The Poison Lab

In this enlightening episode, Ryan engages in a deep conversation with Dr. Paul Hutson, PharmD, a renowned researcher in the field of psilocybin and director of the Transdisciplinary Center for Research in Psychoactive Substances at the University of Wisconsin Madison. Dr. Hutson shares his extensive knowledge and insights into the promising role of psilocybin in the treatment of depression and su...

New Art and New Tox Trinkets. If you want to share your tox joy in the real world, find some trinkets here: https://www.etsy.com/shop/thepoisonlab A Morel Dilemma Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member Ad free episodes Bonus content and early access Discounts and give aways on GOTA PICCEM Mushroom card ga...

This episode is a a high yield "just the facts" break down of the recently released "Management of Acetaminophen Poisoning in the US and Canada Consensus Statement" from the American Academy of Clinical Toxicology, American College of Medical Toxicology, Americans Poisons Centers, and the Canadian Association of Poison Centers. Listen to be informed on the most recent treatment recommendations. Th...

Mini episode- High-yield over view of Management of Acetaminophen Poisoning in the US and Canada Consensus Statement  In this Ryan sits down with Dr. Richard Dart MD, PhD. He is the lead author of the recently released "Management of Acetaminophen Poisoning in the US and Canada Consensus Statement" from the American Academy of Clinical Toxicology, American College of Medical Toxicology, Ameri...

Dr. Frank Paloucek, PharmD, DABAT (@itsalltox) joins the show. He was one of the very first emergency medicine pharmacists and one of the original board-certified clinical toxicologists (DABAT). He is now a proudly retired professor emeritus at The Univeristy of Illinois at Chicago. In his tenure there he spent nearly 20 years as the program director for their clinical pharmacy residency, was an i...

In this episode Ryan explores the concept of brain death and the implications of drug overdoses causing false positive diagnosis of brain death. He is joined by an author of the ACMT Position statement on brain death in overdose (Dr. Andrew Stolbach MD) as well as authors of two case reports (neuro critical care physician Dr. Ranier Reyes and emergency physician Dr. Doug Stranges) involving buprop...

Dr. Adam Blumenberg, MD (@ABlumenbergMD) Join's the show. He is an emergency medicine physician, medical toxicologist, and Assistant Professor at Columbia University Medical Center in New York City. He hosts his own toxicology youtube series (www. ToxicHistory.com) and has developed multiple free medical education software programs in toxicology (www.toxicrunner.net) and medical simulation (www.me...

Ready for a high-octane dose of knowledge? 🔥🧠 Ryan's got you covered with this electrifying mini-episode on managing a bupropion overdose! 💊💥  Beware - there are plenty of pitfalls you'll want to avoid. Check out the full episode and other mini-episodes for even more tips and tricks! 🎧👀 Bupropion is the #1 antidepressant cause of major (life threatening) reported to U.S. Poison Centers...

What Do Bath Salts, Face-Eating Zombies, and Antidepressants Have in Common? In this episode of The Poison Lab , Ryan is joined by Dr. Filip, Dr. Olives, and Dr. Reyes to discuss a unique and heartbreaking poisoning scenario involving an antidepressant now recognized as the #1 cause of major life-threatening effects in antidepressant overdoses in the U.S. Check out the mini-episodes for more detai...

Seizure Risk: Patients can seize 8–24 hours post-ingestion . Neurologic symptoms and tachycardia often precede seizures. Delayed Symptoms: Co-ingestions may mask tachycardia, and symptoms can be significantly delayed. Key Management Advice: Do not discharge patients without consulting a toxicologist or poison center about observation times. Do not dismiss tachycardia and anxiety as situational in...

Rohr 2004- Gap junction blockade can cause a wide QRS   Vink 2004 Connexin 43 is the most important protein for connexon formation and cardiac signal transmission Callier 2012- Bupropion does not block sodium channels, and does exhibit similar effects on the cardiac action potential as known gap junction   Burnham 2014 Bupropion has an IC50 for connexin 43 >50 uMol, larger than other...

All published abstracts can be found here  Abstracts Category 1: Amlodipine Vasoplegia Abstract 1: Vasodilation in patients with calcium channel blocker poisoning treated with high dose insulin: a comparison of amlodipine versus non-dihydropyridines Study of HDI on propranolol poisoned pigs Study of Minnesota HDI protocol Abstract 2: Amlodipine anxiety: a 10-year review of amlodipine associat...

Do you think you know the cause of these symptoms? Send your guesses to toxtalk1@gmail.com to take part in episode 19 A Morel Dilemma Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member Ad free episodes Bonus content and early access Discounts and give aways on GOTA PICCEM Mushroom card game The GOTTA PICCEM Poisonous...

Dr. Emily Kiernan, DO (@em2kiernan) an emergency medicine physician and medical toxicologist with Emory university school of medicine joins the show to solve toxic cases, opine on recent healthcare related poisoning, and dive head first into the bongwater on this episode. (Remember friends, don't drink the bong water). Recent Healthcare poisoning in the news Nurse reportedly feeding children insul...

Phenibut is an emerging and unfamiliar drug taking hold in the US that is readily available online and legal to obtain. It acts as a GABA-B agonist and carries risks of dependency and withdrawal. In this episode Ryan interviews phenibut users as well as experts involved in phenibut treatment. They explore the history, current trends, toxicity, and management of phenibut, a novel GABA-B agonist. He...

Do you think you know the cause of these symptoms? Send your guesses to toxtalk1@gmail.com to take part in episode 16 A Morel Dilemma Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member Ad free episodes Bonus content and early access Discounts and give aways on GOTA PICCEM Mushroom card game The GOTTA PICCEM Poisonous...

Dr. Joshua Trebach, MD (@jtrebach) joins the show for some toxic sleuthing of fishy poisonings and answers questions from reddit.com/r/askdrugs. Case report Ryan Feldman wrote about himself Stump the Tox cases Case #1 Case #2 case series from Dr Jillian Theobald Case #3 Case #4 Ask drugs Fanconi syndrome in expired tetracycline A Morel Dilemma Support the show Review the show where ever your liste...

In this episode Ryan and Toxo dive into a widely available prescription poison with a frightening ability to cause rapid neurologic and cardiovascular decline, and the best part, it looks like candy! Digoxin kinetics Amiodarone overdose Post market safety review Review of published exposures and severe outcomes from US poison center Case from the show A Morel Dilemma Support the show Review the sh...

Send in your guesses to toxtalk1@gmail.com A Morel Dilemma Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member Ad free episodes Bonus content and early access Discounts and give aways on GOTA PICCEM Mushroom card game The GOTTA PICCEM Poisonous Mushroom Game! The Poisonus Fungus Amongus Children's Book! Full book read...

Dr. Howard Greller, MD (Sirius XM Doctor Radio Emergency Medicine Show, Dantastic Mr Tox & Howard, Tox & Hound) joins the show. A FANTASTIC episode complete with toxic sleuthing of fatal poisoning cases and answering questions from reddit.com/r/askdrugs. Music from Pixabay Additional information on toxins from fatal poisoning cases  Toxin 1 Toxin 2 Toxin 3 Toxin 4 Popper article refer...

No episode today. Head here for the live radio show!  Join us next show for Dr. Howard Greller of  Sirius XM Doctor Radio, Dantastic Mr Tox & Howard,  and Tox & Hound Find the article about the poison lab here   A Morel Dilemma Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member Ad free epi...

In this episode Ryan and Toxo dissect the fascinating underbelly of illegal cosmetic procedures and breakdown the toxicities that arise from them. Intro Case report of hemolysis after sodium deoxycholate injection  History Epidemiology ASPS stats Florida Unlicensed Activity Unit  Cost of surgeon fee for buttock implant 2018 Recent new stories Botox and Bubbles grifter Quick bio on cases...

Send in your guesses to toxtalk1@gmail.com A Morel Dilemma Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsletter!) Join as a supporting member Ad free episodes Bonus content and early access Discounts and give aways on GOTA PICCEM Mushroom card game The GOTTA PICCEM Poisonous Mushroom Game! The Poisonus Fungus Amongus Children's Book! Full book read...

In this episode of toxicologist vs internet guest Dr. Andrew Farkas, MD joins the show. This a great episode that covers everything from the drugs you would need in the apocalypse to what to worry about if your cats are dying. Complete with toxic sleuthing of fatal poisoning cases and answering questions from reddit.com/r/askdrugs. Research from Dr Farkas Additional information on toxins from Fata...

In this episode Ryan and Toxo take a closer look at ketamine induced irreversible bladder damage. History Discovery of Ketamine Melamine outbreaks Clinical Effects Index cases Survey of Ketamine use prior to symptoms Mechanism/Treatment Mechanism/Treatment systematic review Rat models A Morel Dilemma Support the show Review the show where ever your listening Get Messages from Toxo (Join the Newsle...