The Connect Current

In this episode of The Connect Current, our regular host—James Zanewicz, CEO of Connect—moves to the guest seat for a conversation with Austin Robertson, Connect’s Marketing and Events Coordinator. James looks back on a season of conversations with founders, investors, and ecosystem leaders to give his view of where San Diego’s innovation ecosystem stands today. He also talks about which sectors a...

In this episode of The Connect Current, we sit down with Hala Madanat, Vice President for Research and Innovation at San Diego State University, to explore how universities can play a larger role in helping founders build and scale companies. The conversation dives into SDSU’s growing strengths across AI, National Security, technology, workforce development, and applied research, along with how st...

In this episode of The Connect Current, we sit down with Dr. Garrett Smith and Dr. Nick Mourlas of Reef Haven Ventures to unpack what it really takes to move from strong science to a scalable, investable company. The conversation is built for founders, offering a clear look into how early-stage investors evaluate opportunities, what separates compelling research from a real business, and how teams...

In this episode of The Connect Current, host James Zanewicz sits down with Denise Bevers, Co-founder, President and CEO of VETmAb BIO, to explore what it really takes to build an animal health biotech company in one of the world’s leading innovation ecosystems. Denise brings decades of experience in drug development and company building, and she shares why animal health remains an underexplored bu...

In this episode of The Connect Current, host James Zanewicz sits down with Rupak Doshi, Co-founder and CEO of OmniSync, to explore how better systems can accelerate innovation. Rupak shares how OmniSync is helping founders and organizations navigate funding, market intelligence, and commercialization through AI-powered tools, and why the path from idea to traction is still more fragmented than it...

In this episode of The Connect Current, host James Zanewicz sits down with Debbie Chen, Founder and CEO of Hydrostasis, to explore how nontraditional journeys are shaping the next generation of innovation. Debbie shares how Hydrostasis is advancing hydration science through wearable technology, and why better understanding hydration as a vital sign could unlock new opportunities in health and perf...

In this episode of The Connect Current, host James Zanewicz sits down with Adam Jacobs, President of Xzom, to explore how early disease detection and accessible diagnostics are shaping the future of health innovation. Adam shares how Xzom is building point-of-care solutions designed to make diagnostics faster and more accessible, and what it takes to stand out in a complex, competitive space. Draw...

In this episode of The Connect Current, host James Zanewicz is joined by Courtney Young, PhD, Co-founder and CEO of MyoGene Bio, one of Connect's 2026 Cool Companies. MyoGene Bio is developing MyoDys45-55, an AAV-delivered CRISPR gene editing therapy for Duchenne muscular dystrophy, a rare and devastating muscle wasting disease with no cure. Courtney traces her path from a high school moment, when...

In this episode of The Connect Current, we sit down with Graeme Rae, Ph. D., Founder and CEO of HyperKelp, to explore how the company is turning the ocean into a sensing network. Graeme shares how HyperKelp’s Kelp Smart Buoy is designed as an open marine platform that can carry a wide range of sensors and deliver ocean data in near real time for environmental, commercial, port, and defense applica...

In this episode of The Connect Current, we sit down with James Mackay, Ph. D., President and CEO of Crystalys Therapeutics, to explore how the company is advancing a new treatment path for people living with gout. James shares how Crystalys is developing dotinurad, a next-generation, once-daily oral URAT1 inhibitor, and what the company’s recent $130 million Series B financing enables as it moves...

In this episode of The Connect Current, we sit down with Ramesh Ramji, Founder and CEO of SpectralTx, to explore how spectral hyperplexing technology could help reshape molecular screening and the future of connected data. Ramesh shares how SpectralTx is developing tools like Spectra-Gel and SpELs to improve encoding depth, speed and data fidelity, giving researchers richer information for drug di...

In this episode of The Connect Current, we sit down with Niren Shah, PharmD, MBA, Co-founder and CEO of Cove Therapeutics, to explore one of the biggest challenges in genetic medicine: delivery. Niren shares how Cove is developing non-lipid, non-viral biodegradable polymeric nanoparticles designed to overcome key limitations in the field, including efficiency, safety, manufacturing, redosing, and...

In this episode of The Connect Current, we sit down with Stanley Lewis, MD, MPH, Founder and CEO of A28 Therapeutics, to explore how targeted cancer therapies can create better options for patients facing difficult diseases. Stanley shares the story behind A28’s targeted oncolytic peptide platform, the company’s lead candidate AT-101, and what it takes to move a clinical-stage biopharmaceutical co...

In this episode of The Connect Current, we sit down with Scott Tait to explore how San Diego can better connect national security needs, university research, dual-use startups, capital, and policy into a stronger innovation system. Drawing on his 27-year Navy career and his work across Lumetec, Startup Science, and the National Security Innovation Catalyst at UC San Diego, Scott shares what it tak...

In this episode of The Connect Current, we sit down with Kris Lichter, CEO of TL Foundation, to explore a different approach to investing in innovation. The conversation dives into how TL Foundation is transforming philanthropic capital into long-term investment in San Diego startups, creating an evergreen model that reinvests success back into the region. Kris shares what makes a company a strong...

In this episode of The Connect Current, host James Zanewicz sits down with Abubakar "Abu" Jalloh, Site Director of BioLabs San Diego, to explore the infrastructure, community, and support systems that help life science startups move faster. Abu shares how BioLabs San Diego helps early-stage biotech companies access lab space, equipment, operational resources, and strategic connections without the...

In this episode of The Connect Current, host James Zanewicz sits down with Gian Luca Araldi, PhD, PharmD, MBA, PMP and Founder/CEO of Avanti Biosciences, to explore the challenge of developing new therapies for fibrotic diseases and what it takes to advance promising science toward the clinic. Gian Luca shares how Avanti Biosciences is developing novel small-molecule therapies for conditions like...

In this episode of The Connect Current, host James Zanewicz sits down with Trevor Laudate, Co-Founder of Ecodrive, to explore how businesses can turn everyday customer actions into measurable environmental impact. Trevor shares how Ecodrive helps companies connect purchases, bookings, signups, and other customer interactions to verified sustainability initiatives, making it easier to create meanin...

In this episode of The Connect Current, host James Zanewicz sits down with Ivana Mikić, PhD, CEO of Sarpeda Inc., to explore how AI is helping researchers unlock more value from the biological imaging tools they already use. Ivana shares how Sarpeda is using AI-powered software to improve fluorescence microscopy, reduce imaging challenges, and extract more biological information from existing rese...

In this episode of The Connect Current, we sit down with Aadeel Akhtar, Founder and CEO of Psyonic, to explore how advanced robotics and human-centered technology are reshaping the future of prosthetics and mobility. The conversation dives into Aadeel’s journey from research and engineering into company building, the mission behind Psyonic’s work, and how innovation can create more accessible, res...

In this special episode of The Connect Current, Tre Braquet flips the script and interviews Connect CEO James Zanewicz about the vision behind Connect 3.0 and the future of San Diego’s innovation ecosystem. The conversation explores how Connect is evolving beyond events to become a front door, connective platform, and amplification engine for founders, investors, universities, companies, and civic...

In this episode of The Connect Current, we sit down with Mike Krenn, Managing Director of Prebys Ventures, to explore what investors are really looking for in founders and early-stage companies. The conversation dives into how Prebys Ventures is approaching investment in San Diego’s innovation economy, what makes a company truly investable, and where founders most often struggle when raising capit...

In this episode of The Connect Current, we sit down with Hala Madanat, Vice President for Research and Innovation at San Diego State University, to explore how universities can play a larger role in helping founders build and scale companies. The conversation dives into SDSU’s growing strengths across AI, National Security, technology, workforce development, and applied research, along with how st...

In this episode of The Connect Current, we sit down with Will Bright, Founder and CEO of Saferide.ai, to explore how personal experience can shape meaningful innovation. Will shares the journey that led to building a company focused on safety and mobility, and how lived insight can translate into real world solutions. The conversation highlights what it takes to turn an idea into action, the chall...

In this episode of The Connect Current, we sit down with Holly Smithson, CEO of Athena, to explore how leaders are navigating one of the largest workforce transformations in decades. As AI rapidly reshapes how work gets done, Holly shares what it takes to upskill teams, stay competitive, and lead responsibly through change. The conversation dives into where organizations are falling behind, what e...