Vincent Racaniello

This Week in Parasitism

Science EN ↓ 283 episodes

TWiP is a monthly netcast about eukaryotic parasites. Vincent Racaniello and Dickson Despommier, science Professors from Columbia University, deconstruct parasites, how they cause illness, and how you can prevent infections.

Author

Vincent Racaniello

Category

Science

Podcast website

microbe.tv

Latest episode

Jul 7, 2026

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Episodes

TWiP 258: The deeper, the rounder 13.05.2025

TWiP describes how a gut commensal protozoan influences respiratory disease outcomes by shaping pulmonary immunity, and body shape variation in lice that parasitize diving hosts. Hosts:  Vincent Racaniello ,  Daniel Griffin , and Christina Naula Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Gut commensal  shapes pulmo...

TWiP 257: Malaya and Malaysia 20.04.2025

TWiP solves the case of the man in the Malaysian city of Kucheng who presents with left arm swelling, and presents a new case for you to decipher. Hosts:  Vincent Racaniello ,  Daniel Griffin , and Christina Naula Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Letters read  on TWiP 257 New Case We are still in Kuching,...

TWiP 256: Amazing antimalarial drug resistance 04.04.2025

TWiP explains a study that carries out selection of  Plasmodium falciparum in the presence of inhibitors to identify determinants of drug resistance, and a paleoparasitological analysis of a 5th–16th c. CE latrine. Hosts:  Vincent Racaniello ,  Daniel Griffin , and Christina Naula Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discor...

TWiP 255: Katayama fever 22.03.2025

Michelle Labrunda joins TWiP to solve the case of the Georgian in Guinea with fever and dry cough, and describe a new case for you to solve. Hosts:  Vincent Racaniello ,  Daniel Griffin , and Christina Naula Guest: Michelle Labrunda Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Letters read  on TWiP 255 New Case A man...

TWiP 254: Our hero Dickson 09.03.2025

TWiP explains a study which finds that tissue spaces are reservoirs of antigenic diversity for Trypanosoma brucei, then remembers our departed colleague Dickson Despommier. Hosts:  Vincent Racaniello ,  Daniel Griffin , and Christina Naula Click arrow to play Download TWiP #254 (88 MB .mp3, 61 minutes) Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join...

TWiP 253: Sub-Saharan somnolence 22.02.2025

TWiP solves the case of the man with somnolence and something extra-erythrocytic, and presents a new puzzle for you to solve. Hosts:  Vincent Racaniello ,  Daniel Griffin , and Christina Naula Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Letters read  on TWiP 253 New Case 26-year-old female with no past medical histo...

TWiP 252: For malaria vaccine, mosquito is the needle 10.02.2025

TWiP discusses a study of the safety and immunogenicity of a late liver-stage attenuated malaria parasite delivered by mosquito bite. Hosts:  Vincent Racaniello ,  Daniel Griffin , and Christina Naula Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Live attenuated  malaria vaccine  (NEJM) Plasmodium  metabolism  during...

TWiP 251: Case of the facial ulcer 17.01.2025

TWiP solves the case of the woman who went to Belize and notices a lesion on her face, and presents a new clinical case for you to solve. Hosts:  Vincent Racaniello ,  Daniel Griffin , and Christina Naula Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Letters read  on TWiP 251 New Case Recent case, Arusha hospital, 180...

TWiP 250: Gut bacteria help Trichinella suppress colitis 03.01.2025

TWiP reviews a study showing that the gut microbiota is essential for suppression of colitis by  Trichinella spiralis . Hosts:  Vincent Racaniello ,  Daniel Griffin , and Christina Naula Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Gut bacteria and  Trichinella   suppression of colitis  (PLoS NTD) Become a  patron  o...

TWiP 249: A virus and a parasite 20.12.2024

TWiP solves the case of the middle-aged man with eosinophilia and a history of sexual activity with paid sex workers in Okinawa, and presents a new case for you to solve. Hosts:  Vincent Racaniello ,  Daniel Griffin , and Christina Naula Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Letters read  on TWiP 249 New Case...

TWiP 248: Toxoplasma reduces Alzheimer's disease 06.12.2024

TWiP reviews the observation that infection of Azlheimer's disease mice with  Toxoplasma gondii  reduces brain amyloid density globally and regionally. Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Daniel Griffin , and Christina Naula Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Toxoplasma   reduces amyloid  in...

TWiP 247: Manhattan mystery malady 18.11.2024

TWiP solves the case of the Manhattan man with pain on urination or ejaculation, and presents a new case for you to solve. Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Daniel Griffin , and Christina Naula Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Hero:  Charles Louis Alphonse Laveran Letters read  on TWiP 2...

TWiP 246: Everything spiral: a worm in a hurry 01.11.2024

TWiP taps into Dickson's knowledge of  Trichinella to discuss an outbreak in humans who consumed rare bear meat, and the impact of globalization and climate change on the epidemiology of the species. Hosts:  Vincent Racaniello ,  Dickson Despommier , and  Daniel Griffin Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Ou...

TWiP 245: Flying purple people eater with Ben LaBrot 18.10.2024

Founder of Floating Doctors Ben LaBrot joins TWiP to solve the case of the 1 year old in northeastern Panama with a fatal leg infection, followed by a discussion of the history and mission of Floating Doctors. Hosts:  Vincent Racaniello , Daniel Griffin , and  Christina Naula Guest:  Ben LaBrot Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the Mic...

TWiP 244: Engineering Toxoplasma 05.10.2024

Lilach Sheiner joins TWiP to talk about her career and her work on engineering  Toxoplasma gondii secretion systems for intracellular delivery of multiple large therapeutic proteins to neurons. Hosts:  Vincent Racaniello ,  Dickson Despommier , and  Christina Naula Guest:  Lilach Sheiner Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV ...

TWiP 243: Don't blame it on Mexico 20.09.2024

TWiP solves the case of the Woman with White Worms, and submits a new case involving a 1 year old in northeastern Panama with a fatal leg infection. Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Daniel Griffin , and  Christina Naula Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Enterobius, the pinworm ( TWiP 19...

TWiP 242: Worms impair COVID vaccines 06.09.2024

TWiP reviews a study showing that intestinal helminth infection impairs vaccine-induced T cell responses through an IL-10 pathway, which compromised protection against antigenically drifted SARS-CoV-2 variants. Hosts:  Vincent Racaniello ,  Daniel Griffin  and  Christina Naula Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord se...

TWiP 241: There once was a patient from China 19.08.2024
TWiP 240: A daily history of malaria with Sean Murphy 02.08.2024

Sean Murphy joins TWiP to discuss his career and the work of his laboratory to assess the daily natural history of asymptomatic  Plasmodium infections in adults and older children in Katakwi, Uganda. Hosts:  Vincent Racaniello ,  Dickson Despommier  and  Christina Naula Guest:  Sean Murphy Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeT...

TWiP 239: Cryptosporidiosis from NYC tap water in an AIDS patient 19.07.2024

TWiP solves the case of the AIDS patient who developed fever and watery diarrhea after drinking NYC tap water, and present a new case for your sleuthing. Hosts:  Vincent Racaniello  and  Daniel Griffin Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Cryptosporidium ( TWiP 18 ) Letters read  on TWiP 239 Become a  patron...

TWiP 238: Eliminating sleeping sickness 05.07.2024

Michael Barrett joins TWiP to discuss progress in the elimination of human African trypanosomiasis caused by Trypanosoma brucei gambiense . Hosts:  Daniel Griffin ,  Dickson Despommier  and  Christina Naula Guest:  Michael Barrett Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Elimination of human  African trypanosomia...

TWiP 237: Pass the venison, deer with Marilyn Fabbri 21.06.2024

Marilyn Fabbri joins TWiP to reveal the case of a patient who became very ill after he and a number of friends attended a large dinner where venison and boar were served. Hosts:  Daniel Griffin ,  Dickson Despommier  and  Christina Naula Guest:  Marilyn Fabbri Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Toxoplasma g...

TWiP 236: Prime-and-trap vaccine for malaria 01.06.2024

Marion Avril of MalarVx, Inc. joins TWiP to discuss an accelerated prime-and-trap regimen using repRNA-based circumsporozoite vaccine. Hosts:  Dickson Despommier  and  Christina Naula Guest:  Marion Avril Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Please support our work at  microbe.tv/contribute repRNA-based  CSP...

TWiP 235: The case of the regurgitated wriggler 17.05.2024

TWiP solves the case of a man in his 50s reporting months of abdominal discomfort, who takes mebendazole and some time afterwards vomits a worm into the sink. Hosts:  Vincent Racaniello ,  Dickson Despommier ,  Daniel Griffin , and  Christina Naula Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Please support our work...

TWiP 234: Hookworms and a leech - parasites suck! 04.05.2024

TWiP discusses hookworm infection and the phase 1 clinical trial for a hookworm vaccine that could one day protect children from the hookworm anaemia, and reduce transmission of this infection. Hosts:  Dickson Despommier ,  Daniel Griffin , and  Christina Naula Subscribe (free):  Apple Podcasts ,  Google Podcasts ,  RSS ,  email Links for this episode Join the MicrobeTV  Discord server Please supp...

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