Answers from the Lab

William Morice, II, M.D., Ph. D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., discuss herd immunity and COVID-19.

(00:47)  Can you tell us a little bit about yourself and how your role has changed since COVID-19?   (02:02)  How do you feel that testing will help Mayo and hospitals respond to this coming season's challenge?   (03:38)  Can you tell us a little bit about the algorithm and how it helps to address perhaps potential resource shortages, knowing that we probably can't test everyone for everything all...

William Morice, II, M.D., Ph. D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., review the testing options currently available to detect COVID-19.

(00:45)  Could you just provide our listeners with a little bit of information about you and your background?    (01:00)  The laboratory recently made some updates to this testing for minimal residual disease. Can you just give us a brief overview of that assay?   (03:22)  So these patients go through these treatments, and at what point do they really need this testing, or when should it be consid...

Resources: https://www.cdc.gov/coronavirus/2019-ncov/community/large-events/considerations-for-events-gatherings.html

Speaker 1: (00:39)  Can you start by sharing a little bit about yourself and your expertise for our listeners?     Speaker 1: (01:12)  We're in this pandemic with COVID-19, and I'm hearing about people having hematologic responses to COVID-19. Can you tell us a little bit about what these responses are?   Speaker 2: (04:53)  Here at Mayo Clinic, do we have an assay or a testing profile that could...

William Morice, II, M.D., Ph. D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. With a surge in new cases happening now, and flu season coming soon, Dr. Morice and Bobbi Pritt, M.D., discuss the importance of continuing to follow safety precautions to...

Speaker 1: (01:20)  Today we want to talk about the MDM2 gene amplification assay. Can you give us a little bit of an overview of that test?    Speaker 1: (02:16)  Is there a certain subset of patients that should have this testing, and when should it be performed on those patients?   Speaker 1: (02:50)  So for those patients then, are there any other alternative test options that are available fo...

Full Show Notes: Speaker 1: (00:49) Can you share a little bit about yourself and how your role has changed since COVID-19 started?   Speaker 1: (01:52)  What kind of shortages have you seen in our laboratories? And maybe you could tell us a little bit about some innovative solutions your team's been working on to combat those shortages.   Speaker 1: (04:41)  Have you seen shortages in other areas...

William Morice, II, M.D., Ph. D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the "Answers From the Lab" podcast for his weekly leadership update. In this episode, Dr. Morice and Bobbi Pritt, M.D., explain the difference between collecting a specimen sample at home to be used for COVID-19 testing versus performing a C...

Resources: https://pubmed.ncbi.nlm.nih.gov/25502528/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538476/

William Morice, II, M.D., Ph. D., Chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and President of Mayo Clinic Laboratories, joins the Answers from the Lab podcast for his weekly leadership update. On this episode, Dr. Morice joins Dr. Bobbi Pritt to discuss the different forms of masking that are available and which type you should consider based on your state guidelin...

Timestamps Dr. Bobbi Pritt: (00:45)  Can you share a little bit about yourself and how your role has changed since COVID-19?   Dr. Bobbi Pritt: (02:10)  Has there been any additional quality management practices that have been put into place since the start of COVID-19?   Dr. Bobbi Pritt: (04:13)  Do you feel like these practices will continue to be followed going forward? Or do you think that som...

William Morice, II, M.D., Ph. D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and president of Mayo Clinic Laboratories, joins the Answers from the Lab podcast for his weekly leadership update. On this episode, Dr. Morice discusses how we can approach the upcoming flu season, and Bobbi Pritt, M.D., shares the differences between screening and surveillance approaches...

William Morice, II, M.D., Ph. D., Chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and President of Mayo Clinic Laboratories, joins the Answers from the Lab podcast for his weekly leadership update. On this episode, Dr. Morice discusses how we can prepare for the upcoming influenza season and take necessary precautions as we approach Labor Day weekend.

Resources: https://news.mayocliniclabs.com/covid19/  

William Morice, II, M.D., Ph. D., Chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and President of Mayo Clinic Laboratories, joins the Answers from the Lab podcast for his weekly leadership update. On this episode, Dr. Morice discusses how leadership practices have shifted since the onset of COVID-19, the creation of our command center, and how the team has made signifi...

Resources: COVID-19 Resource Center

Timestamps: Speaker 1: (01:03)  Do you want to tell us a little bit for the listeners, what herd immunity is?  Speaker 1: (02:49)  With your immunology background, if you have any thoughts on what would be the ideal way in your mind? Speaker 1: (06:21)  So it does show the power of the immune response, but it is that question of, is it going to be antibodies? Is it going to be T cells? Is it going...

Timestamps: Speaker 2: (01:12)  Where does it all start?  Speaker 2: (04:32)  How many followers have you?  Speaker 2: (05:59)  So what would your advice be to someone who might listen to this and want to follow in your footsteps?  Speaker 2: (10:41)  So you've been doing this now for a long time, 600 cases on your blog, do you have a few favorites?  Resources: Creepy Dreadful Wonderful Parasite B...

01:21  Could you give us the updates on what you see the state of testing to be today?  01:53  What are some of the new things on the horizon? You know, we're hearing about pooling and antigen testing.  08:34  What are your thoughts on that? 

Timestamps: Speaker 1: (01:14)  Can you tell our listeners about the state of testing today?  Speaker 1: (05:14)  You've been posting on Twitter, some really interesting statistics, do you want to share some of those? Speaker 1: (09:46)  Do you have designer masks, Bill, and do you match your outfit for the day? Resources: https://news.mayocliniclabs.com/covid19/

00:44  So can you tell me a little bit about what your normal role was at Mayo Clinic before COVID happened? Then how has that changed as the COVID pandemic started and progressed?  02:06  So, what are some of the current challenges facing the supply chain and what have been some of Mayo Clinic’s strategies to successfully navigate through these evolving supply chain shortages and demands for supp...

(01:01)  Can you tell us how lab testing capacity is in general at Mayo Clinic and across the United States?  (03:34)  We’re trying to balance how we test for the routine stuff, in addition to meeting COVID demands?  (04:40)  How should we be using testing to manage this COVID-19 outbreak?  (06:36)  So the partnership you mentioned, do you want to tell us a little bit more about that? Because it w...

Timestamps: Speaker 1: (01:00) Perhaps you could start off by just telling us how is this test different than the other antibody tests? What is a neutralizing antibody to begin with?  Speaker 1: (02:40)  Can you tell us about the new neutralizing antibody test then and how it came about?  Speaker 1: (03:39)  What did you do specifically to make it a clinical test?  Speaker 1: (04:50)  How many tes...