Progress, Potential, and Possibilities Podcast / Show

Send us Fan Mail Most autoimmune drugs suppress the immune system broadly - but what if you could selectively remove the antibodies actually causing disease? That’s exactly what VYVGART is doing, and it may fundamentally change how we treat conditions like myasthenia gravis and CIDP. Dr. Luc Truyen, M.D., Ph. D., is Chief Medical Officer at argenx ( https://argenx.com/ ), where he leads the compan...

Send us Fan Mail In the time it will take you watch this episode, over 2,000 people around the world will die from diseases driven by arterial plaque. But what if we could actually remove the toxic cholesterol already trapped inside arteries? Today we’re diving into one of the biggest unsolved problems in medicine and aging: how do you actually remove arterial plaque instead of merely slowing its...

Send us Fan Mail One of the biggest drivers of hospital admissions isn’t what most people think - it’s fluid. Not infection, not surgery…fluid overload. And when the body stops responding to diuretics, medicine runs into a wall. Today we’re exploring one of the most challenging and underappreciated frontiers in hospital medicine: fluid overload and the cardiorenal continuum - where heart failure a...

Send us Fan Mail Pharma has only explored a tiny fraction - less than one-tenth of one percent - of all possible drug-like molecules. So the question is: what happens when AI suddenly opens up the other 99.9%? Dr. Olga Nissan, Ph. D. is Vice President of Business Development at Evogene ( https://evogene.com/ ) where she leads pharmaceutical partnerships for the company’s ChemPass AI generative che...

Send us Fan Mail For decades, medicine focused on helping us live longer. Then came healthspan - helping us stay healthier longer. But what if the next frontier is something even deeper: joyspan… the quality, meaning, and fulfillment of the years we actually live? Today’s conversation sits at the intersection of healthcare delivery, aging science, and one of the most important - and perhaps least...

Send us Fan Mail What if saving a life isn’t a single moment…but the beginning of thousands of future moments that only exist because someone chose to act? Today’s guests are father-daughter duo Brad Newbury ( https://bradnewbury.com/ ) and Kiera Newbury ( https://kieranewbury.com/ ) - two voices at the intersection of emergency medicine, leadership, resilience, and human impact. Brad is a veteran...

Send us Fan Mail We used to think of DNA as something we read. Now we’re starting to treat it like something we write - and that changes everything about how medicine gets made. Dr. Patrick Finn, Ph. D. is President and COO of Twist Bioscience ( https://www.twistbioscience.com/ ), a company that’s helping turn biology into something you can engineer, iterate, and even industrialize.  Dr. Finn has...

Send us Fan Mail For more than 30 years, small cell lung cancer has remained one of the most aggressive and difficult-to-treat cancers - marked by rapid progression, high relapse rates, and very few meaningful advances. But that may finally be starting to change. Today, we’re joined by Dr. Angela Coxon, Ph. D., Vice President of Research and Development at Amgen ( https://www.amgen.com/ ), where s...

Send us Fan Mail What if the future of medicine isn’t about treating disease…but detecting it 20 years before symptoms ever appear? Dr. Julie Chen, MD is helping lead one of the newest precision-health companies trying to build that future. Dr. Julie Chen, MD is a physician operating at one of the most interesting intersections in modern medicine: rigorous clinical research, precision longevity me...

Send us Fan Mail Psychedelic medicine is no longer fringe science - it’s now part of White House policy discussions, FDA fast-track programs, and a rapidly emerging neuropsychiatric industry. But can these therapies truly become scalable standards of care? Eric So is Co-Founder and Executive Chairman of Helus Pharma ( https://www.helus.com/ ), a company focused on developing next-generation seroto...

Send us Fan Mail What if the next breakthrough cancer therapy can’t be manufactured on Earth at all? In this episode, BioOrbit CEO Dr. Katie King explains how microgravity may unlock entirely new classes of medicines - from ultra-precise biologics to cancer therapies manufactured in orbit aboard future pharmaceutical factories in space. Dr. Katie King, Ph. D is a scientist, entrepreneur, and space...

Send us Fan Mail What if the biggest public health threat to attention, sleep, relationships, and mental health isn’t a virus or a disease - but the device in your pocket? Dr. Nidhi Gupta, MD ( https://reconnect.expert/Dr-Nidhi-Gupta ) is a pediatric endocrinologist, TEDx speaker, researcher, entrepreneur, and one of the leading voices exploring the intersection of technology, health, and human co...

Send us Fan Mail Every year, thousands of newborns suffer devastating brain injury during birth - and despite decades of research, there are still no approved drug therapies for Hypoxic Ischemic Encephalopathy (HIE). But one biotech company believes it may finally have a solution. Dr. Howard Berman, Ph. D. is Chief Executive Officer and Chairman of ReAlta Life Sciences ( https://realtalifesciences...

Send us Fan Mail What if you could ship a nuclear power plant like a container - and run it for years without refueling? Josef Freundorfer is the CEO of Nuclea Energy ( https://www.nuclea.energy/ ), where he is leading the development of next-generation nuclear microreactors designed to bring reliable, zero-carbon power to some of the world’s most challenging environments. An engineer by training,...

Send us Fan Mail There’s a hidden supply chain crisis happening in fine dining right now - and it’s something as simple, and as essential, as chocolate. Brandon Olsen is a world-class chef and chocolatier known for blending high-end culinary artistry with bold, modern creativity. He trained at some of the most prestigious kitchens in the world, including The French Laundry under Thomas Keller, bef...

Send us Fan Mail On any given night, more than 750,000 people are homeless in America - but that number doesn’t even begin to tell the full story. Today’s conversation sits at the intersection of advocacy, lived experience, and storytelling - because ending homelessness isn’t just a policy challenge, it’s a human one. Our first guest, Donald Whitehead Jr., is one of the leading voices in the fight...

Send us Fan Mail We may be building something entirely new - a kind of digital nervous system for the planet, where satellites and AI are constantly sensing and interpreting what’s happening on Earth. Sean Donegan is the Founder and CEO of Satelytics ( https://www.satelytics.com/ ), a pioneer in applying artificial intelligence to high-resolution satellite imagery to monitor and protect critical i...

Send us Fan Mail Doctors in North America are now prescribing something you can’t buy at a pharmacy… and it’s backed by a growing body of science.  Jennie McCaffrey is the Vice President of Health & Education at the BC Parks Foundation ( https://bcparksfoundation.ca/ ), where she leads initiatives designed to connect people to nearby nature for the benefit of both human health and the planet....

Send us Fan Mail Imagine a device that can sense disease in real time… and treat it instantly. That’s the promise of Bioelectronics. Dr. Robert Spoelgen, Ph. D. is Vice President and Head of Bioelectronics at Merck KGaA Darmstadt Germany ( https://www.emdgroup.com/en/the-future-transformation/healing-power-electronics.html ), where he leads one of the company’s most forward-looking initiatives at...

Send us Fan Mail Today’s conversation sits at the intersection of one of the most ambitious - and most challenging - frontiers in modern medicine: regenerative cell therapy. For decades, the vision has been incredibly compelling - replace damaged or dying cells with healthy ones, and you could potentially restore function in diseases like macular degeneration, spinal cord injury, hearing loss, and...

Send us Fan Mail In times of crisis, innovation doesn’t slow down - it accelerates. Over the past several years, Ukraine has become globally recognized for its rapid advances in defense technology - particularly in drones and distributed manufacturing. But alongside that transformation, another revolution has been quietly taking shape: the future of medicine, built under extreme conditions. Today,...

Send us Fan Mail Today on Progress, Potential And Possibilities, we explore a different kind of breakthrough in cognitive health - not a drug, not a device, but a simple daily practice that’s quietly transforming lives. Our guest is Rob Liebreich, President and CEO of Goodwin Living ( https://goodwinliving.org/ ), an organization serving thousands of older adults across the Washington, D.C. region...

Send us Fan Mail Today’s conversation is part of a new series we’re launching — ‘Past Forward: Lessons for the Next Century.’  In this series, we examine pivotal moments, systems, and individuals from the past - not to relive them, but to better understand how they continue to shape the world we are building.  Because many of the defining forces of our time - globalized networks, technological esc...

Send us Fan Mail What if a simple blood test could detect Alzheimer’s years—maybe even decades—before symptoms ever appear? Mike Banville is the Chief Executive Officer of ALZpath ( https://alzpath.bio/ ), a company at the forefront of transforming how Alzheimer’s disease is detected and monitored through cutting-edge blood-based diagnostics. Mike is a seasoned global executive with a track record...

Send us Fan Mail There’s a revolution happening in pet health right now - where a simple stool sample can reveal disease risk, immune health, and even how long your dog might live. Dr. Bushra Schuitemaker, Ph. D. is a microbiologist, zoologist, and science leader working at the cutting edge of microbiome research, animal health, and nutrition.  Dr. Schuitemaker serves as Head of Science and Resear...