NSF’s Discovery Files Podcast

From atoms and molecules to cells, understanding the building blocks of the natural world can lead to transformative technologies. NSF-supported researcher Torrey Rhyne-Carrigg discusses DNA initiators, using models for analysis, and her experience in the Graduate Research Fellowship Program.

Coordinated action across disciplines can deliver transformative technologies. U.S. National Science Foundation-supported researcher Rajesh Menon discusses his work combining optical systems with cutting-edge nanofabrication.

Scientific discovery can unlock innovations that develop into technologies with extraordinary properties. NSF-supported researcher Morteza Kayyalha discusses his work developing quantum-enabled materials and devices.

Solutions-oriented research is improving the lives of American people. NSF-supported researcher Jeremy Brown discusses his work developing interfaces with haptic feedback, including upper-limb prosthetics, rehabilitation tools, and surgical robotics.

Advanced technologies are transforming industry, society, and people's daily lives. Shelly Zhang, an NSF-supported researcher, discusses her work using additive manufacturing and topology optimization to create new structures, including a 3D thermal cloaking device.

Cutting-edge science and technology advancements are revolutionizing artificial intelligence systems. Mark Hersam an NSF-supported researcher, discusses nanoelectronic materials and how acerebellum-inspired approach may transform how AI performs in wearable devices.

Advances in materials science have delivered everything from nylon stockings to artificial joints. Chunlei Guo, an NSF-supported researcher, discusses his work using femtosecond lasers to design materials with highly functionalized purposes.

U.S. National Science Foundation-supported researchers are behind an educational effort to introduce artificial intelligence techniques to elementary school children. Educator Carrie Robledo discusses her project, "AI Insect Detectives," and experience as a 2026 Presidential AI Challenge national champion.

Tiffany Barnes, Shiyan Jiang and Xiaoyi Tian discuss their U.S. National Science Foundation-supported project "ElementaryAI," the challenges of introducing artificial intelligence concepts into elementary school curriculum and how the project led to a win in the inaugural Presidential AI Challenge.

NSF Noirlab's Robert Blum, director of operations for the NSF-DOE Vera C. Rubin Observatory, discusses the observatory's signature mission, the Legacy Survey of Space and Time, and how it will transform the way we study the universe.

As the 10-year Legacy Survey of Space and Time officially starts and the greatest cosmic movie ever made is captured, U.S. National Science Foundation Program Officer Edward Ajhar discusses the NSF-DOE Vera C. Rubin Observatory and how it will transform the way people study the universe.

An innovative new engineering approach may lead to denser, more powerful microchips and computing systems. U.S. National Science Foundation-supported researcher Qing Cao discusses a new monolithic, 3D-integrated silicon microchip and how it might impact artificial intelligence systems.

New, lifesaving treatments can be found at the intersection of bioengineering and medicine. U.S. National Science Foundation-supported professor Neil Forbes discusses how the bacteria salmonella can be modified for treatment against some of the deadliest cancers.

U.S. National Science Foundation-supported professor and director of the NSF Center for Complex Particle Systems Nicholas Kotov discusses complex materials and the development of new fused silk materials with applications in security and communications.

Hypertension affects nearly half of U.S. adults, and 10% of those cases don’t respond well to treatment. U.S. National Science Foundation-supported professor Tao Zhou discusses the development of a new 3D-printed hydrogel-based bioelectronic device for hypertension treatment.

Secure information is essential in the digital exchanges of modern life. U.S. National Science Foundation-supported professor Vinod Vaikuntanathan discusses quantum cryptography and the future of encryption.

Advancements in science and technology impact the well-being of the American people. U.S. National Science Foundation-supported professor Payam Heydari discusses a breakthrough brain-computer interface that controls a robotic exoskeleton, technology that could transform the lives of people living with spinal cord injuries.

Nearly 3 million antimicrobial-resistant infections occur every year in the United States. U.S. National Science Foundation-supported professor Kevin Minbiole discusses his work using artificial intelligence systems to discover new compounds to fight drug resistant bacteria.

Science, technology, engineering and mathematics-related fields employ 25% of the U.S. workforce. U.S. National Science Foundation-supported professors Erica Carlson and Muhsin Menekse discuss how their collaboration is inspiring the next generation of STEM workforce through a quantum education program.

Advances in artificial intelligence-driven technologies have the potential to impact the lives of Americans living with hearing loss substantially. Yasmin Kassim, a postdoctoral fellow and member of a group supported in part by NSF, has developed a deep learning-based tool that allows unparalleled insights into the hair cells that allow us to hear.

Emerging artificial intelligence technologies are transforming the American enterprise. Madhur Behl, an NSF-supported associate professor, discusses software challenges in autonomous racing and how his program is helping to develop the AI workforce of the future.

Artificial intelligence techniques are driving the development of autonomous vehicles. Madhur Behl, an NSF-supported associate professor, discusses how the high-speed world of racing helps advance safe autonomous vehicles.

In the health care industry, artificial intelligence, machine learning and advanced robotic systems could help solve many of the issues facing the field today. Axel Krieger, an NSF-supported associate professor, discusses his work developing autonomous surgical robots.

Artificial intelligence advancements in machine learning are allowing autonomous exploration in remote underwater environments. Katie Skinner, an NSF-supported assistant professor, discusses work advancing the field of robotics by combining computer vision with AI advancements in machine learning.

The future of quantum information science and engineering promises computers with unprecedented speed and capabilities. Miloš Popović, an NSF-supported associate professor, discusses a collaboration that has built a photonic quantum system into a traditional electronic chip.