The Gateway

The FDA recently approved two cell-based gene therapy treatments for the blood disorder. Doctors and advocates believe the therapy could bring relief to the nearly 2,000 St. Louisans living with the disease. However, many are questioning the accessibility, their costs and risks.

The St. Louis Cardinals start their 2024 season tomorrow afternoon in Los Angeles against the Dodgers. Last year, the redbirds had their first losing season since 2007. There are tempered expectations that this year will be better.

Beauty school has made its way to incarcerated women at the St. Louis County Justice Center. The aim is to address recidivism with hot tools and clippers.

The 2024 Missouri Legislative Session resumes today after a week away from the Capitol. With only roughly two months left in the end of session, GOP priorities include passing a resolution that if later approved by voters, would make it harder to amend the state’s constitution as well as measures on education and crime.

Damon Davis has worked in many art forms, including sculpture, painting and film. His latest work is a multi-genre opera inspired by Afrofuturism.

In the early 1900s many race massacres where white mobs attacked and killed Black people across the country, including in East St. Louis and Tulsa, Oklahoma. The oldest known survivor of the Tulsa massacre spoke about it at Southern Illinois University Edwardsville.

Answers to the main question about the Clayton campus' planned 2025 closure and reaction from students with an uncertain future.

Two wildfires consumed more than 1,000 acres of the Mark Twain National Forest in late February. Firefighters contained the burns, but the unseasonably warm and windy conditions that let them spread quickly underscore the importance of the forest service's plans to set some fires on purpose.

It’s illegal to fight roosters in the U.S. yet raising game fowl is a big business. There have been recent efforts in some states to lower the penalties for cockfighting. Animal rights activists call foul, while breeders say they’re simply protecting their right to raise chickens.

St. Louis has roughly 20-thousand vacant properties spread across the city. And responding to this challenge will require a fair amount of cash and investment.

One month ago today, Kansas City was shaken when the Chiefs Super Bowl celebration turned into a mass shooting. Since then, people around the country have donated millions to aid the victims. Now, the community needs to figure out the landscape of need.

Kahlil Robert Irving makes sculptures at his spacious studio in South St. Louis that he exhibits around the world. His latest show, an innovative mix of ceramics and digital collage, is at the Kemper Art Museum.

The GOP candidates for Madison County board chairman, Kurt Prenzler and Chris Slusser, used to be allies — but are now bitter rivals. Since no Democrat is running, whoever wins the primary will be the chairman.

Farms across the Midwest use biosolids—a type of byproduct from wastewater treatment plants—to fertilize their land. But toxic chemical could be contaminating that fertilizer, along with millions of acres of farmland.

In the GOP primary race to represent southern Illinois in Congress, incumbent Mike Bost is being challenged by Darren Bailey. The two Republicans have tried to differentiate themselves — despite having similar policy positions. How are they different and what are their priorities for the 12th congressional district?

St. Louis’ major league soccer team has started its second season as the newest member of the league. But this summer, the team will not be playing in the U.S. Open Cup. The decision by MLS has angered the supporters groups that have been called the backbone of the fan base.

One of the most contentious topics for members of Congress right now is whether the United States should continue giving military support and money to Ukraine. It’s an issue that’s divided candidates in Missouri’s U.S. Senate contest — as well as GOP members of Missouri’s House delegation.

The Francis Howell School District made national headlines when it canceled its Black History and Black Literature courses. After protests from teachers and students, the board agreed to reinstate it, only it was, in the board’s words, a politically neutral curriculum. A new version will be before the board later this month.

Parts of the Midwest including Missouri lack reliable data on Hispanic maternal mortality rates. A new investigation shows that while an accurate count is challenging, it may also cause underserved populations to miss out on health care resources.

Women now make up a majority of veterinarians in the United States. But they still face skepticism and even discrimination in rural areas where there’s a shortage of veterinarians.

Abortion rights activists in Missouri are feeling a surge of momentum around a ballot measure legalizing the procedure. But foes of abortion rights are fighting the effort — both inside and outside of the state legislature.

Most Illinois teachers feel parents and administrators support the state’s efforts to teach students about racially inclusive history. That’s according to a new University of Illinois survey of teachers.

Lincoln University students and alumni are still grieving the death of a beloved administrator. Antoinette “Bonnie” Candia-Bailey died by suicide in January. Her passing has brought awareness to the Black mental health crisis.

The sixth-generation family run A.E. Schmidt company hasn't changed much in 150years. The oldest American manufacturer of billiards tables is carving history into every pool table at a factory in south St. Louis.

Many Asian people in the area say they miss spending the holiday with family back home, but they try to keep the traditions alive in St. Louis. And, St. Louis Symphony Orchestra will perform a musical melding of Radiohead and Brahms.