This Week in Parasitism

The TWiP team solves the case of the Woman Who Vomited Up a Worm, and discuss how malaria transmission intensity can modify the effectiveness of the RTS, S/AS01 vaccine in Africa. Hosts:  Vincent Racaniello , Dickson Despommier ,  Daniel Griffin , and Christina Naula Subscribe (free):  Apple Podcasts , Google Podcasts ,  RSS ,  email Links for this episode Malaria intensity modifies vaccine effect...

Claire joins the TWiP team to discuss her training and experience as an infectious disease physician, and her transition to science communication, then we solve the case of the Honduran Male with Seizures. Hosts:  Vincent Racaniello , Dickson Despommier ,  Daniel Griffin , and Christina Naula Guest: Claire Panosian Subscribe (free):  Apple Podcasts , Google Podcasts ,  RSS ,  email Links for this...

The TWiP team solves the case of the Ghanian Women With Leg Swelling, and relate how Anopheline mosquitoes are protected against parasite infection by tryptophan catabolism in gut microbiota. Hosts:  Vincent Racaniello , Dickson Despommier ,  Daniel Griffin , and Christina Naula Subscribe (free):  Apple Podcasts , Google Podcasts ,  RSS ,  email Links for this episode Bacteria protect mosquitoes f...

The TWiP team solves the case of the Pregnant Ghanian Living Near a River, and reveal emodepside, a drug for treatment of onchocerciasis. Hosts:  Vincent Racaniello , Dickson Despommier ,  Daniel Griffin , and Christina Naula Download  TWiP #205 (56 MB .mp3, 93 minutes) Subscribe (free):  Apple Podcasts , Google Podcasts ,  RSS ,  email Links for this episode Emodepside for onchocerciasis (PlOS NT...

The TWiP team solves the case Two Ghanians Near A Fast-Flowing River, and discuss a promising new drug for treatment of African trypanosomiasis. Hosts:  Vincent Racaniello , Dickson Despommier ,  Daniel Griffin , and Christina Naula Subscribe (free):  Apple Podcasts , Google Podcasts ,  RSS ,  email Links for this episode Oral fexinidazole for African trypanosomiasis (Lancet) Hero: Madeline Albrig...

The TWiP team solves the case of the Shopkeeper with Thirst, Rash, and low Blood Oxygen, then review a study on the effect on survival to adulthood in Tanzania of mosquito net use in early childhood. Hosts:  Vincent Racaniello , Dickson Despommier ,  Daniel Griffin , and Christina Naula Subscribe (free):  Apple Podcasts , Google Podcasts ,  RSS ,  email Links for this episode Mosquito net use in T...

Sara from the Febrile Podcast joins the TWiP team at The Incubator to solve the case of the Man With an Egg Laden Colonic Mass, and Daniel presents a new puzzle for us to solve. Hosts:  Vincent Racaniello , Dickson Despommier ,  Daniel Griffin , and Christina Naula Guest: Sara Deng Click arrow to play Download  TWiP #201 (72 MB .mp3, 60 minutes) Subscribe (free):  iTunes , Google Podcasts ,  RSS ,...

The TWiP team solves the case of the Man with a Cat and Ring Enhancing Lesions, and discuss domestic mammals as reservoirs for Leishmania donovani on the Indian subcontinent. Hosts:  Vincent Racaniello , Dickson Despommier ,  Daniel Griffin , and Christina Naula Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  email Links for this episode Reservoirs for Leishmania (Transboundary Emerg Dis) Su...

The TWiP team solves the case of the Gentleman from New York with Intestinal Issues, and review a 20 year study of butterflies, their associated parasitoid wasp and Wolbachia introduced into an island community. Hosts:  Vincent Racaniello , Dickson Despommier ,  Daniel Griffin , and Christina Naula Download  TWiP #200 (41 MB .mp3, 68 minutes) Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  e...

The TWiP team solves the case of the Traveler to Tanzania with a Purple Lesion, and discuss Mosquirix, the first vaccine approved for Plasmodium parasites. Hosts:  Vincent Racaniello , Dickson Despommier ,  Daniel Griffin , and Christina Naula Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  email Links for this episode PWB on Facebook , Instagram , Twitter Historic malaria vaccine (Nature) E...

The TWiP quadfecta solves the case of the Traveler With Watery Diarrhea, and reveals that a heat-shock response regulated by a transcription factor protects human malaria parasites from the high temperatures of fever. Hosts:  Vincent Racaniello , Dickson Despommier ,  Daniel Griffin , and Christina Naula Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  email Links for this episode PWB on Face...

TWiP solves the case of the Adventurous Eater with Areas of Swelling, and discusses an experimental Trypanosoma vivax vaccine comprising an invariant flagellum antigen. Hosts:  Vincent Racaniello , Dickson Despommier ,  Daniel Griffin , and Christina Naula Download  TWiP #197 (39 MB .mp3, 64 minutes) Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  email Links for this episode PWB on Facebook...

TWiP solves the case of the Homeless Man With Skin Issues, and discusses an experimental mRNA based malaria vaccine. Hosts:  Vincent Racaniello and  Daniel Griffin Download  TWiP #196 (49 MB .mp3, 81 minutes) Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  email Links for this episode PWB on Facebook , Instagram , Twitter Entomophagy ( TWiP 131 ) Malaria mRNA vaccine (NPJ vaccines) Letters r...

Christina returns to the TWiP trifecta to solve the case of the Beachgoer with Red Lines on Her foot, and an experimental malaria vaccine based on the junctional region of the circumsporozoite protein displayed on a virus-like particle. Hosts:  Vincent Racaniello , Dickson Despommier , and  Daniel Griffin Guest: Christina Naula Download  TWiP #195 (46 MB .mp3, 76 minutes) Subscribe (free):  iTunes...

TWiP solves the case of the Long Island Man with Unilateral Eye Pain, followed by a discussion of how enteric helminth coinfection enhances host susceptibility to West Nile virus by a tuft cell-IL-4 receptor signaling axis. Hosts:  Vincent Racaniello , Dickson Despommier , and  Daniel Griffin Guest: Christina Naula Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  email Links for this episode...

Audun returns to help solve the case of the Ecuadorean Gentleman Treated for COVID-19, followed by a discussion of the interaction of Blastocystis with the intestinal microbiota and the immune system, and of course a new clinical case from Daniel. Hosts:  Vincent Racaniello , Dickson Despommier , and  Daniel Griffin Guest: Audun Lier Download  TWiP #192 (46 MB .mp3, 76 minutes) Subscribe (free): ...

The TWiPers solve the case of the Teenager in Malawi with Red Urine, then Audun joins to present our clinical case for this episode. Hosts:  Vincent Racaniello , Dickson Despommier , and  Daniel Griffin Guest: Audun Lier Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  email Links for this episode PWB on Facebook , Instagram , Twitter Hero: George B. Craig Letters read on TWiP 192 Become a  p...

The TWiPers solve the case of the Rural Man from North Carolina with Blurred Vision, and discuss the results of single-cell RNA sequencing of Schistosoma mansoni. Hosts:  Vincent Racaniello , Dickson Despommier , and  Daniel Griffin Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  email Links for this episode PWB on Facebook , Instagram , Twitter RNAseq atlas of S. mansoni (Science) Hero: Kat...

Christina from Glasgow returns to help the TWiPlets solve the case of the Ghanian Woman with Abdominal Mass, followed by discussion of the impact of COVID-19 on malaria morbidity and mortality in Africa. Hosts:  Vincent Racaniello , Dickson Despommier , and  Daniel Griffin Guest: Christina Naula Download  TWiP #190 (57 MB .mp3, 94 minutes) Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  emai...

Christina from Glasgow joins the TWiPlets to solve the case of the Elderly Gentlemen with Full Body Rash, and to present a new clinical case for listeners to solve. Hosts:  Vincent Racaniello , Dickson Despommier , and  Daniel Griffin Guest: Christina Naula Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  email Links for this episode PWB on Facebook , Instagram , Twitter Support MicrobeTV thr...

Dickson, Daniel and Vincent solve the case of the Baby with Hydrocephalus, and present a new clinical case for listeners to solve. Hosts:  Vincent Racaniello , Dickson Despommier , and  Daniel Griffin Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  email Links for this episode PWB on Facebook , Instagram , Twitter Letters read on TWiP 188 Become a  patron  of TWiP Case Study for TWiP 188 Man...

Dickson, Daniel and Vincent solve the case of the Middle Aged Woman with Loss of Vision in One Eye, and discuss the role of heme oxygenase in the various protozoan infections. Hosts:  Vincent Racaniello , Dickson Despommier , and  Daniel Griffin Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  email Links for this episode Heme oxygenase-1 in protozoan infections (PLoS Path) Support Floating D...

Dickson, Daniel and Vincent solve the case of the Elder Gardener Feeling Poorly, and discuss the three-dimensional ultrastructure of Plasmodium falciparum during cytokinesis. Hosts:  Vincent Racaniello , Dickson Despommier , and  Daniel Griffin Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  email Links for this episode Three-dimensional structure of malaria parasite (PLoS Path) Support Floa...

Dickson, Daniel and Vincent solve the case of the Wife of a Guy with Cyclospora Diarrhea, and discuss the discovery of an intrinsic oscillator that drives the bloodstream stage cycle of the malaria parasite. Hosts:  Vincent Racaniello , Dickson Despommier , and  Daniel Griffin Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  email Links for this episode Intrinsic oscillator in malaria parasit...

Dickson, Daniel and Vincent solve the case of the Safari Goer With Watery Diarrhea, and explain how a microsporidian endosymbiont of Anopheles mosquitoes might impair the transmission of malaria. Hosts:  Vincent Racaniello , Dickson Despommier , and  Daniel Griffin Subscribe (free):  iTunes , Google Podcasts ,  RSS ,  email Links for this episode Contribute to Parasites Without Borders Microsporid...