The Stem Cell Podcast

Guest: Dr. Meritxell Huch is a Scientific Director at the Max Planck Institute of Molecular Cell Biology and Genetics and an Honorary Professor at the Technical University of Dresden. Her research focuses on liver and pancreas organoid models.  She discusses a protocol for liver mesenchyme and ductal cell organoid co-culture  and  generating bipotent stem cells from the liver . She also tells her...

Guest: Dr. Samantha Morris is an Associate Professor of Medicine at Brigham and Women’s Hospital and Associate Professor of Systems Biology at Harvard Medical School. She talks about dissecting and manipulating the genetic pathways that regulate cell identity. She discusses  tools to measure cell fate transitions  and incorporating  in silico  and  in vitro  experiments. Featured Products an...

Guest: Dr. Alfonso Martinez Arias is the CREA Research Professor in the Department of Systems Bioengineering of the Universitat Pompeu Fabra in Barcelona. He talks about his path to developmental biology research and developing gastruloids to model human development . He also discusses  standards for embryo models  and his recent research on  hematopoiesis . Featured Products and Resources: Keep c...

Guest: Dr. Behzad Yeganeh is an Associate Scientist at the Children’s Hospital of Eastern Ontario Research Institute and the University of Ottawa. His work focuses on lung development and injury. He talks about neonatal lung diseases and the mechanisms that regulate autophagy and apoptosis. Featured Products and Resources: Keep current with the latest in pulmonary cell news. Model the human...

Guest: Dr. Dmitriy Sheyn is an Associate Professor in the Department of Orthopedics and Regenerative Medicine Institute at Cedars-Sinai Medical Center. His lab focuses on the development of stem cell therapies for multiple musculoskeletal disorders caused by acute injuries and aging. He talks about ways to model disc degeneration and tendon injuries. He also discuses his lab’s work on  tendo...

Guest: Dr. Ludovic Vallier is the W3 Einstein Strategic Professor for Stem Cells in Regenerative Therapies at the Berlin Institute of Health and a Max Planck Fellow at the Max Planck Institute for Molecular Genetics. His lab uses stem cells to model embryonic development in vitro and to produce liver cells with an interest for cell therapy. He talks about modeling non-alcoholic fatty liver disease...

Guest: Dr. Ziyuan Guo is an Assistant Professor of Pediatrics at the Center for Stem Cell & Organoid Medicine at Cincinnati Children’s Hospital. He talks about in vivo reprogramming and cell and gene therapy in neurodevelopmental and neurodegenerative disorders. He also discusses  assembloids to model the blood-brain barrier  and strategies for organoid vascularization. Featured Products...

Guest: Dr. Irving Weissman is the Virginia and Daniel Ludwig Professor of Clinical Cancer Research and Professor of Pathology and Developmental Biology at Stanford University. Dr. Weissman was the first scientist to identify and isolate mammalian blood-forming stem cells in mice, and his work has contributed to the understanding of how a single hematopoietic stem cell can give rise to specialized...

Guests: Dr. Davide Marotta is the Program Director for In-Space Biomanufacturing at the International Space Station National Laboratory. Dr. Catriona Jamieson is the Director of the Sanford Stem Cell Institute at the University of California, San Diego.  In this special episode recorded in front of a live audience at ISSCR 2024 in Hamburg, Germany, they talk about the opportunities and challenges...

Guest: Dr. Valentina Greco is the Carolyn Walch Slayman Professor of Genetics and Co-Chair of the Committee on the Status of Women in Medicine at Yale University. Her research focuses on tissue homeostasis in the face of continuous cellular turnover, frequent injuries, and spontaneous mutations. She talks about her research on skin and hair follicle stem cells, the role of imaging techniques, and...

Guest: Dr. Sara Vasconcelos is a Senior Scientist and the John Kitson McIvor Endowed Chair in Diabetes Research at University Health Network. She is also an Associate Pr ofessor at the Institute of Biomedical Engineering at the University of Toronto. Her lab studies microvascular regeneration in cardiovascular diseases and diabetes, and are working to develop personalized patient-derived organ-chi...

Guest: Dr. Sebastian Diecke is a Group Leader and Stem Cell Core Director at the Max Delbrück Center, where his research focuses on iPSCs and organoid models. He talks about the early days of iPSC research, developing organoids from endangered rhinoceros , and  modeling Huntington’s and other diseases . Featured Products and Resources: Check out the program for ISSCR 2024, happening July 10-...

Guest: Dr. Shukry Habib is an Associate Professor in the Department of Biomedical Sciences at the Université de Lausanne. His lab works at the intersection of stem cell biology, biophysics, and tissue engineering to investigate how tissues form. He talks about developing a transplantable bandage for bone repair  and the role of Wnt signaling and cytonemes in development. Featured Products and Reso...

Guest: Dr. Shankar Srinivas is a Professor of Developmental Biology in the Department of Physiology Anatomy and Genetics based in the Institute for Developmental and Regenerative Medicine at the University of Oxford. He is also a Zeitlyn Fellow and Tutor in Medicine at Jesus College. Using mouse and human embryos as model systems, his group looks at the control of patterning and morphogenesis duri...

Guest: Dr. Pierre Vanderhaeghen is a Professor and Principal Investigator at VIB-KU Leuven Center for Brain & Disease Research. His lab studies the mechanisms of cortical development and brain evolution. He talks about  species-specific neuronal development ,  human neuron excitability , and playing in a rock cover band! Featured Products and Resources: Register now for ISSCR 2024, taking plac...

Guest: Dr. Ryan Flynn is a Principal Investigator at Boston Children’s Hospital and an Assistant Professor in t he Stem Cell and Regenerative Biology Department at Harvard University. His lab explores the interface between RNA and glycans. He talks about the discovery of glycoRNA and the chemistry of the RNA-glycan connection . He also discusses the effects of glycans on stem cell function a...

Guest: Dr. Blair Benham-Pyle is an Assistant Professor at Baylor College of Medicine. She talks about how multipotent cells in  Schmidtea mediterranea  enable  whole-body regeneration . She also discusses the effects of the mechanical environment on stem cell fate. Featured Products and Resources: Register for ISSCR 2024! Get updates about new mentorship content from Lab Coats & Life™ The Stem...

Guests: Dr. Amander Clark is the President of the International Society for Stem Cell Research (ISSCR) and Founding Director of the Center for Reproductive Science, Health, and Education at the University of California, Los Angeles. Dr. Agnete Kirkeby is a Program Chair of the ISSCR Annual Meeting, Associate Professor at Lund University and the University of Copenhagen, and Group Leader at the Nov...

Guest: Dr. Marissa Scavuzzo is an HHMI Hanna H. Gray Fellow at Case Western Reserve University School of Medicine. Her research focuses on enteric glia regulation in the healthy and diseased gut. She talks about how glial cell subtypes affect intestinal motility and her experience receiving NYSCF and HHMI fellowships. She also talks about bringing science to underserved schools in Cleveland . Feat...

Guest: Dr. Ritu Raman is the d’Arbeloff Career Development Assistant Professor of Mechanical Engineering at MIT, where her lab uses robotics and tissue engineering to treat muscle loss. She talks about  light-activated muscle grafts ,  magnetic microparticles to control forces exerted on cells , and strategies for science communication. Featured Products and Resources: Register now for ISSCR 2024,...

Guest: Dr. Shiri Gur-Cohen is an Assistant Professor of Medicine in the Division of Regenerative Medicine at UC San Diego. Her lab studies epithelial stem cells throughout their lifetimes. She talks about  lymphatics in the intestinal stem cell niche , 3D imaging techniques, and  sharing her science with a wider audience . Featured Products and Resources: Submit your abstract for ISSCR 2024! Get u...

Guest: Dr. Malin Parmar is a Professor at Lund University and a New York Stem Cell Foundation – Robertson Investigator. Her research aims to understand cell fate specification in the developing brain and in human neural progenitor cells using cell-based models of neuronal differentiation. She talks about using assembloids to model the dopaminergic system ,  direct reprogramming somatic cells into...

Guest: Dr. Olivier Pourquié is the Frank Burr Mallory Professor of Pathology and Professor in the Department of Genetics at Harvard Medical School. His work focuses on the segmentation clock and the development of muscles and vertebrae. He talks about studying somitogenesis  in vitro  and his work on  brown fat development . Featured Products and Resources: Register now for ISSCR 2024! Derive and...

Guests: Dr. Hwee Goon Tay is an Assistant Professor at the Duke-National University of Singapore Medical School and Dr. Beau Fenner is an Ophthalmologist at the Singapore National Eye Centre. Their work focuses on cell therapy for degenerative retinal diseases. They talk about strategies to slow degeneration and potentially restore vision. Featured Products and Resources: Enter to win up to $500 U...

Guest: Dr. Jose Polo is a Professor of Epigenetics and the Director of the Centre for Epigenetics at the University of Adelaide. He is also a Professor in the Department of Anatomy and Developmental Biology at Monash University. His lab studies the transcriptional and epigenetic mechanisms that govern cell identity. He talks about his team’s work on cell fate,  iBlastoids , and  placental mo...