Biology Matters

Motor neurone disease (MND)—commonly known as amyotrophic lateral sclerosis (ALS)—is progressive, heterogeneous, and still diagnosed too late for many patients. But are decades of genetic discovery, biomarker research and more targeted clinical trial design changing what researchers can ask? In this episode of Biology Matters: Solving Chronic Disease, PrecisionLife CEO Steve Gardner speaks with Br...

Long COVID and ME/CFS can affect patients in very different ways, despite being grouped under the same diagnostic labels. Different combinations of genes, biological mechanisms, and symptoms may contribute to that variation, creating challenges for research, clinical trials, and treatment development. In this episode of Biology Matters: Solving Chronic Disease, PrecisionLife Co-Founders Steve Gard...

If we can understand which biological mechanisms are driving different outcomes in different patients, how much more precise could medicine become? Take GLP-1 therapies, for example. They’re reshaping the treatment of metabolic disease, but they do not work the same way for every patient. In this episode of Biology Matters, Barry Wark, Co-Founder and Chief Strategy Officer of Ovation, breaks down...

ME/CFS and Long COVID are complex, multi-system conditions that have been difficult to diagnose, study and treat through traditional approaches. Yet standard trials keep failing because they treat heterogeneous patient cohorts as a single disease. In this episode of Biology Matters, PrecisionLife CEO Steve Gardner joins Chris Armstrong, Director of the Melbourne ME/CFS Collaboration and Scientific...

Women’s health is often discussed through the narrow lens of reproductive health. But the real scope of women’s health is much broader than that. In this episode of Biology Matters, host Rowan Gardner, Co-Founder of PrecisionLife, speaks with Chief Medical Officer, Dr. Veronique Bouchet, about why women’s health must be understood across the full spectrum of complex chronic disease. They explore w...

Myalgic encephalomyelitis, also called chronic fatigue syndrome or ME/CFS, affects an estimated 17 – 24 million people worldwide, with many more experiencing ME-like symptoms after infections such as COVID. So, why does the disease remain poorly understood, difficult to diagnose and deeply isolating? In this episode of Biology Matters, host Steve Gardner speaks with Sonya Chowdhury, CEO of Action...

Healthcare systems all around the world are under pressure, and the common denominator is chronic disease. In this episode of Biology Matters, Ray Pawlicki, Executive Chairman at PrecisionLife, and host Steve Gardner explore how a shift from reacting to illness toward diagnosing, treating, and preventing disease much earlier is the solution we need to relieve this pressure. Drawing on decades of l...

Healthcare systems around the world are under growing pressure from aging populations, rising costs, and the increasing burden of chronic disease. In the debut episode of Biology Matters, hosts Steve and Rowan Gardner, co-founders of PrecisionLife, explore why many complex diseases remain so difficult to understand and treat and the merit in answering the question, “How do we prevent people from f...

Biology Matters is a podcast about one of the biggest challenges facing modern healthcare: chronic disease. These conditions affect billions of people, account for the majority of healthcare spending, and yet remain poorly understood, difficult to diagnose, and often ineffective to treat. The result is not just a scientific problem, but a system-wide healthcare crisis. Hosted by Steve and Rowan Ga...