2030

What happens when you spend three decades perfecting cancer diagnostics without ever taking a dollar of venture money? At Invivoscribe, it means building what Peter Thiel calls a complex coordinated business, the same category he places Apple in, one too slow to mature for VC funding but built to compound for decades. Jeffrey Miller, Founder, CSO & CEO, breaks down how his team uses unsupervis...

Steve Weiss built MuteSix into one of the most competitive performance marketing agencies in the country and sold to Dentsu for a little north of $100M. In this episode, Steve joins Grayson Lafrenz , Founder and CEO of Cadre AI , to get into what agency owners consistently get wrong about AI adoption, why most companies can't point to AI actually showing up in their P&L, and where the real...

Neal Bloom spent a year on the sidelines from 2023 to 2024, passing on nearly every software deal because he couldn't figure out how to underwrite pure SaaS to 100x anymore. That pause pulled him toward hardware, and what he found changed how he thinks about where returns actually come from now. As Managing Partner at Rising Tide Partners, and with roughly 70-80 investments behind him across a...

Zeke Blattler , Co-Founder & CEO of Los Cuernos Wine , is running a two-person company gunning for a $100-300M exit — and his argument for why that's achievable without a large team is one of the more clear-eyed takes on company building you'll hear. With $90 billion in revenue locked inside glass bottles and an aging consumer base, he saw a structural window most incumbents are too sl...

Most boards pressure founders to reduce direct reports as they scale. Elia Wallen took the opposite approach: he manages 15 direct reports while growing Engine past 1,000 employees to a $2.1B valuation, and he eliminated the Chief Product Officer role entirely. His logic: additional management layers slow decision-making when speed matters most. When you build talent density and restructure one-on...