Dr Daniel J. Guerra

Authentic Biochemistry

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Dr Daniel J. Guerra

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Science

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Último episódio

25 de out de 2026

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Episódios

Authentic Biochemistry Podcast. PTM's V. Unique Autocatalytic Cholesterylation of a HedgeHog Signaling GPCR. Dr Daniel J. Guerra 29OCTOBER24 30.10.2024

References Biomolecules. 2020 Jul 7;10(7):1008. FEBS Lett 2021.595, Issue8. Pages 1107-1131 Cell Res. 2022 Mar 2;32(4):327–328. Cell Chem Biol.2024 Jul 18;31(7):1264-1276.e7. Peterson &Lesh. 1974. "Unbroken Chain" on [Live from the Mars Hotel} lp Grateful Dead https://youtu.be/T5FN06LFfHk?si=RgFd7kBKAAJ6YKK0 Hunter&Lesh1970 "Box of Rain" on [American Beauty] lp. https://youtu.be/nxjvo4BRf-...

Protein Post Translational Modifications IV. Authentic Biochemistry Podcast Dr. Daniel J. Guerra 26October24 27.10.2024

References Signal Transduct Target Ther. 2024 Mar 15;9:60. Nature Reviews Molecular Cell Biology 2022 23 ,:715–731 Kierkegaard, S. 1846. The Present Age. Jon Anderson, Chris Squire, and Bill Bruford 1971. "Heart of the Sunrise" on Fragile [lp] Tartini, G. 1730. Concerto for Clarinet and Strings https://open.spotify.com/track/07ZIuFZe7LCkOsAZURkRqs?si=eb4c096081854068

Dolichol-PP Driven ER Glycosyl PTM’s Authentic Biochemistry Podcast Dr. Daniel J. Guerra 21October24 22.10.2024

References Clin Biochem. 2007 Jun;40(9-10):575-84 Endocr Metab Immune Disord Drug Targets. 2023;23(2):235-241. Guerra, DJ.2024. Lectures. Welch, R. 1971. "Future Games" Fleetwood Mac https://open.spotify.com/track/021JldNpXGATNSC69edcBT?si=0f29d7047e9d4eb0 Vivaldi, A. 1723. "Autumn" https://youtu.be/Z21_VpNipfg?si=ZXVDkCSFUz-JbhrE

Protein PTM Diseases Associated with Epigenetic Phenomena II Type I Diabetes and lncRNA’s. AUTHENTIC BIOCHEMISTRY PODCAST.DR DANIEL J. GUERRA.18 OCTOBER 2024 19.10.2024

References Front Endocrinol (Lausanne). 2022;13: 822221 Bach, J.S. 1721. Brandenburg Concert 2. BMV 1047 https://open.spotify.com/track/38OfejDZKqrUstmOpCw6D3?si=5e8eee6b6d974f97

Protein PTM Diseases Associated with Epigenetic Phenomena I. AUTHENTIC BIOCHEMISTRY PODCAST.DR DANIEL J. GUERRA. 15 OCTOBER 2024. 16.10.2024

References J Exp Clin Cancer Res. 2022; 41: 100. Front Endocrinol (Lausanne). 2022;13: 822221 Hunter-Garcia. 1968. "Dark Star" from [LiveDead;lp.] https://open.spotify.com/track/07CwWCJetytT1cSnQOgRMU?si=dc538f19db52489a Beethoven, LV. 1801. "Moonlight Sonata" #14 in C Sharp Major https://open.spotify.com/track/506fPIwbFyyvHp2PpFJj2e?si=0dcb00e6d9c14488

Sarcopenia XVII Fine. Authentic Biochemistry Podcast. 12October 24 Dr Daniel J. Guerra. 13.10.2024

References Am J Physiol Cell Physiol 2019 Sep 1;317(3):C502-C512 Browne, J. 2002."Dont You Want to be There?" https://open.spotify.com/track/2e62rpQnEaVoQHWltXWDVV?si=8ba86ab27eeb4972 Simon, P. 1970. "The Boxer" https://open.spotify.com/track/76TZCvJ8GitQ2FA1q5dKu0?si=db43bb95e8504819 Biber, HIF von. 1681. Sonata 8 https://open.spotify.com/track/56hzAmdRl7ndN95YFeksUQ?si=0128734522544c1e

Authentic Biochemistry Podcast. Sarcopenia XVI. Phosphatidic Acid and the mTORC axis of Muscle Protein Translation.DJGPhD10 October 24 11.10.2024

References Appl. Physiol. Nutr. Metab. 40: 1233–1241 (2015) BMC Biology 2011. 9:85 FEBS J. 2024. May. Volume291, 9. :1870-1885 Haydn, M. 1771. Requiem in C. Moll https://youtu.be/RpS3ZPynlvw?si=pEJueW9E-KTgA8H0

Authentic Biochemistry Podcast Sarcopenia XV Dr. Daniel J. Guerra 09OCTOBER24 10.10.2024

References Sports (Basel). 2021 Sep; 9(9): 127 Physiol Rep. 2021 Sep; 9(18): e15031 J Physiol. 2023 Feb;601(3):419-434 BMC Genomics. 2022; 23: 519. PLoS One. 2008; 3(1): e1385. Miller, S. 1970. "I Love You". Steve Miller Band V (lp) https://youtu.be/sM1zPxR3K2U?si=gp3IXDjUtF2RLjWJ

Authentic Biochemistry. Sarcopenia XIV. Dr Daniel J. Guerra 08October24. 09.10.2024

References Biosci Rep. 2022 Jun 30; 42(6): BSR20211854 Bone. 2022-11-01, Volume 164, Article 116539 Satie. E.1890. Gnossiene No 1 https://open.spotify.com/track/4820SC1xnUaabzzYQTDkP2?si=cd7a6ed41db24a17 Bach. JS 1726..Cantata BMW. 169 https://open.spotify.com/track/50dM4aKwuItH59JC96Y0bI?si=b3d8f5c80b3f48b7

Authentic Biochemistry Podcast. Sarcopenia XIII Lipid Utilization via Perilipin/CD36 and Spatiotemporal Framing. Dr Daniel J Guerra 07OCTOBER24 08.10.2024

References Biosci Rep. 2022 Jun 30; 42(6): BSR20211854 Nature Reviews Endocrinology 2018. volume 14:452–463 Bone. 2022-11-01, Volume 164, Article 116539 Beethoven LV. 1806. Violin Concerto in D Major OP 61 https://youtu.be/rhdXr9l5gPM?si=0WcFfHzKajylaUBA Hunter-Garcia. 1973 Row Jimmy on [Wake of the Flood;lp] https://youtu.be/B4k9XfHBVEE?si=T3mXTER0Nvh2cccG

Authentic biochemistry Sarcopenic Lipid and Oxidative Metabolism XII Dr Daniel J Guerra 04OCTOBER24 05.10.2024

References Nutrients 2021 . April 13:5 Bone 2022-11-01, Volume 164, Article 116539 Nat Rev Mol Cell Biol. 2020 Jul;21(7):363-383 Hunter-Garcia.1973 "Stella Blue" From [Wake of the Flood;lp] https://youtu.be/VKsWDyvWaL4?si=f6Fx7gWhXaed1ua3

Sarcopenia XI The Membrane Lipid Domains Dr Daniel J. Guerra.03October24 03.10.2024

References Genes Dis 2023 Nov 27;11(6):101180 Nat Rev Mol Cell Biol. 2020 Jul;21(7):363-383 Front Mol Biosci. 2021; 8: 728777. Mozart WA. 1778-82. Symphonies 31 32 34 and 35 https://open.spotify.com/album/6OSV42bbN9NFwtq38a1MH9?si=bqGtsKfwQReswUmxSb69zQ

Authentic Biochemistry Podcast Sarcopenia X Senescence Dr Daniel J. Guerra 30September24 01.10.2024

References Mech Ageing Dev.2021 Dec:200:111595. Open Biol. 2021 Dec; 11(12): 210110. Mol Metab.2023 Jan; 67: 101652 Genes Dis 2023 Nov 27;11(6):101180 Grisman, D. 1975 "Old and in the Way" https://open.spotify.com/track/1vao1Gy21m3KwPMgTbfhrG?si=4e3843aa556341b7

Sarcopenia IX. The Interplay of quinone reductase and PGC1-alpha in mitochondrial event dynamics. Dr. Daniel J. Guerra. 28.9.24 29.09.2024

References Nature Communications 2024. volume 15,1541. Campbell, Ian. 1963. The Sun is Burning. https://youtu.be/3L2Tn-YFlKk?si=pFTaj6iG9q4x-LR7

Sarcopenia VIII. Parkin expression in adipose linked to bioenergetics and mitochondrial fate associated muscle metabolism. DJGPhD.25.9.24 26.09.2024

References Nat Commun. 2022; 13: Article Number:6661. Nature Commun. 2024; 15: Article number:1541 Myrow and Gordon 1946. You Make Me Feel so Young. Sinatra https://open.spotify.com/track/6N1amIkGGddramWRDrP3Nm?si=0de15d2fec054455 Mozart WA. 1773 Symphony 24 in G minor. K.183 https://youtu.be/707oHEGF6l8?si=E_1zWSSN5zRAHs9i

Sarcopenia VII Authentic Biochemistry Podcast. Dr Daniel J. Guerra 23.9.24 24.09.2024

References Endocr Rev. 2020 Aug; 41(4): 594–609. Sci Signal. 2017 Jan 31; 10(464):eaaf7478. Nat Commun. 2022; 13: 6661 Acta Physiologia (OXFORD) 2024.  Volume240, Issue3March.e14111 Cell Metab. 2022 Dec 6; 34(12): 2036–2046.e8.

A Dialectical Eventual Disclosure of Metabolic Temporality. Dr Daniel J. Guerra. 21Sept24. Authentic Biochemistry Podcast 22.09.2024

References Plato  360 BC. "Timaeus" Plotinus  250 AD. "Ennead III" St Augustine 426 AD. Des Religiones. Guerra, DJ. 2024 manuscript in preparation Von Bingen, H. 1174. Various compositions in "Plainchant" https://open.spotify.com/album/6E5bJgcbFNZDqTnYAOxDFw?si=gQcsyjwjQquOPAbA_Oud1A

Authentic Biochemistry Podcast. Sarcopenia VI. Dr Daniel J. Guerra 19. 9.24 19.09.2024

References Front. Physiol. 2021. 02. June. Vol.12 Nature Aging 2021. volume 1, pages 60–72 Teleman, JF. 1723 . "Wassermusick" Concerti TWV 55:C3 https://open.spotify.com/album/7cbAYEr4FJf8fAG6upSFgL?si=E_gnKD4QRUuu7xqhSpt9fQ Hayward, J. 1967. "Nights in White Satin" Moody Blues. https://open.spotify.com/track/6L5BZEcZmD6RBJnimzlyKr?si=4d8a0d1e77494b98

Authentic Biochemistry Podcast Sarcopenia V. Dr. Daniel J. Guerra 16.9.24 17.09.2024

References HORMONES 2013, 12(2):172-191 Eur J Endocrinol. 2017 176(5): R235–R246 Amino Acids. 2012 Oct;43(4):1803-7 Cell Metabolism  2020 31472-492DOI Kirwain, D. 1972 "Dust" Fleetwood Mac [Bare Trees lp.] https://open.spotify.com/track/2yE8gE3zBfflRklTKIlpiv?si=d1cbe70445c34fa6

Sarcopenia IV. The CH20 Signaling Metabolome Circuit Involving the CNS, Liver, Adipose and Skeletal Muscle. Authentic Biochemistry Podcast Dr. Daniel J. Guerra 14.9.24 15.09.2024

Guerra, DJ. 2024. lecture notes Leach, Donovan. 1967 "Mountain Jam" Allman Brothers https://youtu.be/w9ZubobGMLs?si=uHLon1CvCiCSiqtX

Authentic Biochemistry Podcast Sarcopenia.C.3 AMPK Control over Pyrimidine and Purine biosynthesis via mTORC. Dr. Daniel J. Guerra. 11Sept24 12.09.2024

References Experimental & Molecular Medicine.2016. volume 48, 224 Nature Metabolism 2023. volume 5, pages 277–293 Nature Reviews Drug Discovery 2019. v18. : 527–551 Pisendal . JG. 1730's. Violin Concerti. https://open.spotify.com/album/6dC3dq8i6rDeeKtz5LyhFZ?si=jUsRMIraR7-zO5o0UQGMdw

Sarcopenia C.2 Authentic Biochemistry Podcast. Dr Daniel J. Guerra. 10Sept24 11.09.2024

References Acta Physiologica (Oxford)2024. V.240.Issue 3 e14107 Hum. Mol. Genet. (2016) doi: 10.1093/hmg/ddw252 Amino Acids. 2016 Aug;48(8):1793-805. European Journal of Applied Physiology 2013, Volume 113, Issue 4, pp 987–996 Lennon-McCartney. 1969. "Carry that Weight" from Abbey Road lp. https://open.spotify.com/track/5eZrW59C3UgBhkqNlowEID?si=cddd237e073047c8 Anderson and Howe. 1973....

Sarcopenia Molecular Pathology. Dr. Daniel J. Guerra. 09Sept24. Authentic Biochemistry Podcast 10.09.2024

References Acta Physiologica (Oxford)2024. V.240, Issue 3 e14107 Int. J. Mol. Sci. 2023, 24, 5564 Simon, Paul and Bruce Woodley. 1966.The Cyrkle. "Red Rubber Ball" https://open.spotify.com/track/6DuLN8tFW0DkH9wsbTHZsX?si=3bc8b99f3ae34ac6 Robert Fripp, Ian McDonald, Greg Lake, Michael Giles, Pete Sinfield English 1969. "Court of the Crimson King" King Crimson https://open.spotif...

Concerning Technical Difficulties on the Recent Video Lectures.DJGPhD.08Sept24. 08.09.2024

References Previous discussions

Authentic Biochemistry Podcast. Alzheimer’s Disease coda. Dr Daniel J Guerra.04sept24 05.09.2024

Correction: In my lecture I incorrectly used the W single letter designation as representing tyrosine. I miss-spoke . W=tryptophan while Y=tyrosine. The WW domain discussion is important for specific protein:protein interactions wherein the tryptophan (W) residues (found in the beta1 and beta 3 folds) are separated by 20 -22 amino acids that contain certain tyrosine (Y) residues in the beta2 regio...

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