DASON Digest

In this exciting episode, Drs. Libby Dodds Ashley and Jeannette Bouchard are joined by Dr. Jason Roberts to discuss his two newly published articles in JAMA that help to answer the question: is there a difference between continuous and intermittent infusions of beta-lactam antibiotics, especially in the critically ill populations? The reviewed materials can be found here: https://dason.medicine.du...

In this episode of the DASON Digest podcast, DASON Clinical Pharmacist Liaison Dr. Angelina Davis talks to us about the use of AI in the management of bloodstream infections. The article reviewed can be found here: https://academic.oup.com/cid/article-abstract/78/4/825/7308526

Episode Notes In this episode, Dr. Jeannette Bouchard discusses a newly published article in JAMA about the use of piperacillin-tazobactam and cefepime in sepsis. This episode also ties into a previous episode (#74) and we would recommend listening to both episodes! The article reviewed in this episode can be found here: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2818278 For...

Episode Notes In this episode, University of Kentucky Infectious Diseases Pharmacy Residents, Will Harris and Tyler Pitcock, review a recently published article evaluating the impact of the implementation of rapid blood culture identification technology and stewardship intervention on treatment of blood cultures contaminated with coagulase-negative staphylococci. The article reviewed in this episo...

Episode Notes In this episode, University of Kentucky PGY2 Infectious Diseases Pharmacy Residents, Will Harris and Tyler Pitcock, discuss the recently published article evaluating the efficacy of the clinical decision tool, PEN-FAST, in de-labeling patients with reported penicillin allergies with one of the authors and Duke University Hospital Infectious Diseases Physicians, Dr. Nick Turner. The a...

Episode Notes In this episode, Duke University Hospital Infectious Diseases Pharmacist Dr. Rebekah Wrenn and her resident, Amy Mackowiak, review Dr. Wrenn's recently published article evaluating the impact of default duration elimination on exposure to fluoroquinolone therapy.  The article reviewed in today's episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38347810/ For more information...

Episode Notes In this episode of the DASON Digest Podcast, one of our DASON Clinical Pharmacist Liaisons, Dr. Melissa Johnson, talks with Dr. Jim Lewis, ID Clinical Pharmacy Coordinator and Adjunct Associate Professor at Oregon Health & Science University Departments of Pharmacy and ID in Portland, Oregon. The material reviewed in today's podcast can be found here: https://clsi.org/standards/p...

Episode Notes In this episode of the DASON Digest podcast, DASON Clinical Pharmacist Liaison Dr. April Dyer talks to us about how to incorporate adverse event feedback into antibiotic stewardship. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38415083/ For more information about DASON, please visit: https://dason.medicine.duke.edu

Episode Notes In this episode, DASON Clinical Pharmacist Liaisons Drs. Jeannette Bouchard and Libby Dodds-Ashley walk us through the details of a recent article published in ASHE to assess the impact of a clinical decision support survey to improve GI Panel ordering appropriateness at a VA. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38415090/ For more i...

Episode Notes In this episode of the DASON Digest podcast, DASON Clinical Pharmacist Liaison Dr. Angelina Davis talks to us about the use of active versus passive methods of responding to rapid diagnostic blood culture results. The article reviewed can be found here: https://pubmed.ncbi.nlm.nih.gov/36483427/ For more information about DASON, please visit: https://dason.medicine.duke.edu/

Episode Notes In this episode, DASON Clinical Pharmacist Liaison Dr. Jeannette Bouchard is joined by Dr. Kevin Garey, an adjunct professor at the University of Texas School of Public Health and senior author of the reviewed article. They walk us through the details of the microbiome effects oral omadacycline has versus oral vancomycin and what this might mean for the future of the treatment for C....

Episode Notes In this episode, DASON Clinical Pharmacist Liaisons Drs. Melissa Johnson and Jeannette Bouchard discuss an article from ASHE on high-dose oral beta-lactam definitive therapy compared to fluoroquinolone or trimethoprim-sulfamethoxazole oral therapy for bacteremia secondary to a urinary tract infection. The article reviewed can be found here: https://pubmed.ncbi.nlm.nih.gov/37771747/ F...

Episode Notes In this episode, Dr. April Dyer, one of our DASON Clinical Pharmacist Liaisons, talks to us about source specific order sets leading to improved empiric therapy in the ED in a 200 bed hospital. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofad677/7491622# To learn more about DASON, please visit: https://dason.m...

Episode Notes In this episode, Drs. Bouchard, Dodds Ashley, and Perez review a large study tackling inappropriate antimicrobial use in the outpatient setting. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofad585/7439469 For more information about DASON, please visit: https://dason.medicine.duke.edu

Episode Notes In this episode, Drs. Libby Dodds Ashley and Jeannette Bouchard, two of our DASON Clinical Pharmacists, talk to us about bringing and end to VAP. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37888914/ For more information about DASON, please visit: https://dason.medicine.duke.edu

Episode Notes This week we would like to use the feed to share a great episode of Sara Dong's podcast "Febrile."  Members of our DASON team and the Society for Healthcare Epidemiology of America's antimicrobial stewardship committee celebrate antibiotic awareness week by discussing stewardship teams and an example case.

Episode Notes In this episode, Dr. April Dyer, one of the DASON Clinical Pharmacists, talks about cefepime vs piperacillin-tazobactam in adults hospitalized with acute infection. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37837651/ For more information about DASON, please visit: https://dason.medicine.duke.edu

Episode Notes Drs. Perez, Hillenbrand and Mourad do a deep dive on how to best apply one of our most common stewardship tools. The article reviewed in this episode can be found here: https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciad467/7240295 For more information about DASON, please visit: https://dason.medicine.duke.edu

Episode Notes In this episode of the DASON Digest Podcast, DASON Clinical Pharmacist Liaison Dr. Jeannette Bouchard talks to us about clinical risk scores to improve empiric antimicrobial selection for outpatient complicated urinary tract infections. The article reviewed in this episode can be found here:  https://academic.oup.com/ofid/article/10/8/ofad319/7198038#413122181 For more information ab...

Episode Notes In this episode, Dr. Rey Perez chats with Drs. Rebekah Moehring and Libby Dodds Ashley about work done by the University of Pittsburgh using a weighted lottery to equitably allocate scarce supply of COVID-19 monoclonal antibody to patients. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37656472/ For more information about DASON, please visit:...

Episode Notes In this episode of the DASON Digest Podcast, DASON Clinical Pharmacist Liaison Dr. Angelina Davis talks to us about the early discontinuation of antibiotics in patients admitted with clinically suspected serious infection but negative cultures. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37449298/ For more information about DASON, please vi...

Episode Notes In this episode of the DASON Digest Podcast, DASON Clinical Pharmacist Liaison Dr. April Dyer talks to us about improving the efficiency of antimicrobial stewardship action in acute care facilities. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofad412/7234482 For more information about DASON, please visit: http...

Episode Notes Dr. Rey Perez chats with our newest DASON Clinical Pharmacist Liaison, Dr. Jeannette Bouchard, about the epidemiology of gram negative blood stream infections. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/article/10/7/ofad265/7175984 For more information about DASON, please visit: https://dason.medicine.duke.edu

Episode Notes Dr. Melissa Johnson from DASON talks to us about removing incorrect penicillin allergy labels. There are lots of supplemental materials for this episode, and they can all be viewed on the episode's page on our website: https://dason.medicine.duke.edu/blog/rx-success-tackling-penicillin-allergy-de-labelling-our-hospitals The main article discussed today is: https://pubmed.ncbi.nlm.nih...

Episode Notes In this episode, Dr. Angelina Davis talks to us about the use of clindamycin + vancomycin vs. linezolid for the treatment of necrotizing soft tissue infections. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37351452/ For more information about DASON, please visit: https://dason.medicine.duke.edu