Dr Daniel J. Guerra

Authentic Biochemistry

Science EN ↓ 1333 episodes

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Author

Dr Daniel J. Guerra

Episodes

Membrane Biochemistry 79. Sphingolipids and cyclic phosphatidic acid control PPAR isoform-mediated gene transcription over lipid metabolism and inflammation. DJGPhD.16.11.22. Authentic Biochemistry 16.11.2022 29:49

References Circulation Research. 2008;102:283–294 Neurochemical Research volume 45, pages 972–988 (2020) Biochim Biophys Acta. 2008 Sep; 1781(9): 519–524.

Membrane Biochemistry 78. Nuclear sphingolipid metabolism controlling cAMP response element-mediated transcription promoting proinflammation and anti-inflammation temporally and spatially.DJGPhD. 15.11.2022 29:46

References Nature Scientific Reports 2017.volume 7, Article number: 18004  Cells 2022, 11(13). https://doi.org/10.3390/cells11132020 European Journal of Endocrinology 2015. (July). 173(4). Front Pharmacol. 2020; 11: 569802.

Membrane Biochemistry 77. Membrane lipid mediated IGF-I in contextual expression within discrete organ systems controls an inflammatory valence DJGPhD. 9 November 2022 Authentic Biochemistry 10.11.2022 29:40

References Front Aging Neurosci. 2017; 9: 365 J Physiol Biochem. 2017; 73(2): 245–258 Annu Rev Physiol. 2012; 74: 131–151.

Membrane Biochemistry 76. Introduction to SubCellular-Distribution Mechanisms and Function of Nuclear-Localized Lipids. DJGPhD.06Nov22b.Authentic Biochemistry Podcast 06.11.2022 29:57

References Dr Guerra lecture notes Annu Rev Physiol. 2012; 74: 131–151.

Membrane Biochemistry75. Rational judgment as the epistimological prolegomena to research science:isoprenoid lipid biosynthesis guided event ontologies.DJGPhD.6NOV22.Authentic Biochemistry. 06.11.2022 30:00

Dr Guerra's Lecture notes 

Membrane Biochemistry 74. ER-Phosphatidylcholine biosynthesis regulates neuritigenesis and the use of logical judgment in research science. DJGPhD. 03Nov22. Authentic Biochemistry 03.11.2022 29:56

References PLoS One. 2019 Jan 10;14(1):e0210207 Nature Communications volume 9, Article number: 1784 (2018)) Cell Death & Disease volume 8, page e2897; 2017 Nat Cell Biol. 2013 Apr;15(4):373-84 Dev Neurobiol. 2010 Jul; 70(8): 589–603 J. Lipid Res. (2022) 63(8) 100213

Membrane Biochemistry 73. Pathogenic membrane associated phosphatidylcholine and sphingomyelin metabolism is linked to skeletal and CNS pathology. DJGPhD.02NOV22. Authentic Biochemistry 02.11.2022 30:00

References J. Lipid Res. (2022) 63(8) 100213 Front. Cell Dev. Biol., 15 October 2019  Bortlein et al. Cell Death & Disease. 2016.  volume 7, page e2488 J. Biol. Chem. 1998;273:14550-14559

Membrane Biochemistry72. DHEA and the steroidogenic pathways as biochemical prolegomena to logical judgments. Dr. Daniel J. Guerra.29.10.22b.Authentic Biochemistry 29.10.2022 29:51

References Dr Guerra's lipid biochemistry lectures Int. J. Mol. Sci. 2019, 20, 4660; doi:10.3390/ijms20194660

Membrane Biochemistry 71. Intracellular-endomembranous cholesterol trafficking and estrogen biosynthesis is under epigenetic control. DJGPhD.29.10.22.Authentic Biochemistry. 29.10.2022 29:55

References Dr Guerra's lipid lectures Periodicum Biologorum 2011. 113(1):43-49 Obstet Gynecol Sci 2014. v.57(2)

Membrane Biochemistry 70. Ketogenesis and cholesterologenesis are mediated by mitochondrial bioenergetics and the ER+Peroxisomal metabolism of VLCPUFA's via membrane domain event ontology.DJGPhD 27.10.2022 29:58

References J Biol Chem v.298(7); 2022 Jul PMC9207681 Antioxidants (Basel). 2021 Jun 3;10(6):906. Dr Guerra lipid lectures

Membrane Biochemistry 69. Distilled electrochemical potential mediated Inner mitochondrial membrane redox and the introduction to sterol involvement.DJGPhD.27.10.22. Authentic Biochemistry 27.10.2022 30:00

Dr. Guerra's Basic Biochemistry Lecture notes

Membrane Biochemistry 68. Elevatum Hypostasis. Dr Daniel J. Guerra. 22.10.22b Authentic Biochemistry 22.10.2022 29:58

Necessary and sufficient knowledge eo ipso obtaining the communicated telos.

Membrane Biochemistry 67. VDAC oligimerization inhibition can block mitochondria-mediated apoptosis and NLRP3 inflammasome activation. DJGPhD.22.10.22.Authentic Biochemistry. 22.10.2022 29:59

References Immunity 2022 551370-1385.e8DOI: (10.1016/j.immuni.2022.06.007 J Biol Chem. 2016 Nov 25; 291(48): 24986–25003. J of Visualized Experiments . 2013; (81): 50966

Membrane Biochemistry 66. Staph aureus infection, autoimmune disease, biliary cholangitis, and neurodegeneration involve NLRP3 Inflammasome activation with core bioenergetic involvement. DJGPhD. 21.10.2022 29:57

References Dr Guerra's immunology lecture notes J Vis Exp . 2013; (81): 50966 Front Immunol. 2019; 10: 1309. Infect Immun . 2013 Dec; 81(12): 4478–4489. Immunity 2022. Volume 55 Issue 8 Pages 1370-1385.e8

Membrane Biochemistry 65. The integration of pro-inflammatory signaling from a plenum of molecular membranous events: The NRLP3 Inflammsome. DJGPhD. 19.10.22. Authentic Biochemistry. 20.10.2022 29:43

References Dr Guerra's Immunology lectures Am J Gastroenterol. 2004 Nov;99(11):2147-9. Front Immunol. 2019 Jun 7;10:1309 Nat Rev Gastroenterol Hepatol. 2019 Dec 9 I mmunity Volume 55 Issue 8 Pages 1370-1385.e8 (August 2022) DOI: 10.1016/j.immuni.2022.06.007

Membrane Biochemistry 64. Prelude to Biochemical Metaphysics and the Mitochondrial Membrane Damage Response I. Dr. Daniel J. Guerra.18.10.22.Authentic Biochemistry Podcast 18.10.2022 29:13

References Dr. Guerra's lecture notes I mmunity 2022. Volume 55 Issue 8 Pages 1370-1385.e8.

Membrane Biochemistry 63. The TCR:APC Chemokine receptor Trigger for Cytokine Stimulation. DJGPhD. 16 Oct 2022 Authentic Biochemistry Podcast 17.10.2022 29:51

References Dr Guerra's membrane immune synapse lectures Al-Aghbar, M.A., Jainarayanan, A.K., Dustin, M.L. et al. The interplay between membrane topology and mechanical forces in regulating T cell receptor activity. CommunBiol 5, 40 (2022). https://doi.org/10.1038/s42003-021-02995-1 Dinkel BA, Kremer KN, Rollins MR, Medlyn MJ, Hedin KE. GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXC...

Membrane Biochemistry 62. The T cell receptor mechanism II. Dr. Daniel J. Guerra. 14.10.22 Authentic Biochemistry 15.10.2022 29:47

Al-Aghbar, M.A., Jainarayanan, A.K., Dustin, M.L. et al. The interplay between membrane topology and mechanical forces in regulating T cell receptor activity. CommunBiol 5, 40 (2022). https://doi.org/10.1038/s42003-021-02995-1 Dr Guerra Membrane lipid lectures

Membrane Biochemistry 61. The Tcell membrane :APC synapse I. Dr Daniel J. Guerra 13.10.22 Authentic Biochemistry 13.10.2022 29:14

References Al-Aghbar, M.A., Jainarayanan, A.K., Dustin, M.L. et al. The interplay between membrane topology and mechanical forces in regulating T cell receptor activity. CommunBiol 5, 40 (2022). https://doi.org/10.1038/s42003-021-02995-1 Seminars in Immunology Volume 13, Issue 2 , April 2001, Pages 129-138

Membrane Biochemistry 60. Human neocortical membrane lipid evolution and the links to cognition,fasting, and neurodegeneration. Dr Daniel J. Guerra. 03Oct2022.Authentic Biochemistry. 04.10.2022 29:55

References Dr Guerra's membrane lipid lectures Neuron 2015. Volume 85, Issue 4.Pages 695–702

Membrane Biochemistry 59. Back to the Basics.Dr Daniel J. Guerra 30 September 2022.Authentic Biochemistry 01.10.2022 29:49

Referewnce Guerra basics lecture

Membrane Biochemistry 58. Cardiolipin biosynthesis involves a PC-linoleic acid requiring maturase and a unique phosphatidylglycerol phosphate phosphatase. DJGPhD.25.9.22.Authentic Biochemistry 26.09.2022 29:59

References Dr Guerra membrane lectures Cell Metab. 2020 Dec 1;32(6):981-995.e7 PNAS  2011.108 (29) 11860-11865 J. Dev. Biol. 2020, 8(2), 10. Chem & Phys of Lipids.2000. June. 106:1-29

Membrane Biochemistry 57. c-Fos osteoclastogenesis and control over acetyl ceramide mediated apoptosis.Dr Daniel J.Guerra.22.9.22 Authentic Biochemistry 22.09.2022 27:51

References Dr Guerra Tumor lectures Nature Reviews Endocrinology 2020.volume 16, pages224–233 J Neurochem. 2006 Nov;99(4):1237-50. doi: 10.1111/j.1471-4159

Membrane Biochemistry 56. Membrane Associated Cholesterol hydroxylation leads to bile acid conjugate- promoting human breast cancer stem cell proliferation. DJGPhD.19.9.22 Authentic Biochemistry. 20.09.2022 29:59

References Dr Guerra's membrane sterol  lecture notes Cells. 2019 Apr; 8(4): 293.

Membrane Biochemistry 55. A phosphoglycerolipid primer. Dr Daniel J. Guerra. Authentic Biochemistry Podcast. 16 Sept. 2022. 17.09.2022 29:59

References  Dr Guerra's Lecture notes