Conversations in Equine Science

In this episode Nancy McLean reviews a Tnibar (2025) literature review with seven equine studies showing 2.5% polyacrylamide hydrogel (IPAAG) provides long‑lasting, biocompatible intra‑articular relief for osteoarthritis, often reducing or resolving lameness from one month up to 24 months in many horses. The episode summarizes study outcomes, notes rapid onset in some horses (as early as one week)...

This episode reviews cases of steroid-induced laminitis and examines recent research and owner-reported experiences using SGLT2 inhibitors (most commonly ertugliflozin) as an off-label treatment for equine metabolic syndrome and hyperinsulinemia-associated laminitis. An online survey of 342 owners found most horses treated with SGLT2Is showed improved quality of life and reduced pain, with many ho...

Updates on preliminary research findings on steroid use and insulin deregulation in horses.

This episode explores whether horses can experience headaches by examining cervical spine pain, common signs like head rubbing or altered carriage, and how musculoskeletal and nervous system issues contribute to discomfort. Nancy reviews diagnostic options, treatment and rehabilitation strategies, and the need for improved imaging and physiotherapy to restore performance and well-being. Research L...

In this episode Nancy McLean answers listener emails about geldings that chew lead ropes and reins, she explains how cortisol and the HPA axis relate to stress-driven behaviors, and describes how consistent training, handler calmness, routines, turnout, and nutrition can help horses down-regulate stress. The episode also summarizes research on cortisol sampling methods (plasma, saliva, hair) for s...

In this episode Nancy McLean explores a listener question about whether to remount after a fall, using Dr. Stephen Peters’ research and a review by McBride et al. to explain how equine learning, myelination, and long-term potentiation shape behavior. Nancy explains how automaticity, basal ganglia consolidation, and dopamine-driven rewards can help overwrite fearful responses, and she shares...

The core of the equine brain’s emotional center, Nancy describes how the neurological processes of the limbic system take place. She also highlights the reward prediction error (RPE) and the impact it has on equine learning.

This is a continuation of our study on Equine Neurology and Ethical Horse Training and Management.

In this episode Nancy McLean explores Dr. Stephen Peters' book Horse Brain Science, comparing human and equine brain anatomy and function. She explains brain size and cortical folding, then walks through the four main lobes (frontal, parietal, temporal, occipital), the amygdala and hippocampus, and the brainstem. The episode connects these brain differences to horse behavior and training—why...

This episode introduces equine neurobiology through the work of Dr. Stephen Peters, explaining core concepts like neurons, neurotransmitters, neuroplasticity, and how sensory processing affects learning and behavior. It shows how applying neuroscience can reduce stress, build trust, and improve training and welfare, and previews a follow-up episode on brain anatomy.

In this episode Nancy talks about using a grinder for hoof trimming. Ida Hammer teaches online and in person Hoofcare classes. Check her website out at www.mackinawdells2.com

This episode reviews a 2019 study where 23 horses were trained to use symbols to indicate whether they wanted a blanket put on, left on, or removed. Researchers tested horse choices across a range of temperatures, wind, rain, and seasons to see how weather and individual factors influenced blanket preference. Key findings: horses overwhelmingly chose blankets at very low temperatures (below −10°C/...

In this episode Nancy McLean checks into recent equine herpes cases and focuses on new research linking corticosteroid (triamcinolone) joint injections to insulin spikes and severe laminitis. They review the case of Fiona, a competitive mare who developed fatal laminitis after sacroiliac injections, and summarize ongoing studies at NC State funded by the Chromatic Fund. The researchers are compari...

This episode breaks down the current EHV-1 (EHM) outbreak in the U.S., covering clinical signs, transmission, and incubation periods. Listeners will learn about vaccine limitations, why quarantine and low-stress management matter, and practical biosecurity measures—cleaning, disinfectants (70% alcohol, hydrogen peroxide, chlorhexidine), and when to avoid bleach on dirty surfaces. Advice emphasizes...

Hosts Nancy McLean and Kate Acton discuss a 2025 study on how owner–veterinarian interactions affect recognition and management of pain in horses, using owners’ stories and vets’ perspectives to highlight subtle behavioral signs and practical decisions. The episode emphasizes the importance of knowing each horse’s normal behavior, keeping compassionate communication open wi...

Nancy and Kate conclude their discussion on the current research and the Flying Lead Change book by Kelly Wendorf. Sign up for the Kelly Wendorf clinic at the InStride episode page link.

Nancy and Kate discuss identifying and measuring the emotional states of horses. Link to research: https://doi.org/10.1093/tas/txaf033 Book by Kelly Wendorf: Flying Lead Change. Instride Podcast: https://podcasts.apple.com/us/podcast/in-stride/id1602148957

In this episode of Conversations in Equine Science, Kate and Nancy explore a compelling research paper titled "Retirement Risk Factors, Exercise Management, and Muscle Mass in U.S. Senior Horses" by Elisa Herbst. Published in May 2023, this paper dives into the intricacies of managing the health and exercise of senior horses in the U.S., examining factors such as retirement risk, exercise routines...

This episode Kate and Nancy discuss a scoping review of 46 research papers on the effects of horseshoe type on equine gait. Open Access Research Reference/Link: Aoun, R., Takawira, C., & Lopez, M. J. (2025). Horseshoe effects on equine gait-A systematic scoping review. Veterinary surgery : VS, 54(1), 31–51. https://doi.org/10.1111/vsu.14162

This week Kate and Nancy discuss rider back pain and it's association with 3 different stirrup lengths and 2 rider positions. Research Reference: Keener, Michaela M.1; Critchley, Meghan L.1; Layer, Jacob S.1; Johnson, Evan C.1; Barrett, Steven F.2; Dai, Boyi1. The Effect of Stirrup Length on Impact Attenuation and Its Association With Muscle Strength. Journal of Strength and Conditioning Research...

This week Nancy and Kate discuss the new movie produced by Sue Dyson. Watch the movie at the link below. https://youtu.be/3ulkLHqHZ3g?si=Xla9VAal6ilL85sm

Nancy and Kate discuss a research paper on adjusting human craniosacral therapy to horses. Reference: Kanik, W.; Augustyn, J.; Tombarkiewicz, B. Adapting Craniosacral Therapy to Treat Horses. Acta Vet. Brno 2017, 86, 75–84. https://actavet.vfu.cz/media/pdf/actavet_2017086010075.pdf Article Link: https://www.equinecraniosacral.com/articles/hands-on-light-touch.pdf

This week Kate and Nancy discuss the habit loop of cue-routine-reward and the benefits that horses derive from its formation. Research Reference/Link: White, J.; Sims, R. Improving Equine Welfare through Human Habit Formation. Animals 2021, 11, 2156. https://doi.org/10.3390/ani11082156

This week Nancy and Kate discuss a just published research paper on the complex cognitive abilities of horses. Research Reference: Louise Evans, Heather Cameron-Whytock, Carrie Ijichi, Whoa, No-Go: Evidence consistent with model-based strategy use in horses during an inhibitory task, Applied Animal Behaviour Science, Volume 277, 106339, SSN 0168-1591, Link: https://www.sciencedirect.com/science/ar...