UC San Diego (Video)

Blood-forming stem cells replenish the blood and immune system, making them important targets for gene therapy and transplantation. Cynthia Dunbar, M.D., explains how genetic barcodes let scientists track individual stem cell clones over time. Long-term studies in nonhuman primates reveal stable contributions from blood stem cells and unexpected persistence among certain natural killer immune cell...

A vocalist of extraordinary emotional power and authenticity, Daneen Wilburn opens the fall Intersections Concert Series with an evening rooted in gospel tradition, soul expression, and personal testimony. Having performed since childhood, Wilburn brings a voice shaped by both spiritual tradition and lived experience. Her celebrated return to the stage after raising her family has made her one of...

Photography makes environmental changes visible that are difficult to recognize in everyday life. James Balog, Founder and Director of the Earth Vision Institute, describes his shift from celebrating nature’s beauty to documenting how human activity reshapes the planet. His photographs range from endangered wildlife and towering trees to mines, wildfires, and the atmosphere above Earth. Through th...

Kristin Hannah is an award-winning and bestselling author of more than 20 novels, including The Nightingale. Her 2024 novel, The Women, is a historical fiction about female nurses in the Vietnam War. Hannah wrote it during the Covid pandemic lockdown, seeing similarities to the nation's political division of the Vietnam era. A theme of Hannah's writing is the marginalization of women and the power...

Heart repair is moving beyond a single strategy. Catriona Jamieson, M.D., Ph. D., Ehtisham Mahmud, M.D., FACC, FSCAI, Eric Adler, M.D., Karen Christman, Ph. D., and set designer Robert Brill discuss approaches to preventing and repairing heart damage. Mahmud describes a model linking cardiovascular care, training and clinical research. Adler explains how patient skin cells can be turned into beati...

As we age, experiences of loss often become more common, but so can our capacity for resilience. Danielle Glorioso, executive director of the Stein Institute for Research on Aging, explores the psychological and emotional processes that help older adults adapt to bereavement and other significant life losses. Drawing on current research and clinical insights, participants will learn how resilience...

Vaginal microbiome research may offer new ways to understand infections, fertility, preterm birth and other areas of women’s health. Pita Navarro, co-founder and chief scientific officer of Evvy, joins Cynthia Gyamfi-Bannerman, M.D., M.S., of UC San Diego Health, to explain how patient-contributed samples and health information can support research and product development. Navarro describes Evvy’s...

Gladys (Sandy) Ramos, M.D., is a UC San Diego Health perinatologist and professor who cares for patients with complex pregnancies, including those affected by diabetes. She explains how immigrating from Peru, learning from her grandmother and wanting to serve Spanish-speaking communities shaped her work. Ramos also describes feeling out of place in college and not getting into medical school on he...

Social isolation may influence how the body recovers from pelvic floor injury after childbirth. Lindsay Burnett, M.D., Ph. D., assistant professor and physician-scientist at UC San Diego, studies factors during pregnancy and postpartum that may affect pelvic floor muscle recovery, including medications, diet, exercise and social interaction. Her research grew from clinical observations connecting...

Grecia Paola Siono Gutierrez and Jose Enrique Siono Gutierrez share how family, mentorship and community shaped their path from Mexicali to studying electrical engineering at UC San Diego. The siblings describe beginning at community college, transferring together and adjusting to classrooms where they often saw few students who shared their background. Grecia discusses finding support through the...

Mechanical forces may help the body coordinate pregnancy and labor. Yunxiao Zhang, Ph. D., of Scripps Research Institute, examines how PIEZO1 and PIEZO2, proteins that open in response to stretch, contribute to uterine contractions and the timing of birth. Zhang finds PIEZO1 in uterine smooth muscle and PIEZO2 in sensory nerve fibers around the cervix. In mouse models, removing both channels weake...

RNA damage, mentorship and the realities of building a career in science come together in Alex Chaim's work and personal journey. Chaim, principal investigator of the Chaim Lab and assistant professor of cell and developmental biology at UC San Diego, studies whether damage to RNA may contribute to diseases associated with oxidative stress, including neurodegeneration. He also reflects on finding...

Utilitarianism affects law, public policy, and social justice in important ways. Professor Peter Bolland explains how Jeremy Bentham and John Stuart Mill’s focus on the greatest good for the greatest number shaped modern ethical decision-making. Bolland examines women’s rights, LGBTQ+ rights, and animal welfare, helping clarify how Utilitarian ideas influence debates about justice and equality. Th...

Menopause care is changing as more patients seek evidence-based guidance for symptoms, prevention, and long-term health. Kathryn Macaulay, M.D., M.S.C.P., F.A.C.O.G., UC San Diego Health, and Rajita Patil, M.D., M.S.C.P., F.A.C.O.G., UCLA Health, explain why many people still struggle to find trained care, even as menopause affects sleep, mood, work, genitourinary health, and cardiometabolic risk....

U.S.-China relations affect global stability in important ways. Graham Allison, Professor of Government at Harvard Kennedy School, explains how the Thucydides’ Trap shapes the challenge of managing competition between the two countries. Allison examines strategic stability, the Xi-Trump summit, and the promise and limits of a new paradigm for major-country relations, helping clarify whether the U....

Climate change is fundamentally altering marine environments worldwide. But what does this mean for the creatures that call the ocean home? Join Martin Tresguerres, Ph. D., as he delves into the work of the Allen Discovery Center for Neurobiology in Changing Environments (ADC-NiCE), where researchers are working towards answering this question. Through a combination of neurobiology, physiology and...

Cardiovascular disease is a major threat to maternal health during pregnancy and the peripartum period, particularly for women with preexisting heart conditions. A UC San Diego cardiologist describes the development of a multidisciplinary cardio-obstetrics initiative designed to coordinate care for patients with congenital heart disease, heart failure, arrhythmias and coronary artery disease. The...

AI-powered cell imaging may help researchers identify biological differences that are difficult or impossible to see by eye. Yu-Hwa Lo, Ph. D., and Louise Laurent, M.D., Ph. D., describe a system that combines high-speed imaging, cell sorting, microfluidics, and artificial intelligence. The technology creates label-free images of cells, uses AI to classify them, and can isolate selected cells for...

Continuous glucose monitoring and wearable data are changing how researchers study pregnancy and women’s health. Gladys (Sandy) Ramos, M.D., explains why glucose control is difficult during pregnancy and how CGM can reveal patterns that finger-stick testing may miss. She also describes research on CGM use in type 2 and gestational diabetes, labor, and behavior change. Ben Smarr, Ph. D., shows how...

For people diagnosed with cancer, patient advocacy can play a vital role throughout the treatment process. At UC San Diego’s annual Prostate Cancer Patient Summit, keynote speaker and three-time MLB All-Star David Justice brought visibility and purpose to that message, underscoring the broad reach and lasting importance of speaking up for patients and families. [Health and Medicine] [Show ID: 4164...

Drawing from her remarkable life journey and her memoir, Conquering Me: A Memoir of Courage, Faith, and Transformation, pastor and author Jolinda Wade shares powerful reflections on overcoming adversity, embracing purpose, and the mentors, opportunities, and communities that help shape our futures. The mother of NBA Hall of Famer Dwyane Wade, she talks about how, before becoming an advocate for pe...

Topology offers a way to organize complex data by looking for shape, structure, and relationships. Yusu Wang, Ph. D., UC San Diego, and Gunnar E. Carlsson, Ph. D., Stanford University, discuss how ideas from algebraic topology move from pure mathematics into data science, machine learning, and AI. Carlsson explains why topological data analysis helps identify meaningful groups in large data sets,...

Alzheimer’s disease can begin developing years before memory and thinking problems become noticeable. Iris Broce-Diaz, Ph. D., of UC San Diego is developing accessible, noninvasive, and cost-effective tools to help primary care physicians and neurologists identify people at higher risk earlier. Her models combine information from cognitive assessments, brain imaging, genetics, and PET scans to est...

Men with non-obstructive azoospermia may undergo microscopic testicular sperm extraction, or mTESE, without knowing whether sperm will be found. Kun Tan, Ph. D., of UC San Diego explains how molecular semen analysis could provide a noninvasive way to predict the procedure’s outcome. The assay uses stage-specific germ cell markers identified through single-cell RNA sequencing, then measures those m...

Archaeology can help communities understand environmental change, protect cultural heritage, and prepare for an uncertain climate future. Isabel C. Rivera-Collazo, Ph. D., of UC San Diego studies relationships among people, oceans, coastal ecosystems, and climate in Puerto Rico and the Caribbean. She explains how Hurricane Maria shifted her research from identifying theoretical vulnerabilities to...