This Week in Virology

TWiV explains the 1953 paper by Watson & Crick proposing a structure for DNA, and the role of Epstein-Barr virus in triggering the autoimmune disease systemic lupus erythematosus. Hosts:  Vincent Racaniello ,  Kathy Spindler , and  Brianne Barker Subscribe (free): Apple Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode Support science education  at MicrobeTV Immune 100  li...

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are dismayed by the changes on CDC vaccine website positively stating the link between autism and vaccination, the finding of wild type poliovirus 1 in Germany, Marburg virus in Ethiopia, decimation of the elephant breeding colony by H5N1 and the first human case of H5N5 influenza virus infection before Dr. Griffin deep dives into r...

Vincent visits Virginia Tech for the CeZAP Symposium and speaks with XJ Meng and Kylene Kehn-Hall about their research on hepatitis E virus and Rift Valley fever virus.   Host:  Vincent Racaniello Guests:  XJ Meng  and  Kylene Kehn-Hall Subscribe (free): Apple Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode Support science education  at MicrobeTV Immune 100  live at the...

In his weekly clinical update, Dr. Griffin and Vincent Racaniello record from the ASTMH meeting in Toronto and discuss continuing avian flu outbreaks, the continued global measles outbreak, the effectiveness of high and low doses of the influenza vaccine before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dash...

TWiV reviews the passing of James D. Watson, the research that showed human papillomaviruses to be present in genital and laryngeal papillomas and in some cervical cancers, and influenza virus infection, shedding and symptoms in a human challenge study. Hosts:  Vincent Racaniello ,  Alan Dove ,  Rich Condit , and  Brianne Barker Subscribe (free): Apple Podcasts ,  RSS ,  email Become a  patron  of...

In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses the link between in utero SARS-CoV-2 infection and poor neurodevelopment outcomes, the use of an mRNA vaccine as an anti-cancer therapy, why one should receive the HPV vaccine, asymptomatic H5N1 isolations in humans, and H5N1 on turkey farms, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RS...

TWiV discusses the impact of vaccinating with Gardasil-9 adult women who are human papillomavirus positive or with confirmed squamous intraepithelial lesions, and human monoclonal antibodies that target the monkeypox virus A35 protein which protect against lethal disease. Hosts:  Vincent Racaniello ,  Alan Dove ,  Rich Condit ,  Kathy Spindler , and  Brianne Barker Subscribe (free): Apple Podcasts...

In his weekly clinical update, Dr. Griffin and Vincent Racaniello ponder the nomination of Casey Means for Surgeon General by President Trump, how mRNA vaccines may enhance effectiveness of check point inhibitor cancer therapies, if viral infection associates with cardiac disease, H5N1 isolation from backyard birds and turkey farms, and the effectiveness of the COVID-19, RSV and influenza vaccines...

TWiV explains studies showing that SARS-CoV-2 mRNA vaccines improve life span of cancer patients on checkpoint immunotherapy, and broad immunity conferred by a vaccine central in A(H5) influenza antigenic space. Hosts:  Vincent Racaniello ,  Alan Dove ,  Rich Condit , and  Kathy Spindler Subscribe (free): Apple Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode Support scie...

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are distressed by the continuing government shutdown, first locally acquired chikungunya virus infection, President Trump’s suggestion for removing aluminum from vaccines, H5N1 isolation from backyard birds and turkey farms, and the suggestion of establishing an alternative to the CDC’s MMWR and asymptomatic measles infections befo...

TWiV reviews continuing US measles outbreak, host and genetic variations that regulate antibody responses to hepatitis C virus, and varicella-zoster reactivation and the risk of dementia. Hosts:  Vincent Racaniello ,  Alan Dove ,  Brianne Barker , and Angela Mingarelli Subscribe (free): Apple Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode Support science education  at M...

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are dismayed by the government shutdown, the firings at the CDC including EIS agents, H5N1 isolation from backyard birds and its stability in raw milk and cheese, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins meas...

TWiV covers a MacArthur Award for Jason McLellan, 2025 Nobel Prizes in Physiology or Medicine, first treatment for Huntington’s Disease, structure of an archael dsDNA virus from head to tail, and discovery of a Legionella phage that explains a determinant of human disease. Hosts:  Vincent Racaniello ,  Alan Dove , and  Jolene Ramsey Subscribe (free): Apple Podcasts ,  RSS ,  email Become a  patron...

In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about Jane Goodall’s death and the Nobel prize in Physiology/Medicine for understanding immune system control before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, if 2 doses of the influenza vaccine...

TWiV reviews experiments to understand infection, pathogenesis, and transmission of avian H5N1 influenza virus in goats, and identification of a cellular receptor for tick-borne encephalitis virus. Hosts:  Vincent Racaniello ,  Alan Dove , and  Brianne Barker Subscribe (free): Apple Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode Support science education  at MicrobeTV P...

In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about the ongoing Ebola outbreak in DRC, increases in screwworm diagnoses, a pertussis death in Mississippi before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, monoclonal antibody therapy against R...

From ESCV 2025, Vincent speaks with Elke Wollants about a project to identify SARS-CoV-2 and other viruses in toilet waste from airplanes. Host:  Vincent Racaniello Guest:  Elke Wollants Subscribe (free): Apple Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode Support science education  at MicrobeTV Laboratory for Clinical and Epidemiological Virology  (KU Leuven) Virologi...

TWiV explains experiments to create genetically modified chickens that are resistant to avian influenza infection, and discovery of combination antiviral therapy for HTLV-1 infection. Hosts:  Vincent Racaniello ,  Alan Dove , and  Rich Condit Subscribe (free): Apple Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode Support science education  at MicrobeTV Creating avian inf...

Vincent travels to Thessaloniki, Greece to attend the 27th meeting of the European Society for Clinical Virology, where he speaks with Pamela Vallely, ESCV President, and Piotr Kramarz, Chief Scientist, European CDC, about the activities of ESCV and ECDC. Host: Vincent Racaniello Guests:  Piotr Kramarz  and  Pamela Vallely Subscribe (free): Apple Podcasts ,  RSS ,  email Become a  patron  of TWiV!...

In his weekly clinical update, Dr. Griffin with Vincent Racaniello lament the anti-vaccine, anti-science composition of the ACIP, US cases of Chagas disease, the Ebola vaccination campaign in the DRC, the death of an infant in LA due to measles complications (SSPE), before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwat...

Vincent travels to Waterville Valley, NH to attend the Harvard virology retreat, where he speaks with Aaron Schmidt, Ben Gewurz, and Tatum Sass about their careers and their research on influenza virus, Epstein-Barr virus, and CAR-T cells. Hosts:  Vincent Racaniello Guests:  Aaron Schmidt ,  Ben Gewurz , and  Tatum Sass Subscribe (free): Apple Podcasts ,  RSS ,  email Become a  patron  of TWiV! Li...

In his weekly clinical update, Dr. Griffin with Vincent Racaniello discuss the continued Legionnaire’s outbreak in Harlem, invasive Asia longhorned tick and associated disease, potential Ebola outbreak in the Congo, Florida ending childhood vaccine mandates, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan...

TWiV re-issues our 100th episode which featured a discussion of viruses with David Baltimore, an exemplary scientist and Vincent’s exemplary mentor, who passed on 6 September 2025. Hosts:  Vincent Racaniello ,  Alan Dove , and  Rich Condit Guest:  David Baltimore Subscribe (free): Apple Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode Support science education  at Microbe...

TWiV reviews a study showing that the 2009 influenza pandemic virus disrupted biennial respiratory syncytial virus epidemics in northern Stockholm, and development of broad-spectrum synthetic carbohydrate receptors that inhibit viral entry of coronaviruses, filoviruses, and paramyxoviruses. Hosts:  Vincent Racaniello ,  Alan Dove ,  Rich Condit ,  Kathy Spindler , and Angela Mingarelli Subscribe (...