We're not getting any younger... yet.

Aging appears to progress similarly across species, from worms and flies to mice and humans, and involves pathways related to early development. Guest Linda Partridge talks with Gordon while visiting the Buck Institute to discuss the evolutionary trade offs of aging mechanisms, the role of nutrient-sensing pathways, and how we might get the most benefit from preventative interventions in midlife....

Following the episode with Rhonda Patrick, Gordon and Stella discuss the complex relationship between stress and aging, and preview the next conversation with Linda Partridge. The show will return in January 2023. Happy Holidays! Support the show

What is the relationship between stress, metabolism, and aging? How can we use “good” stress to enhance our ability to weather the challenges of getting older? Guest Rhonda Patrick has investigated the biology of aging and related lifestyle interventions throughout her multifaceted career. In this episode she joins Gordon to explore insights from studies on nutrition, exercise, inflammation, psych...

Gordon and Stella revisit the discussion with Judy Campisi to understand the role senescence plays in aging, and look forward to the next conversation with longevity expert Rhonda Patrick. Support the show

Dr. Campisi has been at the forefront of studying cellular senescence for decades, revealing the mysteries of these not-exactly-dead cells and their role in many diseases of aging. In this episode, she joins her colleague Gordon to discuss the characteristics and function of senescent cells, as well as promising interventions on the horizon. Judy also describes how to get lucky in science by being...

Gordon and show editor Stella revisit highlights from the conversation with David Sinclair, and get ready for the next episode with Judy Campisi. Support the show

Is life essentially an information process driven by biochemical interactions? If so, can we simply correct any errors in that process? In this episode, renowned researcher and author David Sinclair joins Gordon to dive into the startling insights from applying information theory to aging. Topics include epigenetics, sirtuins, metabolism, and why we might not want to kill all the zombies.  Support...

Host Gordon and show editor Stella connect over Zoom to discuss the highlights of Gordon’s conversation with Steve Austad, the renowned biologist, and look ahead to the next episode with David Sinclair. Support the show

When we think of aging, we typically think of human aging, but the biological processes that cause cellular damage are shared by many species. Few people have investigated the biology of aging across the animal kingdom as deeply as researcher and author Steve Austad. In our first episode, Steve and host Gordon Lithgow explore some fundamental questions: What makes some animals live longer than oth...

Introducing a new podcast from the Buck Institute for Research on Aging: We're not getting any younger... yet . Join host Gordon Lithgow to investigate the biology of aging in interviews with leading researchers from across the field. Subscribe to download new episodes each Wednesday. Support the show