In Vivo

In this wide-ranging conversation, Dr. Michael Shermer, founder of Skeptic Magazine and the Skeptics Society, opens up about his personal journey from born-again Christian to one of the world’s most respected scientific skeptics. He shares how his faith unraveled during his graduate studies, the role James Randi and Uri Geller played in shaping modern skepticism, and why critical thinking has beco...

Why do humans sleep less than any other primate on Earth, yet possess the largest brains and highest cognitive abilities? In this episode of In Vivo, evolutionary biologist Dr. David Sampson joins the show to unpack the fascinating paradox of human sleep. We dive deep into his immersive fieldwork with the Hadza tribe, the neural mechanics of how your brain flushes out toxins at night, and why our...

Dr. Mithu Storoni, author of the 2025 Business Book of the Year Hyperefficient, reveals a complete neuroscience-based system to dramatically improve focus, creativity, and productivity in the age of AI.In this conversation we explore:• Why the old “assembly-line” model of work is broken for knowledge work and students• The 3 Brain Gears that control your mental performance (and how to switch betwe...

Physicist Dr. Melvin Vopson (University of Portsmouth) joins In Vivo to explain his groundbreaking Second Law of Infodynamics — the idea that information in the universe constantly compresses and minimizes itself, the exact opposite of the Second Law of Thermodynamics. In this episode he shows how this law can derive Newton’s law of gravity as an emergent computational optimization process, why vi...

In this episode, Eric Jorgenson, author of the bestselling The Almanack of Naval Ravikant and The Book of Elon, breaks down Elon Musk’s most useful ideas for students, young professionals, and anyone who wants to think and operate at a higher level. We explore:• How to apply First Principles Thinking to school, career, and life• Why you should play life like a game and optimize for what actually m...

What is energy in biology? In this eye-opening conversation, biophysicist Dr. Nirosha Murugan reveals that life is not just chemistry or genes, it is structured, patterned energy in constant flow. She explains why the dynamic flow of energy is what separates a living cell from a dead one, how cells emit ultra-weak light called biophotons, and why diseased cells (including cancer) have completely d...

In this deep-dive conversation, evolutionary biologist Dr. Bret Weinstein joins me to explore his groundbreaking hypothesis: that Variable Number Tandem Repeats (VNTRs) function as genomic “sliders”, numerical variables stored in non-coding DNA that allow evolution to rapidly explore adjacent forms and solve major gaps in neo-Darwinism. We discuss why evolutionary theory has stalled for decades, h...

Do we actually have free will, or is it just a neurobiological illusion? In this fascinating episode, neuroscientist and bioengineer Dr. Nic Rouleau explains why our feeling of making choices might just be a hardwired neurological superstition. We dive deep into the world of cybernetics, exploring why living biological computers are currently vastly more efficient at learning than modern artificia...

In this episode of In Vivo Podcast, Dr. Antonei Csoka, biogerontologist and Director of the Epigenetics Laboratory at Howard University College of Medicine, shows how studying Hutchinson-Gilford Progeria Syndrome, the most extreme accelerated aging disease, is giving us the keys to achieving radical longevity and possibly biological immortality. As one of the scientists who discovered the LMNA gen...

What if your brain is actually a "reducing valve" that filters out most of reality? In this episode, we dive deep into the world of DMT (N-Dimethyltryptamine) and 5-MeO-DMT with Dr. Chris Timmermann from the Center for Psychedelic Research at Imperial College London. His work focuses on the effects of DMT on the human brain and how it can help us understand the relationship between brain...

Dr. Aiello is a quantum engineer and researcher working at the intersection of quantum physics, quantum engineering, and quantum biology, to explore a provocative idea: that there may be a basal, underlying quantum layer to life itself. Many people encounter quantum mechanics for the first time and come away thinking it’s mysterious, abstract, or even “magic.” But as Dr. Aiello explains, quantum m...

In this episode of In Vivo, we dive deep into the "Hard Problem of Consciousness" with world-renowned anesthesiologist and researcher Dr. Stuart Hameroff. For decades, the mainstream scientific community has viewed the brain as a biological computer, with consciousness being a mere byproduct of complex neural wiring. But Dr. Hameroff, alongside Nobel Laureate Sir Roger Penrose, suggests...

In this episode, I sit down with Dr. Robert Malone, the scientist credited with the invention of mRNA transfection technology, to discuss the true history of one of the most important tools in molecular biology. We go beyond the mainstream headlines to explore the moment of discovery at the Salk Institute, the "stolen valor" of the 2023 Nobel Prize, and the ethical crossroads facing mode...

My guest today, Dr. Oded Rechavi, is a brilliant polymath who has dedicated his career to radical problem-solving. He's famous for discovering the inheritance of acquired memories and using ancient DNA sequencing to reconstruct the 2,000-year-old Dead Sea Scrolls. But now, he's tackling his biggest problem yet: the broken peer review process. The system, which has been the "gold stand...

Former FDA medical officer Dr. Josef Witt-Doerring joins me to blow the whistle on the widespread overprescription of psychiatric medications and the dangerous lack of proper SSRI tapering guidance. Dr. Witt-Doerring, who served in the FDA's Division of Psychiatry, reveals how the entire system—from clinical trials to prescribing habits—is built on a flawed foundation. He exposes the truth beh...

In this episode I speak with Dr. Emma Hapke, a leading psychiatrist, psychotherapist, and psychedelic researcher who ran the MAPS Canada MDMA trials in Montreal. Dr. Hapke provides an expert, on-the-ground look at the clinical trials and therapeutic process using substances like MDMA for PTSD and high-dose Psilocybin therapy for patients struggling with depression and end-of-life distress (fear of...

Dr. Shawn Baker joins me to discuss the Carnivore Diet, his status as a controversial figure, and why he believes current nutrition science is failing the public. As a pioneering orthopedic surgeon and world-record-holding athlete, Dr. Baker provides an unfiltered look at the benefits of an all-meat diet for achieving peak athletic performance in his 50s. We deep-dive into the corporate interests...

In this episode of In Vivo, I sit down with Dr. Nicholas Fabiano, a psychiatry resident and leading voice challenging the very foundation of modern mental health care. Dr. Fabiano argues that by separating the mind and body, Western medicine has created a dangerous medical divide that is failing patients. We dive deep into his viral assertion: "Could not prescribing exercise for depression be...

On September 22, 2025, the Trump administration held a landmark press conference in the White House Roosevelt Room, presenting evidence linking prenatal acetaminophen (Tylenol) exposure to autism spectrum disorder (ASD). Led by President Trump and HHS Secretary Robert F. Kennedy Jr., the announcement prompted immediate FDA actions, including label reviews and advisories urging caution during pregn...

In this episode of In Vivo, we sit down with Dr. Tomás Duraj to challenge a century of conventional wisdom about cancer. For decades, the dominant theory has been the somatic mutation theory, which suggests cancer is a genetic disease caused by random mutations. Dr. Duraj and his colleagues are proposing a paradigm shift, viewing cancer as a mitochondrial metabolic disease. This theory explains th...

Dive into the science of sleep with Dr. Michael Mak, a leading psychiatrist and sleep medicine specialist at CAMH (Centre for Addiction and Mental Health) in Toronto. In this episode, we explore why sleep is essential for peak performance, memory consolidation, and mental health. Dr. Mak breaks down sleep stages (deep sleep, REM), the glymphatic system's role in brain detox and dementia prevention...

I spoke with Dr. Brandon Luu, an Internal medicine–trained Medical Doctor currently specializing in Respirology, as he breaks down the science behind creatine, nicotine, and binaural beats. Discover why these three are buzzing in fitness, cognitive enhancement, and sleep deprivation circles. From boosting muscle strength to enhancing focus during, Dr. Luu shares evidence-based insights and persona...

Dive into the science of flow states with Dr. David S. Rosen, a cognitive neuroscientist at Johns Hopkins’ Center for Psychedelic and Consciousness Research. Discover how to enter flow state through his groundbreaking research on jazz improvisation, revealing the neuroscience behind creativity and peak performance. Dr. Rosen, an accomplished musician and member of the band Outer States, shares ins...

In this episode, I speak with Dr. Matthew Szydagis, an experimental physicist at the University of Albany, as he dives into the mysteries of dark matter, time travel, and unidentified anomalous phenomena (UAPs). Discover how the Lux Zeplin experiment hunts for dark matter, the invisible "glue" holding the universe together, and explore groundbreaking ideas about time travel, including a...

Asteroids like Bennu might hold the secrets to life’s origins on Earth and beyond. Now, thanks to a daring NASA mission, we’ve got a pristine sample that could rewrite our cosmic story. In this episode of In Vivo, I sit down with Dr. Scott Sandford, a NASA astrophysicist and OSIRIS-REx team member, to discuss:• How Bennu’s amino acids and nucleobases hint at a universe primed for life• Why OSIRIS-...