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The New York State Psychiatric Institute in New York City is undergoing an audit and a change in leadership following a suicide that occurred during one of its clinical trials.

A speech-language pathologist by training, Wetherby has spent more than four decades developing tools to help identify and treat autism early; now her work has taken on a more personal sense of urgency.

The mutation increases the activity of an autism-linked protein and leads to social difficulties and other behavioral differences in mice.

Children with congenital heart disease have an increased likelihood of autism. Why?

The request is energizing scientists investigating autistic people who largely don’t communicate with spoken words.

When combined with tissue-inflation methods, the microscope can image axons without the need for tissue slicing, the researchers say.

But multiple independent researchers say they are not convinced by its results, which fail to confirm high-profile findings from 2017.

The approach prompts cultured cells to correct the genetic mutation in fragile X syndrome using their own DNA repair system, but it still needs to be tested further.

Nonrandom mating — the propensity for people to partner with others who share their traits — can increase the likelihood of autism or other conditions across generations.

Mice with microglia missing receptors for the neurotransmitter serotonin since birth have too many synapses and show social difficulties in adulthood.

Whole-genome sequencing data — which include information about mitochondrial DNA — offer clues to why mutations in the same gene can lead to autism or cancer.

Many genes related to the condition play a role in the internal scaffolding of cells, and cytoskeletal disruptions can affect neurodevelopment and behavior.

Triplett gained media attention for his autism later in life, and he became the face of the effort to research the lives of older adults with autism.

A renowned researcher’s eye for detail has given her a second career and a new following.

A text-predicting chatbot parses text from conversations in a way that parallels brain-activity patterns associated with speech production and comprehension.

The journal’s decision comes two years after Spectrum covered backlash from researchers over the study.

Next-generation trackers could realize a long-standing research dream: conducting sleep studies in large numbers of autistic people.

But the alternatives, including living-brain biopsies, raise logistical and ethical questions, experts say.

Minimally verbal autistic preschoolers gained new words and phrases in a head-to-head comparison of two interventions.

Changes to the DSM-5’s diagnostic criteria for autism were meant to add clarity, but they also generated new questions.

A careful clinician who prizes evidence, Jeremy Veenstra-VanderWeele is happy to embrace trial failures, as long as he learns from them.

The drug clemastine and other compounds that fortify the protective sheath around neurons may prove therapeutic for some genetic neurodevelopmental conditions.

These scores — composite measures of a person’s autism-linked common genetic variants — cannot predict an autism diagnosis but could help researchers better understand the condition’s underlying biology.

The papers were flagged by a method that has now been called into question.

Experiments offer clues to why certain mutations are associated with autism in some people and not others.