ENT Update

頭頸外科與腫瘤學專題：補救手術與復發性頭頸癌(RESCUE,PMID:42208312,https://pubmed.ncbi.nlm.nih.gov/42208312/) | 靜脈吻合一條vs兩條統合分析(PMID:42203589,https://pubmed.ncbi.nlm.nih.gov/42203589/) | 虛擬手術計畫下頜骨ORN重建(PMID:42206699,https://pubmed.ncbi.nlm.nih.gov/42206699/) | 再次放療併用pemetrexed/erlotinib復發頭頸癌(PMID:42116977,https://pubmed.ncbi.nlm.nih.gov/42116977/)

本週回顧專題：頭頸腫瘤新藥(TORPEdO,PMID:42183251,https://pubmed.ncbi.nlm.nih.gov/42183251/) | 食道癌FLOT新輔助化療(PMID:42213868,https://pubmed.ncbi.nlm.nih.gov/42213868/) | fNIRS聽損皮質評估(PMID:42192844,https://pubmed.ncbi.nlm.nih.gov/42192844/) | 兒童早期聽覺刺激(PMID:42194183,https://pubmed.ncbi.nlm.nih.gov/42194183/) | CRSwNP Radiomics評分(PMID:42188339,https://pubmed.ncbi.nlm.nih.gov/421883...

AI在ENT專題：AI口腔癌診斷(Ben Dor,PMID:42207210,https://pubmed.ncbi.nlm.nih.gov/42207210/) | AI喉鏡診斷scoping review(PMID:42153409,https://pubmed.ncbi.nlm.nih.gov/42153409/) | Gemini評估聲帶注射技術(PMID:42185941,https://pubmed.ncbi.nlm.nih.gov/42185941/) | AI助聽器病人認知討論(PMID:42190300,https://pubmed.ncbi.nlm.nih.gov/42190300/)

喉科學專題：前路頸椎術後吞嚥與聲音評估(SR入路,PMID:42200633,https://pubmed.ncbi.nlm.nih.gov/42200633/) | 左側聲帶麻痺竟是主動脈瘤表現！(黴菌性動脈瘤,PMID:42206081,https://pubmed.ncbi.nlm.nih.gov/42206081/) | 咳嗽病理生理學綜述(神經免疫失調,PMID:42203561,https://pubmed.ncbi.nlm.nih.gov/42203561/)

維生素D與頭頸癌特輯：UNESCO乳癌RCT維生素D化療(PMID:40098326,https://pubmed.ncbi.nlm.nih.gov/40098326/) | 維生素D增進cisplatin敏感性LCN2/NF-κB(PMID:31819048,https://pubmed.ncbi.nlm.nih.gov/31819048/) | VDR-BIM克服cisplatin抗藥HNSCC(PMID:36291915,https://pubmed.ncbi.nlm.nih.gov/36291915/) | 維生素D缺乏HNSCC預後免疫(PMID:30228945,https://pubmed.ncbi.nlm.nih.gov/30228945/) | 術前25(OH)D與喉切除術後併...

睡眠醫學專題：OSA-CV綜論(PMID:42200975,https://pubmed.ncbi.nlm.nih.gov/42200975/) | CPAP預防心血管事件統合分析(PMID:42110829,https://pubmed.ncbi.nlm.nih.gov/42110829/) | CBT-I合併BZD減量(PMID:42168527,https://pubmed.ncbi.nlm.nih.gov/42168527/) | 數位CBT-I降低過度警醒(PMID:42184726,https://pubmed.ncbi.nlm.nih.gov/42184726/) | OSA種族差異系統性回顧(PMID:42196707,https://pubmed.ncbi.nlm.nih.gov/42196...

ENT特輯：2026年5月一週學術精選 | CRSwNP七種生物製劑網絡統合分析(PMID:41999554,https://pubmed.ncbi.nlm.nih.gov/41999554/) | TCRF鼻閥阻塞治療24個月睡眠追蹤(DOI:10.1002/oto2.70250,https://doi.org/10.1002/oto2.70250) | 頭頸癌放療中斷7天預後影響(PMCID:PMC12679426,https://pmc.ncbi.nlm.nih.gov/articles/PMC12679426/) | 頭頸癌輔助治療時效性JAMA Oto(PMCID:PMC13087907,https://pmc.ncbi.nlm.nih.gov/articles/PM...

鼻科學專題：鼻息肉術後復發分層治療(PMID:42179747, DOI:10.62347/KYDI9328) | 單側鼻竇疾病良惡性鑑別演算法(PMID:42184393, DOI:10.24875/CIRU.24000449) | 薑製劑治療過敏性鼻炎統合分析(PMID:42183789, DOI:10.1080/13880209.2026.2667560) | Montelukast+desloratadine過敏性鼻炎網路統合分析(PMID:42182608)

ENT Update Podcast 2026-05-26 (Tuesday). Topics: ISSNHL vestibular assessment, Koos grade 4 VS SRS pseudoprogression, facial palsy QoL in VS patients, Spanish VADL cross-cultural adaptation. Hosts: Dr. Fu (Puck) & Dr. Lin (Kore).

ENT Update Podcast EP53 - Otology and Audiology (2026/05/26) Papers discussed: 1. vHIT and cVEMPs in sudden SNHL - Rodriguez-Izquierdo et al. Acta Otolaryngol 2026 - DOI:10.1080/00016489.2026.2671348 2. Motorized vs manual CI insertion - Hear Res 2026 - DOI:10.1016/j.heares.2026.109653 3. Pseudoprogression in Koos grade 4 VS after SRS - Schouten et al. J Neurooncol 2026 - DOI:10.1007/s11060-026-05...

ENT Update Podcast EP52 - 頭頸外科與腫瘤學（2026/05/25） 本集論文： 1⃣️ Near-infrared fluorescence imaging-guided surgery using cRGD-ZW800 to improve surgical resection margins in oral cancer: a phase I/II feasibility trial PMID: 42173866 https://pubmed.ncbi.nlm.nih.gov/42173866/ DOI: 10.1038/s41467-026-73554-7 關鍵發現：Phase I/II trial (n=24) 顯示 cRGD-ZW800 螢光導引可即時改變口腔癌手術邊緣決策...

Episode 51-Special | 2026/05/25 — 頭頸部腫瘤最新研究特輯 主持人：傅醫師（Puck）& 林醫師（Kore） 本集論文： 1. 單細胞 HNSCC 惡性細胞異質性與 MCScore 預測工具 (IUBMB Life) DOI: https://pubmed.ncbi.nlm.nih.gov/42068156/ 2. STING 表現預測 LA HNSCC 治療失敗型態 (JNCI Cancer Spectrum) DOI: https://pubmed.ncbi.nlm.nih.gov/41569294/ 3. HYDRA/HYPNO 低分割放療試驗 DOI (HYDRA): https://pubmed.ncbi.nlm.nih.go...

ENT Update, Episode 47 | 2026/05/25. ENT Head and Neck Medicine latest information.

ENT Update Podcast 特輯 - 2026/05/23 睡眠外科最新進展 主持人：傅醫師（Puck）& 林醫師（Leda） 討論主題： 1. THN3：pHGNS 三年追蹤結果 — Chest 2026 2. OSA手術門診心血管健康 — Laryngoscope 2026 3. HGNS 反應預測 — JAMA Otolaryngol 2026 4. 形態量測取代DISE — OTO Open 2026 5. 頭頸癌存活者OSA盛行率83.7% 6. 睡眠外科與全身健康 7. GLP-1 RA 與睡眠外科 修復版：正確outro時間點、無尾音雜音

ENT Update Podcast 特輯 - 2026/05/23（週六：人工智慧在耳鼻喉科應用）修復版 主持人：傅醫師（Puck）& 林醫師（Leda） 討主題： 1. ChatGPT-5 vs ENT主治醫師 — Egyptian J Otolaryngol 2. Emory AI 語音喉癌檢測 — 93%準確率 3. Flinders Multimodal AI 中耳炎診斷 4. ML預測頭頸癌ENE — Laryngoscope 5. AI Chasm分析 — Nature npj Digital Medicine 6. Lightweight DL鼻息肉分類 — Edge computing 7. Stanford 睡眠AI穿戴裝...

ENT Update, Episode 44 | 2026/05/22. ENT Head and Neck Medicine latest information.

ENT Update, Episode 43-Special | 2026/05/21. ENT Head and Neck Medicine latest information.

ENT Update, Episode 42 | 2026/05/20. ENT Head and Neck Medicine latest information.

ENT Update, Episode 41 | 2026/05/20. ENT Head and Neck Medicine latest information.

ENT Update Podcast - 2026/05/21 (週四：睡眠醫學專題) 討論主題：睡眠呼吸中止症最新治療選擇 重點整理： 1. AD109 口服藥 Phase 3 SynAIRgy 成功 — AHI下降55.6%，已送FDA (AJRCCM, May 18 2026) 2. Zepbound (tirzepatide) 首個FDA核准用於肥胖型OSA藥物 3. Inspire V 雙側舌下神經刺激器 — 新一代植入裝置 4. Barbed Suture Pharyngoplasty — 倒刺縫線咽喉整形術 5. Solriamfetol — 改善OSA白天嗜睡 製作：洪士涵醫師

ENT Update, Episode 39 | 2026/05/20. ENT Head and Neck Medicine latest information.

ENT Update Podcast - 2026/05/19 (週二：耳科與聽力學專題) 討論文獻： 1. Otarmeni(lunsotogene parvec) FDA Accelerated Approval - First gene therapy for OTOF hearing loss (Apr 23, 2026) 2. Envoy Medical Acclaim Fully Implanted CI - 56 patients activated (Apr 2026) 3. Osia 2 System Audiological Outcomes - Otol Neurotol (Mar 1, 2026) 4. Polygenic SNHL GWAS - Million Veteran Program, JARO (Mar 16, 2026)

本期 ENT Update Podcast（2026/5/18 週一）探討頭頸外科與腫瘤學專題。主持人傅醫師與林醫師辯證式討論以下文獻： KEYNOTE-689 — 圍手術期 Pembrolizumab 用於局部晚期頭頸癌 - NEJM 2025; DOI: 10.1056/NEJMoa2501065 - FDA 已核准用於可切除局部晚期 HNSCC 圍手術期治療 NIVOPOSTOP (GORTEC 2018-01) — 輔助性 Nivolumab 用於高風險頭頸癌 - Lancet 2026; DOI: 10.1016/S0140-6736(25)02713-7 - 3年無疾病存活率 63.1% vs 52.5%...

ENT Update 2026-05-18 頭頸部腫瘤特輯 參考文獻: 1. Lactylation-driven metabolic-immune crosstalk: CD44, APP causal risk genes in HNSCC. Front Immunol, 15 May 2026. DOI: 10.3389/fimmu.2026.xxxxx 2. Neural-derived CCL5-Treg-RAMP1 axis: perineural invasion causes immunosuppression. J Immunother Cancer, 8 May 2026. DOI: 10.1136/jitc-2026.xxxxx 3. EGFR/Cyclin D1/Bcl-2 high expression prognostic meta-ana...

ENT Update Podcast - 2026年5月17日 (一週專題回顧) 參考文獻： 1. SEOM-TTCC HNC guidelines. Clin Transl Oncol. 2026 Mar 17. 2. NIVOPOST-OP. Lancet. 2026 Jan 24. 3. Neoadjuvant chemoimmunotherapy HNC. PMID: 41842604 4. CI in Asymmetric Hearing Loss. Otol Neurotol. 2026 Mar. 5. Biologics CRSwNP. PMID: 41518424 6. THN3 pHGNS 3yr. Chest 2026 May. DOI: 10.1016/j.chest.2025.11.057 7. OSPREY pHGNS. Annals...