The Clinical Research Podcast

An interview with Dr Chloe Anthias, medical director of the new Cell Collection Centre has just opened by Anthony Nolan charity as part of our NIHR Nottingham Clinical Research Facility. Links a little while ago I talked to Prof Mark Bishton, who’s an oncologist at the hospital about stem cell research. Listen here NIHR Nottingham Clinical Research Facility To find out more about the Anthony Nolan...

This bulletin intro was brought you by Harriet Anderson from Research and Innovation Nottingham University Hospitals NHS Trust. Keep listening for more team members introducing other episodes. If you're a clinical researcher at NUH or the University of Nottingham and want to be voice of the podcast contact us at ⁠R&Icomms@nuh.nhs.uk⁠. Tags: #SAPhEStudy, #Nanopore #SequencerDevice, #Tech, #...

Asthma is one of the most common conditions - there are 8 million of us in the UK who suffer from it.  t can range from the needing a quick puff on your inhaler if you exercise and there’s a lot of pollen about it, to serious, fatal attacks, there’s still a lot we don’t know. That’s what this interview with our respiratory physician Matthew Martin is all about. One of the things we’re not sure abo...

This bulletin intro was brought to you by Ian Kingsbury from East Genomics Nottingham University Hospitals NHS Trust. Keep listening for more team members introducing other episodes. If you're a clinical researcher at NUH or the University of Nottingham and want to be voice of the podcast contact us at ⁠R&Icomms@nuh.nhs.uk⁠. #BioResource, #GLADstudy, #NIHR, #Chest drains, #PneumocystisPneu...

One of the fundamentals of clinical research is the ‘blind’ bit of the double-blind placebo controlled trial. If neither the researcher nor the participant know whether they’re getting placebo or the drug, it removes the chances that they’re unconsciously  responding in the way they think they should.  The placebo effect can account for up to 30% of a difference, so it has to be dealt with. But if...

The intro this week was from Harriet Anderson, who works in the Research and Innovation team at Nottingham University Hospitals NHS Trust. Keep listening for more team members introducing other episodes. If you're a clinical researcher at NUH or the University of Nottingham and want to be voice of the podcast contact us at R&Icomms@nuh.nhs.uk . Links Mental health citizen science - www.gla...

You’d think that clinical researchers would welcome surprises - but they don’t. Even if the results are new and groundbreaking, they want their trials and studies to run in a predictable, controlled way,. And that ability to deliver a total lack of surprise is one of the reasons that cancer research at Nottingham University Hospitals NHS Trust has made it into the top flight in the UK working with...

Staff at the NIHR Nottingham Clinical Research Facility talk about the UCAB trial. The facility worked with Swedish pharmaceutical Umecrime Cognition to study using a new molecule as a treatment for Primary Biliary Cholangitis (PBC) for patients with severe symptoms of fatigue and cognitive impairment. Quick takeaways -      • one of only two UK locations for first stage drug trial     • kept to t...

Contacts for his episode: COACH trial for hearing aids vs cochlear implants - More information from coachtrial.ac.uk or email coach@nottingham.ac.uk Ultrasound probe for people with trauma injuries - contact Georgia Melia at georgia.melia@nuh.nhs.uk The studies in Norfolk and Leicester into communities and genomics - www.eastgenomics.nhs.uk or email the East Genomic Medicine Service Alliance (GMSA...

Bulletin 9 - developing treatments for cystic fibrosis, depression, alcoholic liver disease and eczema In this episode: We pick up on presentations from the NIHR Nottingham BRC conference, from: Dr Helen Barr, on matching medicines to gene for CF patients Prof Richard Morriss on treating depression and anxiety with transcranial magnetic stimulation - https://www.mindtech.org.uk/news-events/latest-...

In this bulletin: Testing the Respirasense breathing monitor from PMD Solutions - https://www.pmd-solutions.com - https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3944-respirasense-trial Bone graft augmentation and gene therapy research with Theragenix - https://theragenix.health/ https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3942-nearly-1m-for-pioneering-gene-therapy-formul...

In this bulletin: Secure Data Environments - ⁠https://transform.england.nhs.uk/key-tools-and-info/data-saves-lives/secure-data-environments/⁠ Prof Guru Aithal appointed new medical lead for the Eastern Genomic Medicine Service Alliance - ⁠https://www.eastgenomics.nhs.uk Showcase of gastro intestinal research at Nottingham⁠ Meet the respiratory research team - with pizzas Networking for early caree...

Links to show items Equity in Doctoral Education through Partnership and Innovation programme - https://www.ntu.ac.uk/c/equity-in-doctoral-education-through-partnership-and-innovation MRI PhDs - https://www.nottingham.ac.uk/research/beacons-of-excellence/precision-imaging/current-opportunities/studentships/nihr-nottingham-brc/index.aspx AERIFY study - https://www.hra.nhs.uk/planning-and-improving-...

Spend an evening with blood, urine, saliva and Nottingham researchers, looking to the future of research at NUH, helping children and young people with mental crises, and how to show a researcher you love them. Links: BioResource event booking - https://www.eventbrite.com/e/574447577167 NUH medical director Keith Girling on why the Nottingham BioResource is good for patients – https://youtu.be/AC4...

In this clinical research bulletin from Nottingham: Notts County legend Les Bradd has been helping our researchers investigating football-related injuries. https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3927-notts-county-fc-legend-les-is-helping-researchers-investigating-playing-injuries We hit national and international headlines this week for study which identified 500 genes linked t...

In this episode - clinical research news of ASSIST MS study, World Hearing Day, NIHR researcher appointments, Liver Partnership launch, and the Tummy Tracker app for cystic fibrosis patients. Links ASSIST-MS - https://www.nihr.ac.uk/news/ground-breaking-ai-research-aims-to-improve-tests-and-treatments-for-thousands-of-patients/32852 World Hearing Day - https://worldhearingday.org/ Nottingham partn...

Weekly updates from research and innovation team at Nottingham University Hospitals NHS Trust and NIHR Nottingham Biomedical Research Centre Links Methotrexate study - https://nottinghambrc.nihr.ac.uk/about-nottingham-brc/news/3925-methotrexate-study Tinnitus research - https://www.mdpi.com/2076-3425/12/4/484 PrAISED study -  Video - https://youtu.be/VB6GET95Sgg - https://www.nottingham.ac.uk...

We’ve launched a new podcast, it’s a short update on research in Nottingham, and it’s for both researchers and anyone interested in clinical research and it’s out every fortnight. The first episode covers the Nottingham methotrexate study which has piqued worldwide interest and sparked tens of thousands of tweets, as well as research into dementia, tinnitus and breast cancer. We’ve also got detail...

As the NIHR Nottingham Biomedical Research Centre embarks on its second tranche of funding, we're developing our existing partnerships with other clinical research organisations in the East Midlands, especially Nottingham Trent University. One of our closest links there is Professor John Hunt, who's Head of NTU's medical technologies and advanced materials research theme. He's also just taken on a...

Chronic lung diseases are the third biggest cause of death in the world, and in Nottinghamshire, about 1 in 8 people have been diagnosed with asthma or COPD - so finding new treatments is high on the list for clinical researchers. And our particular expertise here is understanding how the disease works at a cellular level and it's why we're part of new £8.8million study funded by the Wellcome Trus...

October is a vital and important month for many ethnic minorities especially the Black community. In the UK Black History Month is celebrated every year with a different theme. This year’s theme is ‘Action not words’. In recent years we have seen the rise of Black communities and individuals sharing their experiences about the inequalities and injustices they go through. In this episode we speak t...

Leaps forward in the understanding of the Human Genome in recent years stand to offer huge benefits to patients - including the possibility of personalised care. As a large acute hospital, Nottingham University Hospitals NHS Trust is one of the organisations at the forefront of this exciting health revolution, which also brings some challenges. But what does Genomics mean in reality to healthcare...

Genomics is the future of healthcare which we’re told will revolutionise how patients are treated – but what is it, exactly? And how can healthcare professionals use it day to day? Dr Matt Hall, a Consultant Nephrologist at Nottingham University Hospitals NHS Trust, is the medical lead for the Genomics Medicines Service Alliance (GMSA), which means he’s leading how genetic medicine is becoming emb...

Nottingham's long been a leader in researching and treating blood cancer - we pioneered blood stem cell transplantation and we're still one of the biggest centres in the UK. We bring together oncology, clinical haemotology, neuro imaging and surgery and over the last five years we've increased our experimental cancer research trials by 30 percent. So it's naturally one of the priorities of our new...

Newly appointed NIHR Nottingham Clinical Research Facility deputy director Prof Chris Fox talks about cancer research.