Brainforest Café

In this episode of the Brainforest Café, Dr. Dennis McKenna sits down with Kat Maier, a registered herbalist and physician's assistant who has practiced for more than forty years and wrote the award-winning book Energetic Herbalism. Together they explore what modern medicine loses when it separates the body from spirit: how energetic traditions read the body as a living landscape (hot or cold, dam...

For nearly a century, reports of a mysterious psychoactive bolete have puzzled ethnomycologists and anthropologists alike. From the 1930s reports of "mushroom madness" in the highlands of Papua New Guinea, which drew the curiosity of R. Gordon Wasson, Roger Heim, and Albert Hofmann, to modern Yunnan, China, where accidental poisonings from undercooked culinary mushrooms cause people to reliably se...

Dennis McKenna sits down with scholar, lawyer, and philosopher Tam Hunt (UC Santa Barbara’s META Lab) to dive deep into the mysteries of consciousness, psychedelics, and the existential crossroads of artificial intelligence. Tam shares his unconventional journey, from growing up in a 1970s counterculture commune to transformative, high-dose LSD journeys in Waimea Canyon, and how these experiences...

Jonathan Dickinson, CEO and co-founder of Ambio Life Sciences and author of Ibogaine and the Bicameral Mind, returns to the Brainforest Café for part two of his conversation with Dr. Dennis McKenna. Where part one followed the personal journey, this one goes into the machinery: what ibogaine is actually doing to the mind and to the cell. - - - Jonathan Dickinson, co-founder and CEO of Ambio Life S...

Jonathan Dickinson, co-founder and CEO of Ambio Life Sciences and founder of Terragnosis, joins Dr. Dennis McKenna on the Brainforest Café for a conversation about ibogaine, iboga, and the Bwiti tradition of Gabon. - - - Jonathan Dickinson, a Mexico-licensed psychologist and former executive director of the Global Ibogaine Therapy Alliance, Jonathan helped develop the field's foundational safety g...

What if the future of ayahuasca isn’t in the hype cycle, but in safety, tradition, and real transformation? In this conversation, Sam Believ and Dennis McKenna explore Colombia’s overlooked ayahuasca lineage, the importance of set and setting, and why plant medicine may hold a key to healing both people and culture. - - - Sam Believ is the founder of LaWayra Ayahuasca Retreat and host of the Ayahu...

In this conversation, Patricia Eastman and Dennis McKenna explore the deeper meaning of psychedelic healing through the lens of ancestral wisdom, initiation, and nature-based practice. Patricia shares the story behind her book Seeding Consciousness and her vision for Hu Azores, a retreat center in Portugal designed as a healing space that integrates architecture, ritual, and circadian-aware design...

In 2003, Carlos Tanner woke up in his car underwater, having blacked out behind the wheel and driven into a river. Deep in an opiate addiction, he went to the Amazon to save his own life. What he found there became his life's work. In this episode of the Brainforest Café, Dennis McKenna sits down with Carlos, founder of the Ayahuasca Foundation in Iquitos, Peru, for a wide-ranging conversation on...

In this episode of the Brainforest Café, Dennis McKenna sits down with medicinal chemist Matt Metcalf to explore a genuinely strange frontier: testing drugs in pea seedlings and the touch-sensitive Mimosa pudica instead of in mice. Along the way they circle the question that started it all, why the opium poppy spends so much energy making opioids at all, and what those molecules might be doing ins...

Dennis McKenna sits down with his old friend Dr. Cedric Baker, an ethnopharmacologist and medical herbalist who studies the ethnobotany of food across more than thirty countries. Together they take apart one of modern medicine's most stubborn assumptions: that food and medicine are separate things. From Thai kitchens where every dish is therapeutic, to the world's longevity hotspots, to the ethics...

As the psychedelic renaissance surges, wild sources are collapsing under demand—peyote takes decades to grow, safrole extraction is destroying Southeast Asian forests, and Sonoran Desert toads are being overharvested. In his book Bioengineering Enlightenment, Prof. Jeffrey Gerst proposes a radical solution: engineer yeast or fast-growing plants to produce psychedelic compounds sustainably. But at...

Dennis McKenna sits down with journalist Mattha Busby to discuss the evolving world of psychedelics, including ayahuasca, ibogaine, 5-MeO-DMT, coca policy, drug reform, and the risks and realities behind psychedelic retreats and clinics. Mattha shares stories from the front lines of psychedelic journalism and reflects on the cultural, scientific, and political forces shaping the future of consciou...

In this rich and thought-provoking conversation, Dennis McKenna speaks with philosopher Mandi Astola about Terence McKenna, psychedelics, epistemology, shamanism, and the nature of knowledge. Together they explore how psychedelic experiences can produce both genuine insight and dangerous overconfidence, why intellectual humility matters, and how science and shamanic ways of knowing can complement...

Join Dennis McKenna and Viktor Wynd for a fascinating conversation on dark fairy tales, strange museum curiosities, Papua New Guinea, storytelling, collecting, and the hidden intelligence of nature. Viktor Wynd, writer, artist, and founder of the Museum of Curiosities, shares stories from his travels, his love of folklore, and his perspective on art, books, and the living world. For viewers intere...

Legal Disclaimer: The following content explores the chemistry and history of psychoactive plants for educational research. No Medical Claims: The Brainforest Café Podcast and Dennis McKenna do not make any claims regarding the health benefits or safety of the substances discussed. Any statements made by the guest regarding physical effects or health outcomes are personal anecdotes and should not...

Join Dennis McKenna in this insightful conversation with Rebecca Lazarou as they explore the urgent need to preserve ancestral medicinal plant knowledge, the role of ethnopharmacology, and how traditional herbal wisdom can be protected for future generations. Rebecca shares the story behind her PhD research on Cypriot medicinal plants and her mission to document at-risk ethnobotanical knowledge be...

In this episode of Brainforest Café, Dennis McKenna sits down with award-winning filmmaker Greg Hemmings to discuss the transformative power of storytelling and its ability to catalyze social and environmental change. Greg reveals his personal battle with long COVID and how it led to his Rewiring the Muse project, which uses neuroscience and EEG data to track his recovery. The conversation also ex...

Dennis McKenna and OpticMystic explore humble, a graphic meditation on openness, self-questioning, books, technology, AI, love, and the ongoing mystery of what it means to be human. - - - OpticMystic a.k.a Hugo Amadeu is just a human fascinated by being alive. He intended to be an astrophysicist or an oceanographer but ended up studying graphic design and becoming a freelancer. He worked on DMT: T...

In this special crossover episode of Plants of the Gods and Brainforest Café, Dennis McKenna and Mark Plotkin explore sacred plant medicines, psychedelic science, and indigenous wisdom, moving from DMT and ayahuasca to virola snuffs, salvia, ibogaine, and beyond. Originally recorded for Mark´s Podcast “Plants of the Gods”, this rich conversation on ethnobotany, shamanic healing, and the future of...

Ethnobiologist Michael Coe returns to Brainforest Café with a special mission: to turn the spotlight onto Dennis McKenna’s lifelong dedication to ayahuasca, visionary plants, and ethnopharmacology. In this intimate conversation, Michael honors Dennis’ 54 years in the psychedelic space, from early fieldwork in the Amazon to pioneering biochemical and pharmacological research on plant medicines. The...

Discover Una Meistere’s journey from Soviet-era Latvia to becoming a bridge between indigenous plant medicines, psychedelic science, art, and Baltic traditions in this in-depth conversation with ethnobotanist Dennis McKenna. They explore ayahuasca, psilocybin mushrooms in Latvia, Amanita muscaria, and ancient sauna rituals as a kind of “Latvian ayahuasca,” touching on symbiosis with nature and how...

Michael Coe is an ethnobiologist and applied ecologist with a Ph. D. in Evolution, Ecology, and Conservation Biology. As an Assistant Professor at Tarleton State University, his teaching and research focuses on the relationships between humans, ecosystems, and traditional knowledge systems. Passionate about biodiversity and the sustainable management of natural resources, Michael brings a dynamic...

Terence McKenna was the stand‑up philosopher of the apocalypse. A cognitive libertarian. The anti‑guru who rejected authority—even his own. Twenty‑five years after his passing, the “Tryptamine Elf King” still haunts the present, reverberating through the sensorium of a new generation. Inspired by Graham St John’s definitive magnum opus, Strange Attractor: The Hallucinatory Life of Terence McKenna,...

Sharon McKenna is the director and producer of the forthcoming feature documentary, “It’s Going to Get Weirder: The Terence McKenna Story.” Sharon  is a writer, film director, and journalist whose work has appeared in a range of outlets, from several alternative weeklies to MSNBC digital, among others. Her career spans three-plus decades of network news production, investigative reporting, corpora...

Nissan started his career as a medical doctor and began his work as a general practitioner in an urban community clinic system. He then specialized in ophthalmology and practiced in a small town for 36 years. He became dissatisfied working strictly on the physical level and received training in Gestalt psychotherapy and had a small private practice. He became interested in the field of Natural Vis...