Brainforest Café

Dennis McKenna sits down with his old friend Dr. Cedric Baker, an ethnopharmacologist and medical herbalist who studies the ethnobotany of food across more than thirty countries. Together they take apart one of modern medicine's most stubborn assumptions: that food and medicine are separate things. From Thai kitchens where every dish is therapeutic, to the world's longevity hotspots, to the ethics...

As the psychedelic renaissance surges, wild sources are collapsing under demand—peyote takes decades to grow, safrole extraction is destroying Southeast Asian forests, and Sonoran Desert toads are being overharvested. In his book Bioengineering Enlightenment, Prof. Jeffrey Gerst proposes a radical solution: engineer yeast or fast-growing plants to produce psychedelic compounds sustainably. But at...

Dennis McKenna sits down with journalist Mattha Busby to discuss the evolving world of psychedelics, including ayahuasca, ibogaine, 5-MeO-DMT, coca policy, drug reform, and the risks and realities behind psychedelic retreats and clinics. Mattha shares stories from the front lines of psychedelic journalism and reflects on the cultural, scientific, and political forces shaping the future of consciou...

In this rich and thought-provoking conversation, Dennis McKenna speaks with philosopher Mandi Astola about Terence McKenna, psychedelics, epistemology, shamanism, and the nature of knowledge. Together they explore how psychedelic experiences can produce both genuine insight and dangerous overconfidence, why intellectual humility matters, and how science and shamanic ways of knowing can complement...

Join Dennis McKenna and Viktor Wynd for a fascinating conversation on dark fairy tales, strange museum curiosities, Papua New Guinea, storytelling, collecting, and the hidden intelligence of nature. Viktor Wynd, writer, artist, and founder of the Museum of Curiosities, shares stories from his travels, his love of folklore, and his perspective on art, books, and the living world. For viewers intere...

Legal Disclaimer: The following content explores the chemistry and history of psychoactive plants for educational research. No Medical Claims: The Brainforest Café Podcast and Dennis McKenna do not make any claims regarding the health benefits or safety of the substances discussed. Any statements made by the guest regarding physical effects or health outcomes are personal anecdotes and should not...

Join Dennis McKenna in this insightful conversation with Rebecca Lazarou as they explore the urgent need to preserve ancestral medicinal plant knowledge, the role of ethnopharmacology, and how traditional herbal wisdom can be protected for future generations. Rebecca shares the story behind her PhD research on Cypriot medicinal plants and her mission to document at-risk ethnobotanical knowledge be...

In this episode of Brainforest Café, Dennis McKenna sits down with award-winning filmmaker Greg Hemmings to discuss the transformative power of storytelling and its ability to catalyze social and environmental change. Greg reveals his personal battle with long COVID and how it led to his Rewiring the Muse project, which uses neuroscience and EEG data to track his recovery. The conversation also ex...

Dennis McKenna and OpticMystic explore humble, a graphic meditation on openness, self-questioning, books, technology, AI, love, and the ongoing mystery of what it means to be human. - - - OpticMystic a.k.a Hugo Amadeu is just a human fascinated by being alive. He intended to be an astrophysicist or an oceanographer but ended up studying graphic design and becoming a freelancer. He worked on DMT: T...

In this special crossover episode of Plants of the Gods and Brainforest Café, Dennis McKenna and Mark Plotkin explore sacred plant medicines, psychedelic science, and indigenous wisdom, moving from DMT and ayahuasca to virola snuffs, salvia, ibogaine, and beyond. Originally recorded for Mark´s Podcast “Plants of the Gods”, this rich conversation on ethnobotany, shamanic healing, and the future of...

Ethnobiologist Michael Coe returns to Brainforest Café with a special mission: to turn the spotlight onto Dennis McKenna’s lifelong dedication to ayahuasca, visionary plants, and ethnopharmacology. In this intimate conversation, Michael honors Dennis’ 54 years in the psychedelic space, from early fieldwork in the Amazon to pioneering biochemical and pharmacological research on plant medicines. The...

Discover Una Meistere’s journey from Soviet-era Latvia to becoming a bridge between indigenous plant medicines, psychedelic science, art, and Baltic traditions in this in-depth conversation with ethnobotanist Dennis McKenna. They explore ayahuasca, psilocybin mushrooms in Latvia, Amanita muscaria, and ancient sauna rituals as a kind of “Latvian ayahuasca,” touching on symbiosis with nature and how...

Michael Coe is an ethnobiologist and applied ecologist with a Ph. D. in Evolution, Ecology, and Conservation Biology. As an Assistant Professor at Tarleton State University, his teaching and research focuses on the relationships between humans, ecosystems, and traditional knowledge systems. Passionate about biodiversity and the sustainable management of natural resources, Michael brings a dynamic...

Terence McKenna was the stand‑up philosopher of the apocalypse. A cognitive libertarian. The anti‑guru who rejected authority—even his own. Twenty‑five years after his passing, the “Tryptamine Elf King” still haunts the present, reverberating through the sensorium of a new generation. Inspired by Graham St John’s definitive magnum opus, Strange Attractor: The Hallucinatory Life of Terence McKenna,...

Sharon McKenna is the director and producer of the forthcoming feature documentary, “It’s Going to Get Weirder: The Terence McKenna Story.” Sharon  is a writer, film director, and journalist whose work has appeared in a range of outlets, from several alternative weeklies to MSNBC digital, among others. Her career spans three-plus decades of network news production, investigative reporting, corpora...

Nissan started his career as a medical doctor and began his work as a general practitioner in an urban community clinic system. He then specialized in ophthalmology and practiced in a small town for 36 years. He became dissatisfied working strictly on the physical level and received training in Gestalt psychotherapy and had a small private practice. He became interested in the field of Natural Vis...

Zina Brown is the writer and director of The Faerie Rings, an upcoming narrative feature filmabout the promise of visionary plant medicines, and the cruelty of those who would outlawthem. Zina’s unique visual and narrative style has been awarded in film festivals across the world,including the Barcelona International Environmental Film Festival, Kyiv Film Festival inUkraine, Mexico City Internatio...

Kevin Reed, founder and president of the Entheogen Stewardship Project, a vital new nonprofit organization dedicated to protecting culturally significant plant and animal species sacred to indigenous communities worldwide. Kevin brings a remarkable 45-year journey as a student of psychedelic science and culture to this crucial conservation work. His path began in 1984 under the mentorship of legen...

Graham St John, PhD, is a cultural anthropologist and historian of transformational events, movements, and figures. His forthcoming book Strange Attractor: The Hallucinatory Life of Terence McKenna (MIT Press, Oct 7, 2025) is the latest among his ten books, which also include Mystery School in Hyperspace: A Cultural History of DMT (North Atlantic Books 2015). Graham is Senior Research Fellow in th...

Graham St John, PhD, is a cultural anthropologist and historian of transformational events, movements, and figures. His forthcoming book Strange Attractor: The Hallucinatory Life of Terence McKenna (MIT Press, Sep 30, 2025) is the latest among his ten books, which also include Mystery School in Hyperspace: A Cultural History of DMT (North Atlantic Books 2015). Graham is Senior Research Fellow in t...

Tony Ācworth (pronounced Ayk-worth) is a visionary herbalist, psychedelic advocate, forest guide, and self-described “wily wizard” living with his wife and five-year-old son amid the coastal rainforests of Brentwood Bay, Vancouver Island. For 15 plus years, Tony has walked the plant (and mushroom) path, logged over 5,000 clinical hours doing comprehensive intakes with patients, helping them untang...

Dr Harry Shirley has a PhD in organic chemistry and research experience at theUniversity of Oxford. His research focussed on the synthesis of biologically active chemicalsof marine origin. Having left academia some years ago, he now holds a deep passion forJungian thought. He recently published his paper “the Buddhabrot and the Unus Mundus” inthe International Journal of Jungian Studies, which exp...

Dr. Andrew Gallimore is a computational neurobiologist, chemical pharmacologist, and writer, living and working in Tokyo. He has a master’s degree in chemical pharmacology and a PhD in biological chemistry from the University of Cambridge and has held postdoctoral research fellowships in computational neuroscience at the Universities of York, Oxford, and Okinawa. He has been fascinated by the neur...

Luke served in the Marine Corps for six years and two years in the National Guard, deploying to Afghanistan with an Airborne infantry unit. After his deployment, he faced severe PTSD, a loss of purpose, and a transformative “dark night of the soul.” Seeking healing, Luke explored various modalities, eventually traveling to the Amazon basin in Peru to experience Ayahuasca. This profound encounter b...

Paul Stamets, speaker, author, mycologist, medical researcher and entrepreneur, is considered an intellectual and industry leader in fungi: habitat, medicinal use, and production. He lectures extensively to deepen the understanding and respect for the organisms that literally exist under every footstep taken on this path of life. His presentations cover a range of mushroom species and research sho...