Jason Calacanis

This Week in Startups

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

Author

Jason Calacanis

Category

Technology

Podcast website

thisweekinstartups.com

Latest episode

Jul 10, 2026

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Episodes

Is OpenAI Really Worth $300B? ElevenLabs' Series C & YC's Funding Focus | E2079 01.02.2025

Today's show: The AI revolution is about to hit your household—Jason and Alex break down how general-purpose robots, AI-powered chicken coops, and voice clones are redefining daily life and work. They dig into OpenAI's sky-high valuation, the surprising rise of DeepSeek's R1 model, and why the AI cost curve is dropping at an insane pace. Plus, the latest on AI hardware, antitrust battles, and why...

Boom Supersonic's Milestones, OpenAI Ethics, and Startup Tools | E2078 29.01.2025

This Week in Startups is brought to you by… Vanta. Get $1000 off your SOC 2 at https://www.vanta.com/twist Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://northwestregisteredagent.com/twist ⁠ today. Scalable Path. Get 20% off your first month at https://www.scalablepath.com/twist Today's show: Jason and Alex cover Jason...

DeepSeek Rattles Markets + SailPoint's Going Public… again? | E2077 27.01.2025

Today's show: A $6M open-source AI model from China, DeepSeek, sends shockwaves through Wall Street, wiping billions off NVIDIA's market cap and forcing a rethink on AI infrastructure spending. We explore the 25% surge in startup shutdowns, the lessons from leaner teams, and why some companies just couldn't make the runway. Plus, SailPoint returns to the public markets saddled with $1.6B in debt—w...

Twilio Bets Small, DeepSeek Scares & the GameOn Fraud | E2076 24.01.2025

This Week in Startups is brought to you by… Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www. Squarespace.com/TWIST Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up. Today's show: Jason...

Created By Humans | Sila's Battery Evolution | E2075 23.01.2025

This Week in Startups is brought to you by… Gusto. Get three months free when you run your first payroll at http://gusto.com/twist *Gusto pricing shown in ad is based on pricing prior to March 2025 Netsuite. Download the CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist Atlassian. Head to Atlassian.com/Startups/TWiST to see if you qualify for 50 free seats for 12 mo...

Trump, Memecoins, and What to Expect from the New Administration | E2074 21.01.2025

Today's show: Jason and Alex explore America's fascination with billionaires and self-made figures, touching on recent events in Washington, DC, and the tech industry's political influence. They discuss Gen X's rising political power, tech CEOs' prominence at inaugurations, and critique Democrats' tech policies. The conversation covers economic factors in elections, like inflation and abortion rig...

TikTok Ban, Data Centers in Space… and What's a Vector? | E2073 17.01.2025

Today's show: Alex sits down with two CEOs from companies freshly added to the TWIST500. We get a masterclass from Bob van Luijt of Weaviate, on vector databases helping AI and LLMs do what they do. An then Philip Johnston from Lumen Orbit explains his vision of building data centers in space! * Timestamps: (0:00) Alex kicks off the show. (0:58) Supreme Court ruling on TikTok and key market number...

What's Going On With Google Gemini Deep Research? | E2072 16.01.2025

This Week in Startups is brought to you by… PrizePicks. TWiST listeners, download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to: https://prizepicks.onelink.me/LME0/TWIST PrizePicks - Run your game. Coda. TWiST listeners get 6 months at https://www. Coda.io/twist Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign...

Profound, Resistant AI & OpenAI's Economic Pitch | E2071 14.01.2025

Today's show: Alex covers Mark Zuckerberg's Joe Rogan interview, OpenAI's economic pitch and the pending IPO of India's Groww. Our guests include two companies freshly added to the TWIST500: James Cadwallader from Profound and Martin Rehak from Resistant AI. * Timestamps: (0:00) Alex kicks off the show! (2:51) A look at key moments from this week's Mark Zuckerberg interview on Rogan. (8:08) James...

The LA Fire's Cost and the U.S. Jobs Report | E2070 10.01.2025

This Week in Startups is brought to you by… Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit ⁠ https://www.northwestregisteredagent.com/twist t today. Atlassian. Head to https://www.atlassian.com/Startups/TWiST to see if you qualify for 50 free seats for 12 months. LinkedIn Ads. To redeem a $100 LinkedIn ad credit and launch you...

Meta's Moderation and Nvidia's Domination | E2069 08.01.2025

This Week in Startups is brought to you by… Gusto. Get three months free when you run your first payroll at http://gusto.com/twist *Gusto pricing shown in ad is based on pricing prior to March 2025 Oracle. TWiST listeners can try OCI and save up to 50% on your cloud bill at https://w⁠⁠⁠⁠ww.oracle.com/twist⁠⁠⁠ Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a web...

Twist News: Fusion, Rural Investment, and Applied AI | E2068 06.01.2025

This Week in Startups is brought to you by… PrizePicks. TWiST listeners, download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to: https://prizepicks.onelink.me/LME0/TWIST PrizePicks - Run your game. Lemon.io . TWiST listeners get 15% off your first 4 weeks of developer time at https://Lemon.io/twist Vanta. TWiST listeners automate your SOC2 and get...

Venture Concentration, High-Skill Immigration, And Who Should Buy Lyft? | E2067 04.01.2025

This Week in Startups is brought to you by… Paddle. Wherever you want to take your business, go there with Paddle. Go to paddle.com/twist to get started with your exclusive listener fee-free period. Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up now at fitbod. me/TWIST . LinkedIn Ads. Get a $100 LinkedIn ad credit: http://www.linkedin.com/thisweekinstartu...

2024 TWISTY Awards | E2066 31.12.2024

This Week in Startups is brought to you by… Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www. Squarespace.com/TWIST OpenPhone. TWiST listeners can get 20% off your first 6 months at https://openphone.com/twist Notion: TWiST listeners can try it for free at https://notion.com/twist Todays show: The 2024 TWISTY Awards are here! Jaso...

Palantir's Valuation, VC's Go To Washington and Much More | E2065 24.12.2024

This Week in Startups is brought to you by… Oracle. TWiST listeners can try OCI and save up to 50% on your cloud bill at ⁠⁠https://w⁠⁠⁠⁠ww.oracle.com/twist⁠⁠⁠ DevSquad. TWIST listeners can get 10% off at http://devsquad.com/twist Ramp. TWiST listeners, get $250 when you join Ramp today at https://www.ramp.com/twist Todays show: Jason & Alex discuss Palantir's valuation, possible opt-in empire buil...

Codeium's Vision for AI-Driven Development with Varun Mohan | E2064 20.12.2024

This Week in Startups is brought to you by… Squarespace. Turn your idea into a new website! Go to https://www. Squarespace.com/TWIST for a free trial. When you're ready to launch, use offer code TWIST to save 10% off your first purchase of a website or domain. LinkedIn Ads. To redeem a $100 LinkedIn ad credit and launch your first campaign, go to http://www.linkedin.com/thisweekinstartups PrizePic...

Databricks' Record Raise, TikTok goes to the Supreme Court, and all about the Grammarly-Coda Deal | E2063 19.12.2024

This Week in Startups is brought to you by… Coda. Coda empowers your startup by bringing words, tables, and teams together. Strategize, plan, and track goals effectively with all your valuable data in one place. Go to https://www.coda.io/twist to get started for FREE and get 6 free months of the Team plan. Lemon.io - Hire pre-vetted remote developers, get 15% off your first 4 weeks of developer ti...

Sora Disappoints, ChatGPT Pro Tested, Inference Time Reasoning & More with Sunny Madra | E2062 18.12.2024

Timestamps: (0:00) Jason and Sunny kick off the show (1:26) Discussing Groq's recent developments and Middle East tech inspiration (3:51) Global business challenges and Jason's 2025 announcements (7:53) Gemini app demo and ChatGPT 4 comparison (9:57) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist (11:24) Evaluating ChatGPT 4.0 Pro limitations and robo-taxi fl...

Silicon Valley Clones and Jersey Drones: Decoding the Signals with Nicole Wischoff | E2061 17.12.2024

This Week in Startups is brought to you by… Ramp. The corporate card and spend management software designed to help you save time and money. Get $250 when you join Ramp today at https://www.ramp.com/twist . DevSquad. Most dev agencies only offer developers. Why? Because product management is hard. Get an entire product team for the cost of one US developer plus 10% off at http://devsquad.com/twist...

Cyera's Hypergrowth, Cake's Cap Table Push, and ServiceTitan's Stellar IPO | E2060 13.12.2024

This Week in Startups is brought to you by… LinkedIn Jobs. A business is only as strong as its people, and every hire matters. Go to https://www.linkedin.com/twist to post your first job for free. Terms and conditions apply. Washington Post. Stay informed with trusted journalism from The Washington Post. Right now, TWiST listeners can subscribe for just 50 cents per week for your first year at htt...

The Top 6 Startup Finance FAQ's | Startup Finance Basics w/ Kruze's Scott Orn 12.12.2024

Todays show: In the latest edition of Startup Finance Basics, Jason sits down with Scott Orn from Kruze Consulting to answer the six most important founder/startup questions around finance, accounting, and taxes. * Timestamps: (0:00) Kruze COO, Scott Orn, joins Jason to dive into Finance Basics FAQs. (1:05) How can I avoid paying payroll tax as a startup founder? (6:54) How do you shut down a star...

Negative Venture Returns, GM Kneecaps Cruise, and Finix joins the TWiST500 | E2059 12.12.2024

This Week in Startups is brought to you by… OpenPhone. Create business phone numbers for you and your team that work through an app on your smartphone or desktop. TWiST listeners can get an extra 20% off any plan for your first 6 months at https://www.openphone.com/twist⁠ Vanta. Compliance and security shouldn't be a deal-breaker for startups to win new business. Vanta makes it easy for companies...

Drones, Deepfakes, and Disruptors with Lon Harris, Remento and Cuby | E2058 11.12.2024

This Week in Startups is brought to you by… Squarespace. Turn your idea into a new website! Go to https://www. Squarespace.com/TWIST for a free trial. When you're ready to launch, use offer code TWIST to save 10% off your first purchase of a website or domain. Lemon.io - Hire pre-vetted remote developers, get 15% off your first 4 weeks of developer time at https://Lemon.io/twist Oracle - Oracle Cl...

TWiST News: Bitcoin's Future, Reddit Answers, SEC Shifts, and more! | E2057 10.12.2024

This Week in Startups is brought to you by… Ramp. The corporate card and spend management software designed to help you save time and money. Get $250 when you join Ramp today at https://www.ramp.com/twist Zendesk. The best customer experiences are built with Zendesk. Qualifying startups can join their Startup program and get Zendesk products free, for six months! Visit http://www.zendesk.com/twist...

Ghost Engineers, Measuring Productivity, & Memecoin Scams | E2056 07.12.2024

Todays show: In this episode, we discuss Hailey Welch and the viral Hawk coin, then discuss David Sachs' new White House role and recent job data's economic impact. We address the United Healthcare CEO's murder, debate cancel culture, and a viral tweet on software engineers' habits. Deedy Das offers insights on tech inefficiencies and the shift to in-person work. Coffeezilla joins to explore crypt...

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