resistance mutations Patient perspectives on the importance of rapid ART initiation Presenter: Chloe O...

In this episode, Nagalingeswaran Kumarasamy, MBBS, FRCP, PhD, discusses the importance of linking people to care after a positive HIV diagnosis. His overview includes: HIV care continuum Factors that delay linkage to care Organized strategies to improve linkage to care for people with HIV Interventions that may improve linkage to care for people with HIV Patient perspective on how to engage patien...

In this episode, hear Dr. Jean Rene Anderson and Dr. William Short discuss special factors to consider when selecting HIV treatments during pregnancy, including: Key elements involved in evaluating ARV medications during pregnancy (eg, efficacy, pharmacokinetic, and safety data) Approach to optimizing ART regimens prior to and during pregnancy Faculty: Jean Rene Anderson, MD Professor Department o...

You can think of the “D” in HDV as standing for difficult, disadvantaged, and dangerous. Hepatitis delta virus (HDV) is difficult to diagnose, is often diagnosed in disadvantaged patient populations, and leads to dangerous sequelae. Listen as Dr. Kosh Agarwal and Dr. Graham R. Foster and discuss challenges and opportunities for linking patients to care after a positive test for HDV. Presenters: Ko...

In this episode, an international expert panel shares their thoughts on key considerations at the operational level for incorporating long-acting injectable antiretroviral therapy into the HIV treatment armamentarium. Topics include the duration of injection appointments in real-world settings, managing additional patient volume/workload (particularly the key role of nurses), and preventing and ad...

In this episode,  an international expert panel shares their thoughts on key steps for switching patients to long-acting injectable cabotegravir plus rilpivirine for HIV treatment, including selecting the most appropriate patients, introducing patients to the long-acting option, and preparing patients for what to expect from long-acting treatment in terms of efficacy, visit timing, and the injecti...