Eswar Krishnan, MD
Drug Development Executive
Welcome to our podcast, designed specifically for biotech executives passionate about drug development. Join us as we explore a wide range of engaging topics, from cutting-edge advancements in translational sciences to the latest regulatory updates. Let’s navigate this dynamic landscape together and stay ahead of the curve! www.drugdevelop.com
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Eswar Krishnan, MD
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Podcast-Website
Neueste Folge
18. Jul 2025
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State Of The Art in SLE: For Biotech CMOs and CSOs 18.07.2025 45:47
This podcast summarizes the therapeutic landscape and the underlying molecular understanding of the causal pathways in lupus. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.drugdevelop.com
mAbs vs CAR-T: A Head-to-Head Comparison for CMOs and CSOs 14.07.2025 29:50
CAR-T Illustration. Courtesy New Scientist A recent head-to-head study assessed the comparative effectiveness of different B-cell depletion strategies in patients with autoimmune diseases, specifically comparing protein-based therapies like obinutuzumab (OBI), blinatumomab (BLI), and rituximab (RTX) with cell-based CD19 chimeric antigen receptor (CAR) T-cell therapy . Researchers analyzed lymph no...
Type 5 Diabetes: For CMOs and CSOs 07.07.2025 5:49
This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.drugdevelop.com
B-cell depletion for autoimmune diseases: For Biotech CMOs and CSOs 06.07.2025 17:27
New B cell depleters in development may offer superior impact on the immune system, durably "reset" the immune system, potentially cure conditions like pre-Type 1 Diabetes and SLE, or allow celiac disease patients to tolerate gluten again. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.drugdevelop.com
Interleukin-6 and Cardioimmunology: For CMOs and CSOs 03.07.2025 16:27
This podcast discusses the role of inflammation, specifically interleukin-6 (IL-6) signaling, in cardiovascular diseases (CVD), including atherosclerosis and myocardial infarction (MI). We discuss the therapeutic potential of blocking IL-6 or its receptor (IL-6R) with drugs like tocilizumab and ziltivekimab, highlighting their ability to reduce inflammatory markers, such as C-reactive protein (CRP...
CAR T-Cell Therapy trials in Lupus just got a bit easier: For Biotech CMOs and CSOs 29.06.2025 48:16
This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.drugdevelop.com
Fast Approvals with FDA's Voucher Programs: For Biotech CMOs and CSOs 29.06.2025 31:52
This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.drugdevelop.com
Digital Twins For Biotech CMOs and CSOs 24.06.2025 40:59
This is an audio companion to the blog post in Substack This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.drugdevelop.com
Digital Twins for CSOs and CMOs 21.06.2025 40:59
This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.drugdevelop.com
FDAs Recent Roundtable on Cell and Gene Therapies 08.06.2025 17:46
This podcast summarizes the FDA roundtable conducted on June 6, 2025. The original source is provided here This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.drugdevelop.com
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