Peptides With Michele

You put in the work. You hit your goal on a GLP-1. Now what. This episode picks up where episode 22 left off and answers the question I get asked a lot. If you have not listened to episode 22 — GLP-1s. What You Need to Know While You Are On One. I recommend starting there first. Today I am talking about what actually happens after you hit your goal. And I am not going to sugarcoat it. The research...

I have done a lot of episodes on individual peptides. And I have talked before about why your body stops responding after 40. But I have never connected all of those dots in one place. Until now. In this episode I walk you through exactly what the research shows is happening in your body after 40, the specific biological changes that are documented and real, and for each one I tell you which pepti...

In this episode I break down Dihexa, one of the most talked about compounds in the brain health and longevity space right now. I start by addressing something I know longtime listeners are going to wonder immediately. I talk a lot on this podcast about how most peptides do not work when taken orally. So why does Dihexa come as a capsule. I explain exactly why in plain language and why this is comp...

In this episode I break down Epitalon, one of the most fascinating peptides in the longevity space. It was also reviewed by the FDA advisory committee on July 24th 2026, the second day of the same historic hearing I covered in my recent episode. Epitalon is a tiny four amino acid peptide derived from the pineal gland that has been studied for over 40 years for its role in activating telomerase, th...

In this episode I cover Tesamorelin, one of the most research backed peptides I have ever talked about on this podcast. Unlike most compounds in this space Tesamorelin has full FDA approval and two large Phase 3 human clinical trials behind it showing real measurable reductions in visceral fat, the deep internal fat around your organs that is the most dangerous kind and the hardest to lose. I expl...

This is part two of a conversation I started in my last episode. Before You Inject Anything. What You Need to Know About Research Grade Peptides and Why It Matters. If you have not listened to that one yet I recommend starting there first. In this episode I want to talk about something I get asked about constantly. People are going to wellness clinics and med spas and getting peptide injections. A...

I have been getting messages from people who are mixing and injecting peptides on their own with no doctor involved, no guidance on how to reconstitute them correctly, and no idea what dose is appropriate for their situation. This episode is for them. And for anyone who is considering going that route. I am not here to judge anyone. I am here to give you the information you may have not been given...

Getting on a GLP-1 is just the beginning. What you do while you are on it matters enormously for your results and your long term health. In this episode I cover the five most important things for anyone who is on or considering a GLP-1. I’m discussing protein and why it is the most critical thing to prioritize and what the published research actually says about how much you need to protect your mu...

This is one of the most personal episodes I have done. I have Lyme disease. I was diagnosed in my late 40s completely by accident through a routine eye exam with a new doctor who noticed something previous exams had missed. Specialists. A CT scan. Comprehensive blood tests. And buried in those results was Lyme disease, something nobody had even been looking for. The eye and the Lyme turned out to...

In this episode I break down Semax, a peptide that has been used clinically in Russia for decades and is now being talked about seriously in the longevity and cognitive health space. And yes it is a nasal spray. I explain exactly why in plain language and the science behind it is genuinely fascinating. The nose to brain delivery pathway is real and it is the reason this specific compound works the...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down PT-141 and why it is one of the most legitimately researched peptides I have ever covered on this podcast. It has full FDA approval under the brand name Vyleesi, the first non-hormonal treatment ev...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. Today something happened that I have never seen before in this space. I watched live as a formal FDA advisory committee voted in favor of four of the most researched peptides in the wellness and longevity world for inclusion o...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. This podcast has always been about education. But the question I get asked more than almost anything else is where do I actually get my peptides and who do I trust. So today I am finally doing a full episode on it. I walk thro...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down Methylene Blue, a pharmaceutical grade compound that has been used in medicine since the 1890s and is now one of the most interesting things being studied in the longevity and brain health space. Y...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down something every single woman in midlife has experienced. Why your body just stops responding the way it used to. You are doing everything right and nothing is working the way it did in your thirtie...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I go deeper on GLP-1s, specifically the conversation everyone is having right now about microdosing tirzepatide and semaglutide. Not for dramatic weight loss. For metabolic health, inflammation, cardiovascular...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down sermorelin, the peptide that does not do the job itself, it tells your body to do the job. Specifically it signals your pituitary gland to release its own growth hormone the natural way. Growth hor...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down KLOW, a four peptide blend combining BPC-157, TB-500, GHK-Cu, and KPV into one single formula. If you have heard my episodes on GHK-Cu and BPC-157 plus TB-500 and wondered what it would look like t...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down Melanotan II, a man-made peptide designed to copy a signal your body already knows how to receive, that activates a whole network of switches throughout your body and your brain. I’m explaining it...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down glutathione, the tiny peptide researchers call the “master antioxidant” that your body has been making on its own your entire life. Today I’m covering what it actually is, why levels drop as we get...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down DSIP, also known as Delta Sleep Inducing Peptide, the tiny peptide everyone is asking me about for sleep. Today I’m covering what it actually is, why people are so curious about it, and what the re...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down NAD+, the tiny helper molecule inside every single one of your cells that makes energy possible, and the one your body loses nearly half of by the time you’re 50. Plot twist: NAD+ is not technicall...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down BPC-157 and TB-500. The two peptides that people talk about together so often they’ve earned the nickname “the recovery power couple.” Explained like you’re in 5th grade. We get into what each pept...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down GHK-Cu, the tiny three-amino-acid peptide everyone is talking about. Mine was just delivered, so today I’m covering what it actually is, why people are so obsessed, and what the research says, expl...

This podcast is for educational purposes only and is not intended as medical advice. I am not a doctor. Always consult your physician before starting any new health regimen. In this episode I break down Thymosin Alpha-1, one of the most studied peptides in existence and the one I personally swear by. I share my own experience after almost four months on it, including a breathing test result that s...