Tiny Matters

In 2021, 80,411 people in the United States died of an overdose involving opioids, making up 75% of all drug overdose deaths that year. That’s also 10 times as many opioid overdose deaths as in 1999. How did we get here? In this episode, Sam and Deboki trace the origins of opioids, from opium and morphine to fentanyl, and scrutinize the significant role pharmaceutical companies played in kick star...

We often hear that dogs help lower our blood pressure, decrease our allergy risk, and even alert us to disease. But is there science behind those claims? In this episode of Tiny Matters, Sam and Deboki unpack some dog domestication history and fascinating research with Jen Golbeck and Stacey Colino, authors of the new book, The Purest Bond: Understanding the Human-Canine Connection. Links to the T...

Happy spooky season, Tiny Matters listeners! In today’s episode, Sam and Deboki tackle two Halloween themed topics: The Salem witch trials and mummies.  In 1692 and 1693 a series of hearings and trials took place in Salem, Massachusetts, leading to 19 people being executed, marking the last executions for witchcraft in the United States. Sam and Deboki speak with a researcher who has spent over a...

A couple weeks ago, NASA did something they’d never done before: they collected material from an asteroid and brought it back to Earth. These samples — harvested as part of the OSIRIS-REx mission — could tell us more about our planet's beginnings and even reveal information about the origins of life. But collecting samples from space doesn't come without risk. In this episode, we delve into the he...

Why do we need an influenza vaccine every year when there are many vaccines we only need to get once every few decades? In this episode, Deboki and Sam kick things off by covering the different strains of influenza that are most likely to cause, or already caused, pandemics. They also chat with experts about the new, more deadly strain of avian influenza — H5N1 — that has been making its rounds in...

This episode is outside the Tiny Matters norm — it’s a Q&A and mug giveaway! Sam and Deboki answer listener questions about science, like, ‘Can parasitic hookworms cure allergies?,’ ‘How do you measure the end of the universe?,’ ‘What’s the science behind why we can’t stand nails on a chalkboard,’ plus questions about making the leap into science communication, including podcasting. They wrap...

Flavor and taste are not the same thing. In this episode of Tiny Matters, Sam and Deboki explain why, and unpack the important role flavor plays in health. They also chat with experts about ways of making the foods you don’t like more appealing. The Tiny Show & Tell stories are here and here . And to support Tiny Matters, pick up a mug here! Check out The Weirdest Thing I Learned This Week her...

Colonialist practices, past and present, combined with climate change are having catastrophic effects on poorer countries in the global south. In this episode, Sam and Deboki talk with experts about how and why that’s the case and unpack two major examples of this impact: the 2022 Pakistan floods and the global factory, particularly the garment industry. Laurie Parson's book is here . The organiza...

Mad cow disease, also known as bovine spongiform encephalopathy (BSE) was first discovered in cattle in the UK in 1986. In 1996, BSE made its way into humans for the first time, setting off panic and fascination with the fatal disease that causes rapid onset dementia. In this episode, Sam and Deboki cover the cause, spread and concern surrounding mad cow and other prion diseases. The Tiny Show &am...

On April 20, 2010, a drilling rig called Deepwater Horizon exploded, capsizing 36 hours later. Eleven workers were killed and, over the next 87 days, more than 100 million gallons of oil spilled into the Gulf of Mexico in what the EPA has called the largest marine oil spill in history. With public distrust of the companies responsible mounting, scientists had to find a way to study the spill and c...

Sam and Deboki will be raffling off Tiny Matters coffee mugs in an upcoming Q&A episode. Entering the raffle is easy! Just send your question(s) to tinymatters@acs.org . Questions can be about pretty much anything — a previous episode, some science thing you're dying to know the answer to, a question about podcasting, or about Deboki's and Sam's past lives as researchers or what helped them ge...

In this episode of Tiny Matters, Sam and Deboki unravel two very different environmental disasters: Hurricane Katrina and this year’s Ohio train derailment. They’ll cover the science underlying those events, the confusion and misinformation that followed them, and how human influence infiltrates all of these disasters, even ones deemed “natural." The Tiny Show & Tell stories are here and here...

A few months ago, we did a bonus Q&A about the HBO series The Last of Us, a show about a pandemic caused by a fungus that turned people into terrifying zombies. After that bonus episode aired, we received emails from people who wanted to learn more about fungi and the fungal infections on the rise, like white nose syndrome in bats and Candida auris in humans. This episode is all about fungal p...

In the mid-20th century, psychedelic research to treat conditions like depression began to take off, yet by 1970 almost all of that work came to a screeching halt. But guess what? It’s back, and access to guided therapy to treat various mental health conditions is becoming a reality. The link to The New York Times article about Roland Griffiths is here . The Tiny Show & Tell stories are here a...

There's a whole lot of information (and misinformation) out there about depression, as well as debate surrounding how it's treated. In this episode, Sam and Deboki unpack this complex mood disorder that impacts over 300 million people across the globe as well as the effectiveness of SSRIs and the work being done to find better drugs. A link to David Hellerstein's new book The Couch, The Clinic and...

The first computer was created in 1945 and came in at double the size of a one-bedroom apartment. Just 50 years later, the architecture of the computer on a chip that measured just 7.44 by 5.29 millimeters in size. And now, computers have gotten smaller and smaller [looks down at Apple Watch]. So how did we go from apartment-sized calculators to the tiny devices we use to look up cat pictures when...

The question of whether or not life exists on other planets is an important and interesting one. But maybe the more intriguing question is, “what if it does?” In this episode of Tiny Matters, Sam and Deboki chat with science writer Jaime Green about what it would mean for life to exist beyond Earth. Her book, “The Possibility of Life: Science, Imagination, and Our Quest for Kinship in the Cosmos,”...

Since the very beginning of the space age, people have been wondering if algae could provide a life support system beyond our planet. From dozens of studies over the last 60 years, we’ve figured out that algae probably can thrive for up to a year in space. But what if we wanted to live permanently on another planet, like Mars? This episode is all about algae: how it shaped early Earth, how we migh...

For millennia, humans have looked to the sea to find medicine. Today, medical treatments that come from the ocean have been clinically approved for pain, cancer, and Alzheimer’s disease, and over a dozen more are in clinical trials. In this episode of Tiny Matters, Sam and Deboki are tackling marine natural products—things like proteins, fats, and other molecules that aquatic organisms produce—tha...

If you’ve been watching HBO’s The Last of Us, you might have some questions about fungus zombies and maybe fungi in general. In this bonus episode, Sam calls up field mycologist Giuliana Furci for a little fungi 101 and to talk fungi fact vs. fiction in the show. We promise there will be no jump scares! Pick up a Tiny Matters mug here ! All Tiny Matters transcripts are available here . See Privacy...

Around 400 million tons of plastic are produced annually, which is the estimated weight of all of humanity! Plastic-covered beaches and litter on the side of the road is gross and depressing, but it turns out that stuff is just the visible tip of the iceberg. Plastic breaks down into tiny, tiny pieces that have now been found in almost every ecosystem on the planet—from the bottom of the ocean to...

In this episode of Tiny Matters, Sam and Deboki go on a detection dog deep dive. These are dogs who can sniff out basically anything, from explosives to invasive pythons to diseases like cancer and COVID-19. How are they trained? Are certain breeds better at recognizing certain odors? And, come to think of it, how do any of us smell things? Links to the Tiny Show & Tell stories here and here ....

Maybe you know Hank Green from Vlogbrothers or CrashCourse. Maybe he taught you something on TikTok. Maybe you’ve read one of his books. Or maybe you know him from about a dozen other things. Hank does a lot, so Sam and Deboki were psyched to get a chance to chat with him. Even more about Hank at https://hankgreen.com/ Episode transcripts at acs.org/tinymatters   See Privacy Policy at https://art1...

For centuries, scientists have looked through microscopes to witness the worlds of tiny creatures and cells that exist all around us. In this episode, Sam and Deboki learn what it takes to hunt down a rare microbe and why it matters for how we understand evolution and the connections between species today. Links to the Tiny Show & Tell stories here and here . Episode transcripts at acs.org/tin...

Over the last year we've talked about the microbiome, the evolution of lactose intolerance, why we've only eradicated one infectious disease, if sugar is actually addictive, vampire science, and so, so much more. There are lots of tiny things out there that have a big impact. So what do YOU want to hear about? What science questions are on your mind? Let us know! tinymatters@acs.org   See Privacy...