Progress, Potential, and Possibilities Podcast / Show

Send us Fan Mail For decades, scientists have searched for better cancer drugs. But what if the biggest challenge isn't discovering the drug - it's getting it to the tumor? My guest today is developing programmable viruses designed to travel throughout the body, selectively amplify inside metastatic lesions, and transform tumors into factories for their own destruction. Dr. Eric Poma, Ph...

Send us Fan Mail For decades, oncologists have had to wait until cancer became visible on a scan before knowing whether it had returned. But what if doctors could detect microscopic traces of cancer months earlier with a simple blood draw - and use that information to decide who actually needs treatment? Today we're exploring a breakthrough that may fundamentally change the way cancer is moni...

Send us Fan Mail For decades, medicine has recognized that pregnancy and menopause transform nearly every system in the body. Yet only recently have researchers begun asking a simple question: what happens to chronic skin diseases like eczema and psoriasis during these major biological transitions? The answers may reveal one of the biggest blind spots in modern medicine. Dr. Doral Fredericks, Phar...

Send us Fan Mail He spent fifty-five years searching for answers. Dozens of doctors. Hundreds of tests. Twelve different diagnoses. And what he discovered wasn't just a problem with medicine - it was a problem with the system itself. Haresh Patel ( https://hareshpatel.ai/ ) is an entrepreneur, engineer, Founder and CEO of Sanare Health AI ( https://sanarehealth.ai/ ), and author of the memoir...

Send us Fan Mail Before your heart, brain, or lungs fully developed, one remarkable temporary organ was making decisions that may influence your health for decades. Dr. Perrie O'Tierney-Ginn ( https://www.placentascience.com/ ) explains why the placenta could be the most important organ you've never thought about. Dr. Perrie O'Tierney-Ginn, Ph. D. is Executive Director of the Woman,...

Send us Fan Mail Dogs can detect explosives, narcotics, missing persons, and even disease. But what if their greatest superpower isn't finding things - it's sensing molecular changes inside the human body long before symptoms appear? Today we're exploring whether the canine nose may hold the key to the next generation of cancer diagnostics. Itamar Bitan is the Co-Founder of Dognosis...

Send us Fan Mail What if aging isn’t just biology…but also psychology - and your brain is quietly shaping how fast you age every day? Dr. Srini Pillay, MD ( https://drsrinipillay.com/ ) is a Harvard-trained psychiatrist, brain researcher, entrepreneur, author, and expert in the science of human potential, resilience, and longevity. Dr. Pillay previously served as Assistant Professor of Psychiatry...

Send us Fan Mail For decades, we’ve talked about the digital revolution - but according to Professor Klaus Schwab, we’ve already moved beyond it. We’re now entering what he calls the Intelligent Age - where intelligence itself becomes the most valuable resource on Earth. Professor Klaus Schwab is Founder of the World Economic Forum and one of the most influential thinkers on how technological and...

Send us Fan Mail He spent decades interviewing some of the toughest athletes on the planet. Meanwhile, he was quietly battling a condition that at times covered nearly his entire body. Today, for the first time, Paul shares the story behind the story. Paul is an 11-time Emmy Award-winning sports television producer whose career has taken him behind the scenes of some of the biggest moments in spor...

Send us Fan Mail We spend enormous amounts of time trying to extend life - but almost no time learning how to deal with the fact that it ends. And that gap is creating enormous suffering for families. Dr. Marianne Matzo, Ph. D., FAAN is a nationally recognized gerontologist, hospice nurse, educator, researcher, and advocate whose career has been devoted to one of the most universal - and often avo...

Send us Fan Mail What if we could recreate the inside of a star - not in theory, but inside a laboratory on Earth using the world’s most powerful lasers? Dr. Mario Manuel, Ph. D. is a plasma physicist and laser-science researcher at whose work sits at the frontier of fusion energy, laboratory astrophysics, high-energy-density physics, and advanced laser diagnostics. Trained in applied plasma physi...

Send us Fan Mail Over the last several years, artificial intelligence has transformed from a speculative concept in healthcare into one of the most heavily funded movements in pharmaceutical and biotech history. But in 2026, the conversation is changing. The question is no longer whether AI can generate molecules, analyze pathology slides, or identify patterns in clinical data. The real question i...

Send us Fan Mail What if modern medicine has become incredibly good at saving children’s lives…but society still hasn’t figured out how to help many of those children truly live afterward? Dr. Nicholas Holekamp, MD is the Chief Health Transformation Officer at Ranken Jordan Pediatric Bridge Hospital in St. Louis ( https://rankenjordan.org/about-us/leadership/nicholas-holekamp-md/ ), one of only a...

Send us Fan Mail For decades, agriculture and energy were treated as separate worlds. But what happens when farms become part of the global energy infrastructure? Ofer Haviv joins us to discuss the rise of castor as a next-generation industrial crop, the future of sustainable aviation fuel, and how AI-driven biology is transforming agriculture itself. Ofer Haviv is CEO of Casterra ( https://caster...

Send us Fan Mail Every once in a while, a simple question changes medicine forever. For decades, chronic and traumatic wounds were among the most frustrating problems in healthcare. Doctors could clean wounds, dress wounds, and hope for healing - but many patients remained trapped in cycles of infection, inflammation, and failed recovery. Then came one deceptively simple idea:  What happens if you...

Send us Fan Mail For years, T cell therapies have transformed blood cancers - but solid tumors have remained one of the hardest problems in medicine. Now a new company called Deck Bio believes the issue isn’t just finding a better target...it’s that cancer may never have been a single-target disease in the first place. Dr. Jack Silberstein, Ph. D. is the Founder and CEO of Deck Bio ( https://deck....

Send us Fan Mail Most people assume national security delays are about technology. They’re not.  They’re about paperwork - and it can take up to two years just to deploy software the government already wants. Andrew Black is a national security entrepreneur, cybersecurity executive, and emerging technology strategist whose career has sat at the intersection of AI, defense, cyber risk, and global s...

Send us Fan Mail What if the next pandemic could be identified, diagnosed, and targeted with programmable CRISPR therapeutics before it spreads globally? That’s exactly what Seek Labs is trying to build. Jared Bauer is CEO of Seek Labs ( https://seeklabs.com/ ), a clinical-stage TechBio company developing an integrated platform that combines AI-driven genomic intelligence, rapid field diagnostics,...

Send us Fan Mail Every product you buy has a journey - but for most companies, that journey is basically invisible until something goes wrong. Today we are diving into one of the most overlooked - yet absolutely essential - pieces of global commerce: the pallet. Every year, billions of products move across the world sitting on these simple platforms, but despite the rise of AI, IoT, robotics, and...

Send us Fan Mail What if medicines could actually “decide” when and where to activate inside the body? MIT-trained synthetic biologist Dr. Jacob Becraft, Ph. D. is building programmable therapies that behave less like traditional drugs…and more like biological software. Dr. Becraft is Co-Founder and CEO of Strand Therapeutics ( https://www.strandtx.com/ ), a company pioneering what may become one...

Send us Fan Mail Bladder cancer treatment is entering a new era. From gene therapy and bladder preservation to AI-assisted diagnostics and the challenge of detecting “hidden” CIS, Dr. Ravi Chauhan, MD, FACS breaks down the technologies and clinical decisions reshaping urology in 2026. Dr. Ravi Chauhan, MD, FACS ( https://conradpearson.com/our-specialists/ravi-d-chauhan-m-d-facs/ ) is a board-certi...

Send us Fan Mail What if the biggest problem in nuclear energy isn’t reactor technology…but paperwork, regulation, and institutional bottlenecks? Today we explore how AI could compress nuclear deployment timelines from decades to years. Kevin Kong is founder and CEO of Everstar ( https://everstar.ai/ ), a company building advanced AI reasoning systems designed to accelerate the deployment of nucle...

Send us Fan Mail Drowning is the leading cause of death for children ages 1 to 4 in multiple countries - yet it receives only a fraction of the attention of other public health crises. Why? Acacia Landfield is Associate Director, Principal Investigator, and Director of Policy & Implementation Science at The Drowning Research & Injury Prevention Policy Institute ( DRIPPI - https://www.dripp...

Send us Fan Mail For decades, the beauty industry focused on creams, serums, and surface-level solutions. But what if aging skin is really a reflection of something much deeper happening inside our cells?  Today’s guest is François Vix, a longtime global beauty and wellness executive who has spent more than four decades at the intersection of skincare science, redox biology and oxidative stress re...

Send us Fan Mail Some of the most important cancer and autoimmune disease drugs in the world still require patients to sit in infusion chairs for hours - but that model may be about to change entirely. Matthew Huddleston is Chief Commercial Officer at Enable Injections ( https://enableinjections.com/ ), a medical device company focused on rethinking how large-volume biologic drugs are delivered to...