by Redpoint Ventures
Vital Signs with Jacob Effron and Nikhil Krishnan
On Vital Signs, Jacob Effron and Nikhil Krishnan dig into cutting-edge trends in healthtech and the people shaping them. Every two weeks they’ll explore a new sub-sector and trend with policy leaders, startup founders and industry executives. Subscribe now to make sure you don’t miss any of it!
Author
by Redpoint Ventures
Category
Podcast website
Latest episode
Jun 24, 2026
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Episodes
Ep 19: Mike Kopko on ACO Reach and The Future of Health Exchanges 28.03.2023 37:43
Jacob and Nikhil sit down with Mike Kopko, CEO and co-founder of Pearl Health to discuss Pearl’s care model and what it’s been like building the company as ACO Reach evolved. Mike also shares some great stories negotiating claims in the early days of Oscar.
Ep 18: Dr. Jeffrey Kang on CVS/Walgreens' Role in Healthcare and The Future of Risk Adjustment and Senior Care 16.03.2023 39:11
Jacob and Nikhil sit down with Dr. Jeffrey Kang, CEO of WellBe Senior Medical, and former President of ChenMed, SVP Health and Wellness Solutions at Walgreens, CMO at Cigna, CMO at CMS and CEO of Urban Medical Group. They discuss risk adjustment, retailers in healthcare and how healthcare has/hasn't changed since his work doing risk-based care for complex patients and at CMS in the 80s and 90s.
Ep 17: Naomi Allen on How to Sell to Employers and the Future of Mental Healthcare 01.03.2023 49:07
Jacob and Nikhil sit down with Naomi Allen, CEO and founder of Brightline (child and teen focused mental health company that’s raised >$100M) and Castlight/Livongo exec. They discuss the difficulties of balancing employer customers and employee satisfaction at Castlight, how Livongo captured member delight and Brightline's care model.
Ep 16: Dr. Jaewon Ryu on Geisinger's Fresh Food and DNA Sequencing Programs and the Future of Clinician Training 14.02.2023 39:27
Jacob sits down with Geisinger CEO Dr. Jaewon Ryu to discuss how he and Geisinger think about their Fresh Food Farmacy, population-wide DNA sequencing efforts, and transforming medical education.
Ep 15: Dr. Jenny Schneider on What Livongo Got Right and Improving Rural Healthcare 02.02.2023 26:43
Jacob sits down with Homeward Health CEO and former Castlight and Livongo CMO Dr. Jenny Schneider to discuss solving provider shortages in rural markets, how tech can/can’t help care and what Livongo did to make coaching more effective.
Ep 14: Vijay Kedar on Oscar Reflections and What's Required to Make At Home Care Work 19.01.2023 41:01
Jacob and Nikhil sit down with Tomorrow Health CEO and former Oscar Texas GM Vijay Kedar to discuss lessons he learned at Oscar, reflections on the ACA market, the nuances of operationalizing at home care and what Tomorrow is building.
Ep. 13: Annual Predictions and Robin Shah and Dr. Bobby Green on Designing New Cancer Care Models and The Future of Oncology 05.01.2023 36:58
Jacob and Nikhil discuss annual health-tech predictions and are then joined by Thyme Care co-founders Robin Shah and Dr. Bobby Green to discuss the nuances of taking risk in oncology, lessons on selling to providers, and what they're building at Thyme Care. 0:00-9:10 Jacob & Nikhil discussion 9:13-end Thyme Care founders interview with Robin Shah and Dr. Bobby Green
Ep 12: Chris Gibson on Building a Platform Biotech and The Future of R&D 14.12.2022 39:19
Jacob sits down with Chris Gibson, the co-founder and CEO of Recursion, to discuss how Recursion predicted drugs that would be effective for COVID, his take on different techbio business models, what pharma R&D will look like in 25 years and more.
Ep 11: Dr. Arif Nathoo on the Evolution and Future of Healthcare Data and Building a Vertical SaaS Platform 29.11.2022 40:45
Jacob sits down with Dr. Arif Nathoo, the CEO of Komodo Health (most recently valued at $3.3B) to discuss Komodo’s journey from a single app to a platform, why EHR data is overhyped and where healthcare data is headed.
Ep 10: Dr. Bob Kocher on the Future of Health Systems and Increasing Healthcare Productivity 16.11.2022 49:22
Jacob and Nikhil sat down with Dr. Bob Kocher, the Venrock partner who helped write the Affordable Care Act while in the Obama administration to discuss how health systems will increase productivity, what drives healthcare costs, and his reflections on the ACA.
Ep 9: Eren Bali on Using Tech to Lower Healthcare Costs and Carbon Health's Strategy 27.10.2022 52:13
Jacob and Nikhil sit down with Carbon Health CEO and founder Eren Bali to discuss Carbon Health's evolution, how he thinks about Carbon Health's tech, partnerships and expansion and what policy changes he thinks would improve healthcare.
Ep 8: Dr. Sachin Jain on Incubating Businesses and Why Health Systems Will Drive Value-Based Care 11.10.2022 45:55
Jacob and Nikhil sit down with Dr. Sachin Jain to discuss operating as a non-profit, competing in Medicare Advantage and when PE/VC backing doesn’t make sense. He also shared some hot takes on new people entering healthcare and the importance of health systems in driving the move to value-based care.
Ep 7: Seema Verma on Running CMS During COVID and Drug Pricing 27.09.2022 34:53
Jacob sits down with Seema Verma to talk about rapid policymaking during COVID, recent drug pricing legislation, her reflections on her time at CMS and what areas of tech she's most excited about.
Ep 6: Nikhil Krishnan on Doctor Influencers and Healthcare Hot Takes 13.09.2022 44:42
Jacob sits down with Nikhil Krishnan, founder of Out of Pocket, to discuss his path to becoming a healthcare meme king and the community he's building to get more people into healthcare and make it easier to start health tech businesses. They also hit on Nikhil’s thoughts on physician payment, big tech in healthcare and more.
Ep 5: Lucia Huang on Psychedelic Medicine and the Future of Mental Healthcare 31.08.2022 34:25
Jacob sits down with Lucia Huang, co-founder and CEO of Osmind, to discuss new psychedelic and neuromodulation mental health treatments, how Osmind is furthering research around them, and what’s next for the space.
Ep 4: Brad Smith on Improving Policy and Rural Healthcare 16.08.2022 39:13
Jacob sits down with Brad Smith, founder of CareBridge, Main Street Health and Aspire and former head of CMMI, to discuss the novel ways he’s bringing risk-based models to rural healthcare and Medicaid and hear why he thinks CMMI programs haven’t worked to date.
Ep 3: Dr. Tom Lee on Amazon/One Medical, Galileo and Healthcare's Future 03.08.2022 41:15
Jacob sits down with Dr. Tom Lee founder of One Medical, Galileo and Epocrates. They discuss Amazon’s $3.9B acquisition of One Medical, what Tom’s building at Galileo and the future of medical education.
Ep 2: Dr. Mandy Cohen on Medicaid Innovation and Succeeding Under Risk 19.07.2022 30:34
Jacob sits down with Dr. Mandy Cohen - former Secretary of North Carolina’s Department of Health and Human Services, COO of the Center for Medicare & Medicaid Services and current CEO of Aledade’s newest business line Aledade Care Solutions. They discuss her work in North Carolina around Social Determinants of Health, how Medicaid policy and innovation works, the new business line she’s building a...
Ep 1: Adam Boehler on the Value Based Care Market and What's Next 05.07.2022 29:27
Jacob sits down with Adam Boehler - former CEO of Landmark Health, Head of the Center for Medicare and Medicaid Innovation and current CEO of Rubicon Founders. They discuss how building a value-based care business has changed, how Adam came up with the idea for Landmark and his other businesses, what makes different patient segments a fit for value-based models and where the space is headed. They...
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