Kyle O'Brien
State Change
It’s time we rewrite the social contract for the 21st century. State Change is a cinematic podcast hosted by Kyle O'Brien https://x.com/analog_kyle Join us on YouTube : https://www.youtube.com/@JoinStateChange (https://www.youtube.com/@JoinStateChange)State Change on social media@JoinStateChange (https://www.youtube.com/@JoinStateChange) on X/twitter, Instagram, Tik Tok, linkedinHosted on Ausha. See ausha.co/privacy-policy for more information.
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State Change EP3 - Reprogramming Life Itself with Germline Gene Editing 16.12.2025 1:12:03
What happens when biology begins moving at the speed of software? In this episode, Kyle O’Brien sits down with Cathy Tie, founder & CEO of Manhattan Genomics, to explore the frontier of germline gene editing— a technology that could one day eliminate inherited disease, reshape reproduction, and redefine what it means to be human. Germline editing is the most controversial topic in science toda...
The Prospect of Immortality 13.11.2025 1:39:05
Is Death just a Technical Problem we haven’t solved yet? In this episode of State Change, Kyle O’Brien sits down with Emil Kendziorra, founder of Tomorrow Bio, to explore the science, ethics, and future of cryopreservation - the process that may one day allow humans (and even pets) to be revived centuries from now. We talk about the brain, identity, consciousness, why people fear death, and what...
The Internet’s Connective Tissue 21.10.2025 55:51
Technology moves exponentially while society moves linearly. This divergence shapes everything from our sense of identity to the architecture of trust online. In the first episode of State Change, Kyle O’Brien speaks with Arthaud Mesnard, founder of mio.xyz , about portable identity, self-sovereignty, and what happens when AI begins to act on our behalf. It's time we rewrite the social contract fo...
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