Decera Clinical Education Infectious Disease Podcast

 In this episode, 2 Australian HIV experts share their thoughts on some of the most important HIV insights gained during the past year in the context of HIV care in Australia. Specifically, the faculty discuss the continued dominance of second-generation INSTI-based regimens as mainstay HIV therapy in Australia, including in both 2-drug and 3-drug oral regimens; the emergence of 2-drug long-acting...

In this episode, 2 European HIV experts share their thoughts on some of the most important new antiretroviral therapy insights from HIV research over the past year. Specifically, the faculty discuss findings from real-world and long-term studies of 2-drug oral regimens, the latest on 2-drug long-acting injectable therapy, how 2-drug options fit into rapid start strategies, and other new and emergi...

In this episode, Alba Azola, MD, and Monica Verduzco-Gutierrez, MD, discuss diagnosis and management of long COVID, including:  Definitions of post COVID conditions Diagnosis, including symptoms and clinical presentation Epidemiology Risk factors Possible treatment options Clinical guidance statements Presenters: Alba Azola, MD Assistant Professor Department of Physical Medicine and Rehabilitation...

In this episode, Kenric Ware, PharmD, AAHIVP, discusses the role of college campuses in HIV pre-exposure prophylaxis (PrEP) uptake for adolescents, including the following. PrEP awareness and education Venues for ongoing PrEP conversations, including in-person dormitory discussions, virtual webinars, and social media conversations Campus health clinics that are safe and trusting and minimize stigm...

In this episode, Eric Florence, MD, PhD, discusses how clinics can prepare for the implementation of long-acting injectable antiretroviral therapy, including: Clinical infrastructure Ensuring adequate space and injection equipment Maintaining drug supply and temperature requirements Staffing Ensuring there are staff able to focus on the implementation of LA ART, including well-trained nurses to ad...

In this episode, Marta Boffito, MD, PhD, FRCP, and Jens D. Lundgren, MD, DMSc, address key considerations when evaluating antiretroviral therapy safety and tolerability in aging patients and those with possible cardiometabolic toxicities, including: Monitoring for cardiometabolic syndromes (eg, lipid panels, coronary artery calcification scores) Approaching antiretroviral-related weight gain in cl...

In this episode, Jens D. Lundgren, MD, DMSc, and Barbara Rath, MD, PhD, HDR, discuss emerging insights on outpatient management of acute COVID-19 and long COVID in Europe, including: Current COVID-19 variant and subvariant landscape COVID-19 treatments, including antivirals and monoclonal antibodies ESCMID COVID-19 treatment guidelines Long COVID causes and pathophysiology Prevention and managemen...

In this episode, Laurence Slama, MD, PhD, describes some of the ways that her clinic is attempting to make IM injections of long-acting antiretroviral therapy more sustainable long term. She explains the logistics of how she has allowed for patients to receive their long-acting cabotegravir and rilpivirine doses through community nurses after receiving the first 3 doses in a clinical setting. She...

In this episode, Jason E. Farley, PhD, MPH, ANP-BC, FAAN, FAANP, AACRN, discusses optimizing HIV pre-exposure prophylaxis (PrEP) selection and persistence for men who have sex with men (MSM), including: Disparities in PrEP uptake for MSM What healthcare professionals can do to address disparities in PrEP uptake Providing PrEP within a program that includes sexual health and primary care services,...

In this episode, Jill Blumenthal, MD, MAS, discusses HIV pre-exposure prophylaxis (PrEP) considerations for transgender and nonbinary individuals, including: Providing gender-affirming care Integrating PrEP and gender care Taking a sexual history and addressing sexual health PrEP efficacy and options for transgender individuals, including FTC/TDF, FTC/TAF, and long-acting CAB The importance of rea...

Fernando Carnavali, MD; Rasika Karnik, MS, MD; Renslow Sherer, MD; and Joseph Torrisi, PharmD, BCIDP, discuss COVID-19 treatments and the possibility for antiviral resistance, including: Treatment resistance mechanisms COVID-19 testing COVID-19 treatments, including antivirals and monoclonal antibodies Presenters: Fernando Carnavali, MD Associate Professor of Medicine Division Chief General Intern...

Fernando Carnavali, MD; Rasika Karnik, MS, MD; and Renslow Sherer, MD, discuss long COVID, including: Long COVID prevention strategies, including COVID-19 vaccination Long COVID treatment approaches Strategies for management of patients with long COVID Presenters: Fernando Carnavali, MD Associate Professor of Medicine Division Chief General Internal Medicine Department of Medicine Site Director CO...

In this episode, Princy N. Kumar, MD, FIDSA, MACP, discusses key considerations for selecting ART in treatment-naive persons with HIV. Her discussion includes a review of the following studies on ART and weight gain: ADVANCE: men vs women receiving DTG + FTC/TAF, DTG + FTC/TDF, and EFV + FTC/TDF Comparison of ART regimens (eg, INSTI-, NNRTI- and PI-based regimens) in a pooled analysis of 8 phase I...

Fernando Carnavali, MD; Rasika Karnik, MS, MD; Renslow Sherer, MD; and Joseph Torrisi, PharmD, BCIDP, discuss COVID-19 rebound, including: Prevalence of COVID-19 rebound COVID-19 rebound and antiviral use Management of COVID-19 rebound  Presenters: Fernando Carnavali, MD Associate Professor of Medicine Division Chief General Internal Medicine Department of Medicine Site Director  COVID Center of E...

In this episode, Princy N. Kumar, MD, FIDSA, MACP, discusses key considerations for selecting ART in treatment-naive persons with HIV. Her discussion includes: DHHS Treatment Guideline recommendations Choosing among first-line recommended integrase inhibitors Recommended regimens for rapid ART start Select key studies in treatment-naïve adults: AMBER study of virologic response with DRV/COBI/FTC/T...

Fernando Carnavali, MD; Rasika Karnik, MS, MD; Renslow Sherer, MD; and Joseph Torrisi, PharmD, BCIDP, discuss how to ethically prioritize patients for COVID-19 treatment when treatment supplies may be limited, including insights on: Risk stratification Medication acquisition Drug interactions Presenters: Fernando Carnavali, MD Associate Professor of Medicine Division Chief General Internal Medicin...

In this episode, Tamera Coyne-Beasley, MD, MPH, discusses strategies to address barriers to improve meningococcal vaccination rates by addressing social determinants of health and minimizing vaccine inequities, such as: Working closely with members of the community, including community-based organizations and adolescent and young adult influencers Involving all youth when designing vaccination out...

Fernando Carnavali, MD; Renslow Sherer, MD; and Joseph Torrisi, PharmD, BCIDP, discuss how new COVID-19 vaccines may affect risk stratification, including: Omicron-specific vaccine Role of vaccination in risk stratification Presenters: Fernando Carnavali, MD Associate Professor of Medicine Division Chief General Internal Medicine Department of Medicine Site Director  COVID Center of Excellence Sat...

In this episode,  an international expert panel shares their thoughts on what will be needed from future long-acting HIV treatment and prevention strategies to address populations who are not eligible for currently available long-acting options. The faculty members also discuss important considerations for leveraging long-acting HIV approaches to address care inequities across different population...

In this episode, Carolyn Chu, MD, MSc, FAAFP, AAHIVS, discusses improving HIV pre-exposure prophylaxis accessibility and availability for PWID, including by: Integrating PrEP with services that PWID are already aware of and/or connected to (eg, harm reduction/syringe services and substance use disorder treatment programs, peer-based training/education initiatives, healthcare for the homeless progr...

In this episode, Monica Gandhi, MD, MPH, and Chloe Orkin, MBChB, FRCP, MD, discuss considerations for monkeypox, now called mpox, in people with HIV, including: The history of monkeypox (mpox) The current monkeypox (mpox) outbreak What we knew about monkeypox (mpox) in PWH prior to the current outbreak Data in PWH from an international case series of monkeypox (mpox) CDC data regarding monkeypox (...

In this episode, Annette Haberl, MD, and William R. Short, MD, MPH, AAHIVS, discuss when to consider an ART switch during pregnancy, including: Current DHHS, EACS, WHO, BHIVA, and German/Austrian guidelines for the use of ARVs in pregnancy What data and recommendations for the use of ARVs during pregnancy are currently missing from the guidelines Available data on newer ARVs in the ARV pregnancy r...

In this episode, Stephane De Wit, MD, PhD, discusses the benefits of long-acting antiretroviral therapy (ART) for migrant populations in Europe—and specifically in Belgium. He also addresses some of the challenges of accessing and following up with those populations. Dr De Wit describes some of the ways that the Belgian healthcare system is set up to improve access to ART. He then explains some of...

In this episode, Nancy Reau, MD, and Coleman I. Smith, MD, discuss the burden of undiagnosed hepatitis delta virus (HDV) infection and who should be tested, including: Epidemiology of HDV infection Clinical course of HDV infection Populations at high risk of HDV infection Guidelines for HDV testing Faculty:  Nancy Reau, MD Professor of Medicine Chief,  Section of Hepatology  Associate Director,  S...

When it comes to managing adults with HBV, should age factor into your treatment decision—or is it important to treat everyone, regardless of age? Listen as Dr George Lau discusses these questions and more for strategizing the monitoring and treatment of older adults with HBV.  Presenter:  George Lau, MBBS (HKU), MD (HKU), FRCP (Edin, Lond), FAASLD (USA) Chairman Humanity and Health Medical Group...