UC San Diego (Audio)

Curious about the secret to staying young? Rob Signer shares insights into how our bodies age, focusing on the role of stem cells and a critical protein called HSF1 that helps them cope with stress. Signer explores the delicate balance of keeping these cells healthy without increasing cancer risk and highlighted some promising progress in enhancing the cells' ability to manage waste. Series: "Exce...

The human body has traits that evolved at different times, from 1.5 billion to 2 million years ago, each bringing health benefits and risks. Multicellularity enabled organs and cancer. The immune system defends us but can cause inflammation. Breastfeeding supports infant health but relates to breast cancer risk. Menstruation and invasive placentas improved reproduction but led to pain and cancer r...

Cancer is normal development spun out of control. It is the great plasticity and power of development, without the overarching controls that guide normal development toward an integrated adult form. Instead, whenever a newly developed kind of tissue acquires the ability to survive, grow, and resist control, there is nothing to stop it. That may be why normal adult cells are often terminally differ...

Fadel Zeidan, Ph. D., discusses the science of mindfulness and how meditation can change the brain. He explains what happens in the brain during stress, how mindfulness helps us become more self-aware, and why it's important to pay attention on purpose. Zeidan shares easy ways to bring mindfulness into daily life, even in small moments. The video includes guided meditations led by Zeidan. Viewers...

Yaron Singer, Vice President of AI and Security at Cisco, co-founded a company specializing in artificial intelligence solutions, which was acquired by Cisco in 2024. They developed a firewall for artificial intelligence, a tool designed to protect AI from making critical mistakes. No matter how sophisticated AI is, errors can still happen, and these errors can have far-reaching consequences. The...

Metamaterials are special structures made of tiny components that give them unique electromagnetic properties not found in nature. One key feature is a negative refractive index, which enables technologies like "superlenses" for ultra-detailed imaging and "invisibility cloaks." The concept began when Sir John Pendry theorized special rings (SRRs) that could manipulate electromagnetic waves. Later,...

The 3rd Annual Global Astrobiotechnology Hub focuses on advancing the intersection of space exploration, biotechnology, and innovation. The program brings together scientists, researchers, and space professionals to discuss how space technologies can accelerate scientific breakthroughs, particularly in fields like personalized medicine and bioengineering. Key themes include the challenges of condu...

A Parent’s Guide to San Diego Schools is a valuable, research-driven resource that helps families navigate school choices with confidence. This year, the guide takes a deeper look at the powerful role Career Technical Education (CTE) plays in shaping student success beyond the classroom. In a discussion led by Morgan Appel of UC San Diego, Andrea Lopez-Villafaña and Jakob McWhinney of Voice of San...

Scientists, leaders, and patients discuss the intersection of cutting-edge science and real-world impact. They explore the importance of patient perspectives in shaping medical advancements and how collaboration fuels groundbreaking research. Key scientific achievements in areas like regenerative medicine, cancer therapies, and space biology are highlighted. The group emphasizes the need for scien...

Paul Hoffman is the 2024 Kyoto Prize Laureate in Basic Sciences. He is an adjunct professor at the University of Victoria, has conducted groundbreaking research in the “Snowball Earth” (global freezing) hypothesis and plate tectonics occurring in the first half of the Earth’s 4.6-billion-year history. After earning his doctorate from Johns Hopkins University, Hoffman served the Geological Survey o...

William Forsythe is the 2024 Kyoto Prize Laureate in Arts and Philosophy. He is a choreographer whose work has extended ballet to a dynamic contemporary art form. In 1984, he began a 20-year tenure as director of Ballet Frankfurt. After the closure of the Ballet Frankfurt in 2004, Forsythe established a new, more independent ensemble, The Forsythe Company, which he directed from 2005 to 2015. Betw...

Sir John Pendry is the 2024 Kyoto Prize Laureate in Advanced Technology. He serves as a professor of Theoretical Solid State Physics at Imperial College London. After earning his Ph. D. at University of Cambridge, Pendry’s initial research concerned a low-energy electron diffraction theory for examining and measuring the surface of materials for practical purposes. He theoretically demonstrated th...

The meteorology that causes atmospheric rivers is complex, but scientists at the Center for Western Weather and Water Extremes (CW3E) are working to help better predict them and understand what they mean for rainfall and snowfall across the state. Join CW3E Deputy Director Julie Kalansky to learn the causes and consequences of these rivers in the sky. Series: "Jeffrey B. Graham Perspectives on Oce...

Cervical cancer remains a significant public health concern, but innovative approaches and community-based research are transforming prevention efforts, particularly immigrant communities. With over 600,000 new cases diagnosed annually, early detection and prevention strategies are crucial. However, accessibility and awareness gaps persist in immigrant communities due to language barriers, cultura...

How can you make choices today that could help you live longer and feel better? Gordon Saxe, M.D., Ph. D., explores the ways to slow the aging process and live a healthier life. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40601]

“When anchors fail, people die.” This line has many meanings for author, motivational speaker and expert mountain climber Manley Feinberg. In this Osher Author Talk interview, Feinberg describes a harrowing climb of Yosemite's El Capitan in 2022, where he and his son saved the life of their companion while suspended on the face of the mountain. He incorporates his experience climbing mountains int...

Jesmyn Ward has been hailed as the standout writer of her generation, proving her “fearless and toughly lyrical” voice in novels, memoir, and nonfiction. She's been called “the new Toni Morrison.” Ward is a MacArthur “Genius Grant” recipient and in 2017, she became the first woman and the first person of color to win two National Book Awards for Fiction—joining the ranks of William Faulkner, Saul...

John A. Pérez, Regent Emeritus of the University of California, sits down with Robert Williams, Ph. D., CEO and Finci-Viterbi Executive Director of the USC Shoah Foundation, for a critical conversation about the rise of antisemitism on college campuses. They explore how history shapes present-day challenges, the dangers of misinformation, and the role of higher education in confronting hate. Drawi...

Sandra Cisneros is a Latina American short-story writer and poet regarded as a key figure in Chicano literature. She is best known for her first novel, "The House on Mango Street," and her subsequent short story collection, "Woman Hollering Creek and Other Stories." Her work experiments with literary forms that investigate emerging subject positions, which Cisneros herself attributes to growing up...

OpenAI researcher Adam Kalai sits down with UC San Diego professor Mikhail Belkin to discuss his work in machine learning, algorithmic fairness, and artificial intelligence. Kalai has contributed research in areas like fairness in AI models, word embeddings, and human-AI collaboration. He has worked at Microsoft Research and has published influential papers on bias in machine learning models. His...

Human beings show a range of emotional attachment, affection, and infatuation often referred to as “love”. Love promotes long-lasting and secure relationships that involve nurturing and support. Biological mechanisms underlying such behavior involve ancient neuropeptides and their receptors in the brain. These systems are also involved in reproduction, ranging from mating and pair-bonding, to givi...

Human fathers exhibit hormonal shifts in testosterone, prolactin, and oxytocin, enabling flexible responses to parenting. In species with costly paternal care, these shifts balance mating and parenting efforts, suggesting evolved neuroendocrine capacities that support fatherhood. Today, fathers collaborate with mothers worldwide, though their roles vary across cultures and family systems, much as...

Author, screenwriter, philanthropist, journalist and broadcaster Mitch Albom is an inspiration around the world. He is the author of numerous books of fiction and nonfiction, which have collectively sold more than 40 million copies in 48 languages worldwide. He has written eight number-one New York Times bestsellers — including "Tuesdays with Morrie," the bestselling memoir of all time. As part of...

The titi and owl monkeys of South America live in socially-monogamous groups where the male and female establish a pair bond and share parental duties. Why do males of these species mate in a monogamous relationship presumably foregoing other reproductive opportunities? And why are titi and owl monkey males such good fathers, investing heavily in the care of offspring that they cannot be certain t...

Anthony Lim, M.D., J.D., explores how small, intentional steps can lead to lasting behavioral change. Lim breaks down a simple, four-step framework to help people achieve their goals, whether it's improving health, forming better habits, or making positive life changes. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40602]