The Aging Science Podcast by VitaDAO

In this episode of the Aging Science Podcast by VitaDAO, we explore the connection between environmental pollution and longevity with Dr. Dushani Palliyaguru. Delve into the Nrf2 pathway, a critical mechanism for cellular defense, and discover the benefits of sulforaphane from broccoli as a potent Nrf2 activator. Dr. Palliyaguru, a renowned expert in aging and disease prevention, shares her extens...

In this episode of The VitaDAO Aging Science Podcast, we uncover the secretive yet pivotal rapamycin study led by Prof. Adam Salmon. Prof. Salmon, a prominent figure in aging research, shares his insights into AMPK, caloric restriction (CR) mimetics, and multistress resistance in aging. We explore the challenges and promises of invertebrate models and discuss the groundbreaking marmoset study inve...

In the current episode of The VitaDAO Aging Science Podcast, we dive into the intricate world of rapamycin, caloric restriction, and inflammaging with the distinguished Dr. Arlan Richardson. Dr. Richardson, a pioneer in aging research with a career spanning over five decades, shares his extensive knowledge and groundbreaking insights. We discuss his pioneering work on rapamycin, the complexities o...

In the current episode of The VitaDAO Aging Science Podcast, we explore the fascinating intersection of entropy, epigenetics, and aging with our esteemed guests, Peter Fedichev, founder of Gero and a trailblazer in longevity research, and Prof. Jan Gruber from Yale-NUS, known for his deep understanding of the physics behind aging. As we navigate through Peter Fedichev's recent paper that spark...

In the upcoming episode of The Science of Aging Podcast, we dive deep into the critical questions surrounding mouse models in aging research with our special guest, Dr. Dan Ehninger from the German Center for Neurodegenerative Diseases (DZNE) in Bonn. Dr. Ehninger, a visionary in the field of biogerontology, brings to the table his controversial and thought-provoking perspectives on the limitation...

n this episode of The VitaDAO Aging Science Podcast, we're excited to host Prof. Rudolf Wiesner, an esteemed figure in the field of mitochondrial biology. As a key member of the CECAD Research Center at the University of Cologne, Prof. Wiesner's research has significantly advanced our understanding of mitochondrial dysfunction and its impact on aging. In our conversation, we'll explore...

In this episode of The VitaDAO Aging Science Podcast, we are thrilled to welcome Prof. Björn Schumacher, a leading expert in genome stability and aging. As Director of the Institute for Genome Stability in Ageing and Diseases at the University of Cologne, Prof. Schumacher has pioneered research into how DNA damage influences the aging process and the development of age-related diseases. We'll...

In the upcoming episode of The Science of Aging Podcast, we're set to explore aging research with Dr. Jesse Poganik and Dr. Mahdi Moqri, just before the 2023 Biomarkers of Aging Symposium. Dr. Poganik from Brigham and Women's Hospital and Harvard, and Dr. Moqri, a joint fellow at Harvard and Stanford, will share insights on biomarkers and omics in longevity studies. We'll discuss the i...

In this installment of The VitaDAO Aging Science Podcast, we embark on a journey through the complex terrain of human genetics and aging with Dr. Joris Deelen. Broadcasting from the dynamic setting of the ARDD conference in Copenhagen, we dive into a rich and enlightening conversation about the limitations and revelations of using mice as model organisms in aging research. Dr. Deelen, a renowned r...

In this episode of The VitaDAO Aging Science Podcast, we delve into the intricate dance of time and biology with Dr. David Meyer and Prof. Sarah Voisin. As we broadcast from the vibrant atmosphere of the ARDD conference in Copenhagen, we engage in a thought-provoking dialogue about the ticking of the epigenetic clock and the adaptive changes that come with aging. Dr. Meyer, a bioinformatician with...

In this episode of The VitaDAO Aging Science Podcast, we embark on a fascinating journey through the realms of longevity and cellular health with Dr. Arwen Gao. Dr. Gao, a leading authority in the fields of aging research, metabolism, and lysosomal pathways, takes us on a deep dive into the science behind extending lifespan. We'll explore the secrets of C. elegans, the tiny worm with big insig...

In this episode of The VitaDAO Aging Science Podcast, we delve into the world of age-related eye diseases with Prof. Dorota Skowronska-Krawczyk, a renowned expert in vision and aging. We explore fundamental aging mechanisms, challenges in research, and the potential of senolytics for eye conditions. Prof. Dorota shares insights into the retina's mysteries, the eye's unique immune status, a...

In this enlightening episode of the Aging Science podcast, we dive deep with Prof. Vera Gorbunova, a trailblazer in the realm of longevity and aging research. Our discussion spans a myriad of fascinating topics, from the mysteries of genome stability and the unique biology of naked mole rats to the promising role of hyaluronan in cancer prevention. We explore the groundbreaking findings on SIRT6 a...

In this episode of the Aging Science podcast, we engage in a thought-provoking conversation with Prof. Joao Pedro De Magalhaes (@jpsenescence). Our dialogue covers a wide array of subjects, including the philosophical and scientific aspects of aging research, the potential of transhumanism, and the intriguing concept of cryonics. We delve into the repurposing of drugs for longevity, the phenomenon...

In this episode of the Aging Science podcast, we delve into an insightful discussion with Dr. Heidi Pak (@pak_heidi). Our conversation spans various topics, such as the distinction between fasting and time-restricted feeding, the influence of caloric restriction on different mouse strains, sleep cycles, and the challenges of grad school. We also explore the healthspan vs lifespan debate, the futur...

In this episode of the Aging Science podcast we talked with Prof. Nir Eynon (@nir_eynon). We touched on many topics, including elite athletes, how COVID affected working culture (for the better), the benefits of tabatas, epigenetic and muscle clocks and how they are affected by exercise, biases in research and the role of meta-analysis.

We had a marvelous conversation with Assoc. Prof. Viktor Korolchuk (@VIKorolchuk) about autophagy, mitochondria, senescence, the importance of modelling, and human desire for radical lifespan extension. Originally from Ukraine where he received his Ph. D., Viktor worked in Cambridge as a postdoctoral fellow and later moved to Newcastle upon Tyne in the beautiful north of the UK to pursue his work...

Slowing aging by a couple of percents would save more money than curing any single disease, be it cancer, heart disease, or diabetes. Aging is, in fact, the major risk factor that all these diseases have in common. For this reason, slowing aging becomes the most efficient path to a sustainable and healthy future for humanity. To get this message out we started The Aging Science podcast. We will br...

In this podcast, I (@aging_scientist) spoke with Dr. Rich Miller about the ins and outs of mouse aging. The topics we discussed, roughly in this order, included the Interventions Testing Program, rapamycin, mecilizine, and other lifespan-extending drugs. We talked about the importance of genetically heterogenous mouse stocks and the issues with fast-aging progeroid mouse models. We also covered hi...