This Week in Virology

Vincent and Rich update the current situation with COVID-19 and SARS-CoV-2, including fatality ratios, virus spreading outside of China, immunity to infection, vaccines, antivirals and much more. Hosts:  Vincent Racaniello and Rich Condit Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode WHO CoV sitreps How to Prepare for the Coronavirus...

The TWiV team returns this week to SARS-CoV-2019 coverage to review the latest epi curves, the fatality rate, furin cleavage site and receptor binding domain in the spike glycoprotein, related CoV recovered from pangolins, evidence that the virus did not escape from a laboratory, and many more questions sent in by listeners. Hosts:  Vincent Racaniello , Dickson Despommier , Rich Condit , and Kathy...

Vincent and Rich return to the University of Texas Medical Branch at Galveston to speak with Dennis Bente, Shannan Rossi, Nikos Vasilakis, and Scott Weaver about their work on viruses transmitted by mosquitoes and ticks. Hosts:  Vincent Racaniello and Rich Condit Guests: Dennis Bente , Shannan Rossi , Nikos Vasilakis , and Scott Weaver Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email B...

In this week's coverage of the coronavirus epidemic, the TWiV team discusses the fatality rate, China's initial reaction to the outbreak, conspiracy theories, how long the virus remains infectious on surfaces, and evidence for virus in the intestinal tract. Hosts:  Vincent Racaniello , Dickson Despommier , Alan Dove , Rich Condit , and Brianne Download  TWiV 586 (72 MB .mp3, 119 min) Subscribe (fr...

The TWiVerers continue their coverage of the new coronavirus outbreak in China, as the number of cases increase dramatically and the virus begins person-to-person transmission in other countries. Hosts:  Vincent Racaniello , Dickson Despommier , Alan Dove , Rich Condit , Kathy Spindler , and Brianne Barker Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Link...

Coronavirus expert Ralph Baric joins TWiV to explain the virology and epidemiology of the recent zoonotic outbreak spreading across China and overseas. Hosts:  Vincent Racaniello , Dickson Despommier , Alan Dove , Rich Condit , Kathy Spindler Guest: Ralph Baric Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode ASV 2020 WHO coronavirus si...

Vincent and Rich travel to Galveston National Laboratory to speak with Jim LeDuc, Tom Ksiazek, and Bob Tesch about their long careers as virus hunters. Hosts:  Vincent Racaniello and Rich Condit Guests: Jim LeDuc , Tom Ksiazek , and Bob Tesh Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Intro music is by  Ronald Jenkees . Send your virology questions and c...

TWiV provides updates on the new coronavirus causing respiratory disease in China, the current influenza season, and the epidemic of African swine fever, including determination of the three-dimensional structure of the virus particle. Hosts:  Vincent Racaniello , Dickson Despommier , Rich Condit , Kathy Spindler , and Brianne Barker Download  TWiV 582 (71 MB .mp3, 118 min) Subscribe (free):  iTun...

For the first TWiV of 2020 we reveal that microbiome depletion with antibiotics alters the immune response to influenza vaccine, and how successive blood meals facilitate virus dissemination in mosquitoes and transmission potential. Hosts:  Vincent Racaniello , Dickson Despommier , Alan Dove , Kathy Spindler , and Brianne Barker Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email Become a...

From the University of Texas at Austin, Vincent and Rich speak with Chris Sullivan about his work on miRNAs encoded in the genomes of polyomaviruses and papillomaviruses, and how an RNA triphosphatase restricts hepatitis C virus replication. Hosts:  Vincent Racaniello and Rich Condit Guest: Chris Sullivan Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links...

Vincent speaks with virologists at the University of Nevada at Reno about their careers and their work on herpesviruses, arboviruses, and the development of diagnostics for infectious diseases. Host:  Vincent Racaniello Guests: Dave AuCoin , Cyprian Rossetto , Claudia Rückert , and Subhash Verma Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this...

Vincent speaks with members of Prometheus, a team of academic and industrial scientists assembled to develop antibody-based therapeutics against infections caused by tick-borne Crimean-Congo hemorrhagic fever virus and rodent-borne hantaviruses, for which no approved vaccines or specific drugs are available. Host:  Vincent Racaniello Guests: Kartik Chandran , Zachary Bornholdt , Steven Bradfute ,...

Vincent speaks with Félix Rey about his career and his work on solving structures of a variety of viruses and the insights learned about viral membrane fusion and antibody-mediated neutralization. Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode Unité de Virologie Structurale Tick-borne encephalitis glycoprotein structure (Nature) HCV R...

From the 22nd meeting of the European Society for Clinical Virology in Copenhagen, Vincent speaks with Thea, Heli, Kim, Caroline and Irma about big data and its increasing use in virology diagnostics, epidemiology, and public health. Host:  Vincent Racaniello Guests: Thea Kølsen Fischer , Kim Benschop , Caroline Brown , Heli Harvala , and Irma Salimovic-Besic Subscribe (free):  iTunes ,  Google Po...

From the Fourth Symposium on Giant Virus Biology in Germany, Vincent, Rich, and Nels speak with Assaf, Stephen, and Alexandra about their careers and their work on giant viruses that infect ocean hosts:  Emiliana huxleyi , Aureococcus anophagefferans , and a choanoflagellate. Hosts:  Vincent Racaniello , Rich Condit , and Nels Elde Guests: Assaf Vardi , Stephen Wilhelm , and Alexandra Worden Subsc...

From Georgia State, Vincent speaks with economics professor Paula Stephan about the ways science is supported in the US, how universities offload risks, the absence of risk-taking, and much more. Hosts:  Vincent Racaniello Guest: Paula Stephan Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode How Economics Shapes Science Coalition for Ne...

William Summers joins the TWiV team to discuss some virology history, including the ever-changing concept of 'virus' and the contribution of phage research to the study of animal viruses. Hosts:  Vincent Racaniello , Dickson Despommier , Alan Dove , and Rich Condit Guest: William Summers Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode...

Amy joins the TWiV team to review evidence that enterovirus D68 is an etiologic agent of childhood paralysis, and her finding that the ability of the virus to infect cells of the nervous system is not a recently acquired property. Hosts:  Vincent Racaniello , Dickson Despommier , Rich Condit , and Kathy Spindler Guest: Amy Rosenfeld Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email Beco...

The League of Extraordinary Virologists celebrate the eradication of wild poliovirus type 3, and consider the effectiveness of an influenza vaccine produced in insect cells, and how small RNAs are protecting the Koala germline from retroviral invasion. Hosts:  Vincent Racaniello , Dickson Despommier , Alan Dove , Kathy Spindler , and Brianne Barker Subscribe (free):  iTunes ,  Google Podcasts ,  R...

At Aarhus University in Denmark, Vincent speaks with Trine Mogensen, Søren Paludan, Ole Søgaard, and Madalina Carter-Timofte about their careers and their work on sensing herpesviral DNA, immunodeficiencies that predispose to severe viral infections, and the path to a cure for HIV/AIDS. Hosts:  Vincent Racaniello Guests: Trine Mogensen , Søren Paludan , Ole Søgaard , and Madalina Carter-Timofte Su...

The TWiV pro-vaxxers reveal viruses that infect endangered wild salmon, and how iron in host serum modulates dengue virus acquisition by mosquitoes. Hosts:  Vincent Racaniello , Dickson Despommier , Alan Dove , and Brianne Barker Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode New viruses that infect endangered wild salmon (eLife) Host...

 In the second episode from the Karolinska Institute in Stockholm, Vincent speaks with Jan Albert, Petter Brodin, and Anna Smed-Sörensen about their work on enterovirus D68, systems immunology, and human pulmonary viral infection and inflammation. Hosts:  Vincent Racaniello Guests: Jan Albert , Petter Brodin , and Anna Smed-Sörensen Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email Beco...

The TWiV team covers outbreaks of eastern equine encephalitis virus in the US and poliovirus in the Philippines, and explain how a chemokine induced by HIV-1 infection helps release more virus particles from cells. Hosts:  Vincent Racaniello , Dickson Despommier , Alan Dove , Rich Condit , Kathy Spindler , and Brianne Barker Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email Become a  pa...

The TWiV team reveals the protein corona that surrounds virus particles and influences infectivity and amyloid aggregation, and a proofreading-impaired herpesvirus that produces quasispecies-like populations. Hosts:  Vincent Racaniello , Alan Dove , and Rich Condit Guest: Kiki Warren Subscribe (free):  iTunes ,  Google Podcasts ,  RSS ,  email Become a  patron  of TWiV! Links for this episode Huma...

From the Karolinska Institute in Stockholm, Vincent speaks with Niklas Björkström, Ali Mirazimi, and Matti Sällberg about their work on the impact of chronic hepatitis C virus infection on NK cells, Crimean-Congo hemorrhagic fever virus vaccines, and immunotherapy to block entry of hepatitis B and D viruses. Hosts:  Vincent Racaniello Guests: Niklas Björkström , Ali Mirazimi , and Matti Sällberg S...