The Stem Cell Podcast

Intro: In June 2020, we attended the International Society for Stem Cell Research (ISSCR) virtual annual meeting! Here is the first of three special episodes from the meeting featuring Dr. Madeline Lancaster, Group Leader at the Medical Research Council Laboratory of Molecular Biology in Cambridge, UK, who presented on new directions for human brain organoids. Guest: Dr. Madeline Lancaster is a Gr...

Guest: Dr. Benoit Bruneau is the Director of the Gladstone Institute of Cardiovascular Disease. His lab uses mouse models and human iPSCs to investigate the transcription factor networks that regulate sets of genes critical for heart development. Featured Products and Resources: Muscle Cell News STEMdiff™ Cardiomyocyte Media and Supplements The Stem Cell Science Round Up New Bone Grafts from Stem...

Guest: Dr. Karl Koehler is an Assistant Professor of Otolaryngology at Harvard Medical School. His lab develops organoid systems to study human sensory organ development and function, and to model congenital diseases and develop regenerative medicine therapies for the inner ear and various craniofacial tissues. Featured Products and Resources: Dermal Cell News Wiley eBook: Organoid Research Techni...

Guest: Dr. Freda Miller is a Senior Scientist at the Hospital for Sick Children and Professor at the University of Toronto. Her research focuses on the cellular mechanisms that regulate development of the mammalian nervous system, with a particular interest in stem cells and trophic factors. Featured Products and Resources: Neural Disease Modeling Hub STEMdiff™ Neural Crest Differentiation Kit The...

Guest: Dr. Hans Clevers is a Group Leader at the Hubrecht Institute for Developmental Biology and Stem Cell Research. Dr. Clevers pioneered research into the Wnt signaling cascade, Lgr5 as a marker of tissue stem cells, and organoid technology. His group studies the molecular mechanisms of tissue development and cancer of various organs using organoids made from adult Lgr5 stem cells. Featured Pro...

Guest: Dr. Sheila Chari is the Editor-in-Chief at the journal Cell Stem Cell, and Executive Editor at Cell Press . After completing her postdoc, she moved away from the bench and became the Reviews Editor at Cell Stem Cell. As the Editor-in-Chief, Dr. Chari’s primary responsibilities are knowing and publishing the top stem cell discoveries, driving journal publishing strategy, and managing a globa...

Guest: Dr. Josef Penninger is the Director of both the Life Sciences Institute at the University of British Columbia, and the Institute for Molecular Biotechnology of the Austrian Academy of Sciences in Vienna, Austria. He was previously on the podcast to talk about his research developing human blood vessel organoids. Recently, Dr. Penninger’s team has identified a trial drug that can signi...

Guest: Dr. Darcy Wagner is an Associate Professor in the Lung Bioengineering and Regeneration group at the Lund Stem Cell Center. Her team uses a multidisciplinary approach to understand how the extracellular environment directs stem cell behavior for endogenous and exogenous lung tissue regeneration. Featured Products and Resources: #StemCellfie Contest Digital and Remote Resources for Your Lab

Guest: Among his many appointments, Dr. Deepak Srivastava is the President of the Gladstone Institutes and the International Society for Stem Cell Research, and co-founder of Tenaya Therapeutics . His lab investigates the gene networks that guide cardiogenesis by developing models of heart disease using patient-derived iPSCs and CRISPR technology. Featured Products and Resources: Webinar: Modeling...

Guest: Dr. Jeanne Loring is a Professor Emeritus and Director of the Center for Regenerative Medicine at the Scripps Research Institute, and the Co-Founder of Aspen Neuroscience. Her lab works on a diverse range of projects using iPSCs, including developing cell replacement therapies for Parkinson’s disease, sending neural organoids into space, and partnering with the San Diego Zoo to make iPSCs f...

Guest: Dr. Joy Wu is an Associate Professor of Medicine at Stanford University, and a a board-certified endocrinologist.  With both basic and translational research, her lab investigates stem cell therapies for bone formation and the prevention of cancer metastases to bone, as well as the bone marrow hematopoietic niche. Featured Products and Resources: Embryonic Stem Cell News mTeSR™ Plus The Ste...

Guest: Dr. Thomas Reh is a Professor of Biological Structure at the University of Washington School of Medicine. H is lab is studying retinal development and disease using organoids, and developing methods of transplanting stem cells for retinal repair in non-human primates. Their goal is to stimulate more effective regeneration in the retina to restore vision in people that have lost their sight....

Guest: Priye Iworima is a PhD student at the University of British Columbia. Her project is focused on developing and optimizing a differentiation protocol for generating insulin-producing cells derived from stem cells that could be used as a potential therapy for type 1 diabetes. She is also working on optimizing process parameters to facilitate the large scale manufacturing of the cells. Feature...

Guest: Dr. Kacey Ronaldson-Bouchard is an Associate Research Scientist in the Laboratory for Stem Cell and Tissue Engineering at Columbia University, focusing on biomedical engineering. She is also the co-founder of TARA Biosystems, which offers physiologically relevant human “heart-on-a-chip” tissue models for cardiac risk assessment and drug discovery applications. She also a strong supporter of...

Guest: Dr. Todd McDevitt is a Senior Investigator at the Gladstone Institutes. He is also Program Director of the University of California, San Francisco’s Bioengineering Graduate Program (joint with UC Berkeley), and a Professor at UCSF’s Department of Bioengineering and Therapeutic Sciences. His research focuses on engineering 3D, multicellular systems that can be used to study princ...

Guest: Dr. Nicole Quinn is the Associate Director of Scientific Communications at STEMCELL Technologies, and one of the people hard at work behind the scenes of the Stem Cell Podcast. After completing her PhD in genomics and discovering her love of communicating science, Nicole left the bench to pursue a science communications career in the biotech industry. She now oversees the comprehensive, glo...

Guest: Dr. Camilla Forsberg is the Co-Director of the Institute for the Biology of Stem Cells, and a Professor of Biomolecular Engineering at the University of California, Santa Cruz. Her lab seeks to understand the molecular determinants of hematopoietic stem cell fate decisions to ultimately prevent and treat both genetic and acquired disorders of the hematopoietic system. Featured Products and...

Guest: Dr. Peter Zandstra is the Director of the School of Biomedical Engineering at the University of British Columbia. His lab focuses on stem cell bioengineering, applying engineering design principles, computational modeling, and fundamental stem cell biology to study the mechanisms that control stem cell fate, and to develop technologies for the propagation of stem cells and their derivatives...

Guest: Dr. Celina Juliano is an Assistant Professor in the Department of Molecular and Cellular Biology at the University of California, Davis. Her lab studies development and regeneration in the aquatic animal Hydra , which undergoes continual self-renewal, lacks senescence and has incredible regenerative capabilities. Featured Products and Resources: STEMCELL Technologies Antibodies STEMCELL Tec...

Guest: Dr. Rameen Shakur is a Jansen Fellow in Cardiology and Personalized Medicine at the Koch Institute for Integrative Science at MIT, and the Founder of Cambridge Heartwear Ltd. His academic research focuses on modeling and understanding cardiac development using iPSCs. Insights from his basic and clinical research spurred the development of Cambridge Heartwear Ltd. , a medical device and algo...

Guest: Dr. Stephane Angers is a Professor and Associate Dean of Research in the Leslie Dan Faculty of Pharmacy at the University of Toronto . He is an expert in the field of signal transduction, working to understand the signaling mechanisms underlying the Wnt and Hedgehog families of growth factors and the large family of G protein-coupled receptors. Featured Products and Resources: Webinar: Usin...

Guest: Dr. Paul Burridge is a Professor in Pharmacology at Northwestern University’s Feinberg School of Medicine. Dr. Burridge’s lab uses human iPSCs and other next-gen technologies in pharmacogenomics, disease modeling, and regenerative medicine. Currently, they are focusing on modeling chemotherapy-induced cardiomyopathy using hiPSC-derived cardiomyocytes, endothelial cells, and fibroblast...

Intro: Back in June 2019, we attended the International Society for Stem Cell Research’s (ISSCR) annual conference in Los Angeles, California! Here is the last of three special episodes featuring interviews with some of the top researchers in the stem cell field, as well as with up-and-coming junior trainees who were challenged by Daylon to summarize their research in one minute. Junior Trai...

Guest: Dr. Pekka Katajisto is an Associate Professor at the University of Helsinki and at the Karolinska Institutet. His laboratory studies both stem cell intrinsic and extrinsic mechanisms altering tissue renewal capacity, and how such mechanisms ultimately result in the functional decline we recognize as aging. They mainly focus on the intestinal epithelium, studying asymmetric cell division, ce...

Intro: Back in June 2019, we attended the International Society for Stem Cell Research’s (ISSCR) annual conference in Los Angeles, California! Here is the second of three special episodes featuring interviews with some of the top researchers in the stem cell field, as well as with up-and-coming junior trainees who talked to Daylon about their research and experience at the conference. Junior...