Multitude
Tiny Matters
Science shapes every facet of our lives, but so much of its influence is overlooked or buried in the past. Tiny Matters is an award-winning science podcast about the small science of big things. From the microbes behind deadly diseases to the molecules informing our search for extraterrestrial life, hosts and former scientists Sam Jones and Deboki Chakravarti embrace the awe and messiness of science and its significance both today and in the past, asking questions like, "how was IVF invented?," "what do glaciers tell us about Earth’s ancient past?," and "why is smallpox the only human infectio...
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Episodes
The strange science and history of quantum computing and how it could transform chemistry 23.07.2025 26:00
On May 7, 1981, influential physicist Richard Feynman gave a keynote speech at Caltech. Feynman opened his talk by politely rejecting the very notion of a keynote speech, instead saying that he had his own ideas on what to discuss and that everyone should speak on what they please. And for Feynman, this meant proposing a new technology that could simulate physics with computers. That lecture 44 ye...
[BONUS] Squirrel pox and did tin buttons cause the downfall of Napoleon's army?: Tiny Show and Tell Us #27 16.07.2025 13:04
In this episode of Tiny Show and Tell Us, we cover squirrel pox — a disease that hasn’t had a huge impact in the United States but has decimated populations of squirrels in the UK. Then we talk about the story that Napoleon's army lost the Battle of Waterloo because the military uniforms used tin buttons that broke apart in cold temperatures, making it harder for the troops to survive. But is ther...
Making labs safer: A heavy metal poisoning, a deadly protein exposure, and their aftermath 09.07.2025 35:16
In January, 1997, David Nierenberg was a physician at Dartmouth‐Hitchcock Medical Center, specializing in toxicology. Chemist Karen Wetterhahn was placed in his care. When she arrived at the hospital, Karen was slurring her speech and having difficulty balancing and with coordination. What David soon learned was that her symptoms were all due to a few tiny drops of a compound called dimethylmercur...
[BONUS] Fetuses ‘listening’ to different languages and climate change affecting psychiatric meds: Tiny Show and Tell Us #26 02.07.2025 15:55
In this episode of Tiny Show and Tell Us, we talk about how climate change may impact the effectiveness of mental health medications and how heat waves impact mental health more generally. Then we cover how fetal heart rates can change depending on which language they’re hearing while in the womb. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.o...
How NASA scientists are monitoring and predicting wildfires from space 25.06.2025 26:54
Climate change has brought forth extreme fire events, like the Palisade and Eaton fires in Los Angeles, which devastated communities in Altadena and the Pacific Palisades in the beginning of 2025. And it’s becoming harder to not wonder: Is this just the world we live in now? Under the constant threat of catastrophic fires? Fortunately, we have the perfect guests to answer that question. We travele...
[BONUS] The FDA’s ban of Red Dye No. 3 and the surprising science of winter roads: Tiny Show and Tell Us #25 18.06.2025 17:03
In this episode of Tiny Show and Tell Us, we talk about why the FDA recently banned Red Dye No. 3 and how concerned people should be about its use in food. Then we cover icy winter roads and the fascinating science behind clearing them and taking a more sustainable approach that won’t hurt the environment. We need your stories — they're what make these bonus episodes possible! Write in to tinymatt...
How a Mars mission from the 1970s shaped the search for extraterrestrial life today 11.06.2025 35:49
In 1975, NASA launched two spacecraft to Mars. Viking 1 and Viking 2 arrived at their destination less than a year later, each bringing a lander to explore the surface of the planet and an orbiter to survey above. What was supposed to be a 90 day mission ended up lasting until the early 1980s. Those years provided scientists with important data about the Martian landscape, from seismometer reading...
[BONUS] Babies leaving cells behind in mom and rethinking the Big Bang: Tiny Show and Tell Us #24 04.06.2025 17:51
In this episode of Tiny Show and Tell Us, we talk about what dark energy and dark matter are made out of and how knowing more could upend our understanding of the Big Bang. Then we cover microchimeric cells — cells transferred between baby and mom — and how new research in mice shows that fetal cells that took residency in mom from a first pregnancy are replaced by new fetal cells of a second preg...
Ozempic: The science behind this blockbuster drug and its untapped potential 28.05.2025 26:00
In December 2017, the FDA approved a new injectable drug to treat type 2 diabetes called semaglutide, which you likely know by its brand name: Ozempic. A few years later, during the pandemic, Wegovy, a drug with a higher dose of the same active ingredient, was approved specifically for chronic weight management. Soon after, people taking Ozempic started reporting a dramatic, even “life-changing” w...
[BONUS] Marfan syndrome and plant pathogens eating DNA: Tiny Show and Tell Us #23 21.05.2025 12:50
In this episode of Tiny Show and Tell Us, we hear from a listener who has Marfan syndrome and dive into the complexities of the disease. Then we talk about pathogens that eat — or infiltrate! — plant DNA. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org * or fill out this form * with your favorite science fact or science news story for a chanc...
How a little-known vaccine project and decades of HIV research made "Operation Warp Speed" possible 14.05.2025 36:32
Over the last 200 years or so, vaccines have come a long way, for a number of viruses. We’ve made so much progress, in fact, that in 2017 scientists began the early stages of vaccine development for some virus families they believed could pose a future pandemic threat. One of those families was Coronaviridae: coronaviruses. Not many people know that before SARS-CoV-2 started making its way into pe...
[BONUS] Time limits for anesthesia and stunning bioluminescence: Tiny Show and Tell Us #22 07.05.2025 12:35
In this episode of Tiny Show and Tell Us, we break down what limits on anesthesia could mean, both for doctors and patients. Then we hear from a listener who’s on a research trip in Puerto Rico and went kayaking in a bioluminescent bay. What is bioluminescence? And what are the perfect conditions to try to see it? We need your stories — they're what make these bonus episodes possible! Write in to...
The placenta: A disposable organ we can’t live without 30.04.2025 34:57
The placenta is essential for life, but so much of its function is unknown. In this episode, we talk about how this disposable organ’s development within the early weeks of pregnancy shapes so much of what happens months later. We tackle what makes the human placenta so unique, what other animals like reptiles are teaching us about it, and how scientists are turning to evolution and computer model...
[BONUS] An inspiring pharmacist grandma and orcas wearing dead salmon hats: Tiny Show and Tell Us #21 23.04.2025 14:38
In this episode of Tiny Show and Tell Us, we hear from a listener about her incredible grandma who’s a pharmacist in Venezuela (still, at 92 years old!) and has inspired her love of science and current lab work. We then talk about orcas spotted wearing dead salmon as hats, and what this fishy behavior may mean. We need your stories — they're what make these bonus episodes possible! Write in...
How glaciers safeguard Earth’s future and hold clues to our ancient past 16.04.2025 29:16
The reason many of us hear about glaciers has to do with sea level rise — which makes sense! If all of the glaciers on Earth melted, sea levels are predicted to increase by about 230 feet (70 meters), which would flood coastal areas, envelope a number of islands, and seriously impact human infrastructure, including our current water resources. But glaciers do more than safeguard Earth’s future — b...
[BONUS] Evolutionary adaptations to high altitudes and e-cigs vs. dry herb vaporizers: Tiny Show and Tell Us #20 09.04.2025 12:58
In this episode of Tiny Show and Tell Us, we discuss the differences between e-cigarettes (vapes) and far-less-studied dry herb vaporizers. Then we talk about some of the incredible evolutionary adaptations of populations of people living at high altitudes. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org * or fill out this form * with y...
How 18th and 19th century 'race science' still has deadly medical consequences today 02.04.2025 27:55
In the 1700s and early 1800s scientists from Europe and the Americas were studying what they called "race science," a pseudoscientific field of study promoting the idea that humans could be divided into separate and unequal races. Biases stemming from race science have influenced medicine for hundreds of years, and still have deadly consequences today. In this episode of Tiny Matters, we tack...
[BONUS] Crocheted wasp nests and sewage in reefs: Tiny Show and Tell Us #19 26.03.2025 12:51
In this episode of Tiny Show and Tell Us, we discuss if a crocheted wasp nest could actually attract wasps and keep them from invading your property. Then we talk about how sewage is impacting the resilience of coral reefs. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org * or fill out this form * with your favorite science fact or science new...
The rape kit: From controversial 1970s invention to ending the backlog today 19.03.2025 31:17
In the 1970s, the rape kit began as a simple box with some envelopes, a comb, nail clippers, and a few other basic tools. The contents of the kit have evolved somewhat since then, but the technology to analyze samples has evolved astronomically. And, through and through, the rape kit has stood for the idea that every survivor has the right to go to a hospital, get a full forensic exam, and have th...
[BONUS] Double rainbows and mysterious chromosomes: Tiny Show and Tell Us #18 12.03.2025 10:51
In this episode of Tiny Show and Tell Us, we cover the science of rainbows and why double rainbows are always mirror images. Then we talk about mysterious, yet super common, chromosomes called Robertsonian chromosomes that seem to have a significant impact on human health. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org * or fill out this for...
Not just a ‘royal disease’: Hemophilia’s devastating past to recent advances 05.03.2025 33:59
Hemophilia is a rare bleeding disorder caused by a deficiency in clotting factors in the blood, which can cause permanent damage to joints and, in some cases, life threatening bleeding, both externally and internally. Today, people with hemophilia can live generally long, healthy lives, but in previous generations, the future wasn’t so bright. In fact, less than a century ago the life expectancy f...
[BONUS] Fungus farming ants and disappointing orange juice: Tiny Show and Tell Us #17 26.02.2025 15:22
In this episode of Tiny Show and Tell Us, we cover the incredible world of fungus farming ants and how it really needs to be a Pixar movie. Then we talk about what makes fresh squeezed juice taste so much better than the mass produced processed juices you pick up in the grocery store. We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org * or...
How plants shaped our world: Rising oxygen, blocky bones, and other pivotal moments in evolution 19.02.2025 27:53
In the summer of 2011, paleontologist and science writer Riley Black was on a mission. Walking through the Montana desert, she was on the lookout for a Tyrannosaurus rex. But that day, she wasn’t having any luck. Sitting atop a rock, she pulled out a geological hammer, sometimes called a rock pick, to dislodge a little piece and try to discern its composition. What she saw was a leaf, but upon clo...
[BONUS] 'Night soil' recycling and could viruses be the new antibiotics?: Tiny Show and Tell Us #16 12.02.2025 16:01
In this episode of Tiny Show and Tell Us, we consider if bacteriophages could become our biggest allies in the fight against antibiotic resistance. Then we cover the historical role of "night soil men" and how some sewage treatment systems today are setting the standard for sustainable management of human excrement while also making sure we don't get sick. We need your stories — they're what make...
Can evolution go backwards? 05.02.2025 30:23
In 1893, Belgian paleontologist Louis Dollo suggested that evolution can’t go backwards in the exact same way that it proceeded. This became known as “Dollo’s Law,” and came under a lot of scrutiny. But, more recently, Dollo’s Law was co-opted into the idea that traits, once they gain a certain amount of complexity, can’t return to a simpler state. In this episode of Tiny Matters, we explore two e...
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