Chromatography Life

In this episode of Chromatography Life podcast, join us for a deep dive into the world of gel permeation chromatography (GPC). Host Neil Lander sits down with GPC expert Larry Meeker, who brings more than 27 years of hands‑on experience at Waters Corporation. From helping customers master method development to supporting everyday GPC workflows, Larry has seen it all. In this episode, the two explo...

In this episode of Chromatography Life, Neil Lander and Colette Quinn, Sr. Director of Light Scattering in QC at Waters Corporation break down how the October 2025 FDA draft guidance is reshaping expectations for biosimilar development. They explore why LC and orthogonal techniques like MALS are becoming essential for demonstrating analytical similarity and reducing reliance on clinical studies. C...

In this special Year in Review episode of Chromatography Life , host Neil Lander reflects on a year of engaging conversations with both Waters colleagues and customers from across the analytical science community. Neil shares what made each episode memorable, from deep technical insights to the personal stories behind the science.

In this episode, Neil Lander sits down with renowned analytical chemist Bob McDowall to explore the complexities of chromatographic peak integration. With over 50 years of experience, Bob shares insights into data integrity, regulatory compliance, and the evolving role of manual vs. automated integration. The conversation dives into real-world examples, AI's potential role in chromatography, and b...

In our latest episode of Chromatography Life podcast, we explore a fascinating and nearly forgotten separation technique—slalom chromatography—with Dr. Fabrice Gritti, Consulting Scientist at Waters Corporation. Dr. Gritti brings decades of expertise in separation science and shares how this 1980s-era method is being revived to meet today's challenges in DNA and RNA analysis. Dr. Gritti also share...

In Episode 9 of Chromatography Life, we sit down with Richard Verseput, a pioneer in QbD-driven analytical development, to explore how automation, risk assessment, and smart experimental design are revolutionizing chromatography. From cutting-edge tools like Fusion QbD to real-world strategies for building robust, adaptable methods, this episode is packed with insights that can transform your lab'...

Join host Neil Lander as he sits down with Peter Baker, President of Live Oak Quality Assurance and former FDA Investigator of the Year, to explore the complexities of equilibration injections in regulated laboratories. Peter shares his global regulatory experience, offering insights into data integrity, risk management, and how to avoid common compliance pitfalls. This episode is a must-listen fo...

Join host Neil Lander as he sits down with Margaret Maziarz, Principal Scientist at Waters Corporation, to discuss the latest tools and strategic approaches to optimizing method development. Margaret guides us through the advantages to various types of instrumentation, the importance of selecting the right column chemistry, and the powerful capabilities of Empower software. She highlights the crit...

This episode of Chromatography Life takes a closer look at the evolving landscape of synthetic peptide drugs - one of the most compelling frontiers in biopharmaceutical analysis. Joining us is Matt Lauber, Senior Director at Waters and a recognized authority in bioanalysis and drug product characterization, who shares both his personal and professional journey, along with his insights into the sci...

Join host Neil Lander on Chromatography Life as he interviews, Arnaud Delobel, R&D and Innovation Director at Quality Assistance. In this episode, Arnaud discusses chromatographic analysis for new modalities, with adeno-associated viruses (AAVs) in the spotlight. He discusses the complexities of analyzing these large biomolecules and the innovative techniques being developed to improve their chara...

Join host Neil Lander on Chromatography Life as he interviews Ben Calvopina, Application Scientist and expert in dissolution testing at SOTAX. Ben shares his journey from service engineering to leading automation projects, highlighting the impact of automation on efficiency and accuracy in pharmaceutical quality control. The episode explores the practical aspects of automating dissolution methods...

In this episode of the Chromatography Life podcast, our host Neil Lander sits down with Tom Walter, a corporate fellow at Waters, to explore the fascinating journey of UPLC column evolution. Tom, a seasoned expert with numerous patents and innovations under his belt, shares his experiences and insights from his extensive career in chromatography. From the early days of large particle columns to th...

Join host Neil Lander as he welcomes Katy Rhynard, Associate Director of Laboratory Informatics at Gilead Sciences. In this episode, Katy discusses the intricacies of validating chromatographic methods, including guidelines and regulatory requirements, key success metrics, documentation, techniques, and tools. Katy details the pervasive challenges in method validation, and how to effectively lever...

In this episode of Chromatography Life, we're joined by Andy Meyer from Wyatt Technology to explore the tech, applications and challenges of leveraging Multi-Angle Light Scattering with Size Exclusion Chromatography (SEC). Andy delves into the intricacies of SEC, discussing columns, standards, and the innovative techniques that are enhancing detection and deliverables. Get an insider's perspective...

Welcome to Chromatography Life, a podcast presented by Waters Corporation. Join us as we dive into the world of chromatography with leading scientists to examine today's critical challenges. As a hub for the chromatography community, we share the lived experiences, passions, and visions of these scientific innovators as they shape the future of analytical chemistry.   Hear from experts across a wi...