Chemist Confessions

In 2025, the chemists want to tackle both the science and practical application of skincare. Following the pore care deep dive, the chemists review five toner pad products so you don’t have to. We discuss our thoughts on the texture and use experience from both the oily skin and dry skin perspective.

When strategizing how to tackle pores, the science is about as random as the skincare landscape. The chemists tackle the biology, the ingredients, and the skincare to try to make sense of what steps can actually make a meaningful difference to help reduce pore size. Can “glass”, “egg”, poreless skin actually achievable?

In 2025, the chemists want to tackle both the science and practical application of skincare. Following the spicules deep dive, the chemists review the top two spicule (reedle) skincare products so you don’t have to. We discuss our thoughts on the texture and use experience from both the oily skin and dry skin perspectives.

Continuing our journey of diving into exciting, trendy new ingredients, this week, the chemists take a closer look at all the science behind spicule skincare. Though these prickly bits derived from marine sponges definitely have some interesting data, we still have more questions on how to best use spicules… Let’s jump in the rabbit hole!

In 2025, the chemists want to tackle both the science and practical application of skincare. Following the PDRN deep dive, the chemists review the top two PDRN skincare products so you don’t have to. We discuss our thoughts on the texture and use experience from both the oily skin and dry skin perspective.

One of the most popular requests for us to decode is PDRN. Kbeauty continues to be at the center of trendy and exotic “new” skincare. This week, the chemists’ dive into PDRN, fragmented DNA derived from salmon sperm? They discuss what it is, how it ended up in our skincare, and if there’s any substantial evidence of PDRN’s benefits for skin. Let’s go down the rabbit hole!

We’re kicking off the 2025 podcast season with a twist. With all of our new listeners and viewers, it’s time to brush up on the fundamentals of who exactly the chemists are, how we analyze the science, and just what sort of decoding you can do to assess your skincare like an expert! Think of this as a primer into all the deep dives we’ll be getting into and an episode dedicated to getting to know...

It’s the last episode of 2024! Reflecting back on the year, we’re discussing top skincare science and animal fun facts. We also share our plans for the new year. The podcast has truly built an incredible community and we are so grateful to you all. Happy Holidays and we'll see you in 2025.

As a follow-up on last week’s episode on skincare for certain age groups, this week, let’s dive into estrogen-based skincare, in particular creams with estradiol or estriol. This prescription skincare realm aimed to treat peri and post-menopausal skin issues like irritation, redness, and dryness. So! Do they work? Are there other benefits beyond skin barrier care?

We all know that skin changes with father time, but how should you best skincare for your specific age? We discuss the science, what major timepoints to consider and what skincare you should be using in your teens, 20s, 30-40s, and 50s+.

Neck aging can be so difficult to address because of its complex biology. But can topicals do anything to help? Let’s take a closer look at 3 neck cream clincals done by Replenix, Skinceuticals, and Revision skincare to see if you really need a dedicated product just for your neck area.

The holiday season is just looming around the corner. So whether you’re taking advantage of the discounts for yourself, or on the market for loved ones, here are some of thoughts on on the beauty holiday deals. Join us for some shopping inspirations or just some laughs!

After a nice break from sunscreens, we had some time to dabble in lip SPF products. It turns out our lip skin actually has a lot less natural protection from both sun and dryness than the rest of our body. Thus, it only makes sense that having a good lip SPF (or two) is important to have handy. We tried 12 lip SPFS of various types and various price points and share all of our findings! The taste...

Today we’re going to attempt to tackle the vast landscape of peptides! It’s a big topic but sadly without a lot of clarity. So let’s nerd out with us on just what peptides are, how they work on skin, what skin concerns they’re good for, and decode a few top peptide products. 

After listening to this podcast long enough, you’ll probably get a sense that good testing data is sparse so we inevitably have to work with what we have! With the recent US ban of OTC hydroquinone products, it's worth noting that a notable few actives have done testing in direct comparison to hydroquinone. Though more testing is always needed, direct comparison studies are considered rare and top...

This is a bit overdue! Arbutin is a hyperpigmentation active with a reputation as a hydroquinone alternative. So today we’re tackling all the major questions around arbutin: Does it convert to hydroquinone on skin? Is it even a good hyperpigmentation active?

It’s time for another wet blanket type episode - dark circles Just why are dark circles so hard to deal with? Do eye creams even work? We go through the data and discuss what you can actually do to treat this stubborn and complex skin concern.

We’ve put it off for long enough, today we’re jumping into the very new, very hot realm of exosomes. These vesicle structures are getting a lot of attention because they’ve been tied to: stem cells, growth factors, fibroblasts…essentially all the juicy anti-aging good stuff. In this episode, the chemists attempt to make sense of exosomes’ true purpose in skincare, share what benefits they can brin...

We're wrapping up our acne series with a deep dive on acne patches. These face stickers often get tied to some pretty enticing claims like absorbing excess sebum and rapidly healing pimples. We discuss the science behind these mystical patches, what they actually do to acne lesions, and what are their real benefits. Finally, we end on our experiences trying 5 different acne patches on the market....

Continuing our acne series, we’ve been able to delve into some solid actives with pretty juicy data behind it, but there are quite a few less validated ingredients that are pretty popular and worth a look. In this episode, we look at succinic acid, mugwort, witch hazel, and tea tree oil. Four popular plant-ish actives that have gained some traction as magical home remedies for acne breakouts. Let’...

When it comes to fighting acne, benzoyl peroxide has been around for so long it almost seems like it’s old-fashioned. However, because of its long history, BPO has a lot of great data and of the ingredients out there we actually have a very good understanding how it works to reduce breakouts. But are we actually using the right concentration? We dive into the research and discuss what concentratio...

Salicylic acid is probably the most common active ingredient you’ll run into when putting together your acne routine. But is it actually a must have? What kind of acne can it actually treat? In this episode, we dive into a few key clinical studies that look at just what 2% salicylic acid really bring to your routine.

One of the more popular questions we get is about collagen supplements and whether or not it’s a scam. We’d be lying if we said we haven’t been avoiding this one, but no longer! In this episode, we go through the clinical data. We discuss why it’s so hard to shop for good collagen supplements. Finally, we list our shopping tips and things to consider if you’re thinking of adding this to your beaut...

After testing 30 sunscreens in 30 days, we’re finally going through our favorites! There was so much to discuss that this ended up turning into a 2 part segment. In part 2, we talked about our thoughts on baby sunscreens, international sunscreens, things we’d do differently in the future, and… pangolins? Let’s wrap the sunscreen series!

After testing 30 sunscreens in 30 days, we’re finally going through our favorites! There was so much to discuss that this ended up turning into a 2 part segment. In part 1, we discuss what factored into our ratings and why. We then go through our “0 star” ratings and why they were so painful. Finally, we discuss our favorites for the mineral and tinted category! Hope you enjoy as we tell all in ou...