SciPod

Most human diseases are localised in terms of their location but currently, injected or orally administered drugs are evenly distributed all over the body and thus, act indiscriminately. The targeted delivery of medication to the exact site where it is needed is a common theme in science fiction but thanks to Professor Richard Klemke and his team at the University of California San Diego’s Moores...

Although human immunodeficiency virus (HIV) is still prevalent worldwide, life-saving antiretroviral drugs can now prevent an infection from progressing into acquired immunodeficiency syndrome (AIDS). Nevertheless, people who are HIV-positive are still at increased risk of developing neurological disorders and cardiovascular diseases, known as co-morbidities. Professor Michael Bukrinsky from the G...

People who live close to busy roads and highways are exposed to high levels of traffic-related air pollution. This puts them at risk of significant health difficulties such as high blood pressure, heart attacks and cancer. The Community Assessment of Freeway Exposure and Health Studies led by Dr Doug Brugge from the University of Connecticut represent community-engaged research into the biological...

Epilepsy is a chronic, long-term disease in which abnormal activity in the brain leads to repeated seizures, and it affects nearly 70 million people worldwide. The exact mechanisms behind epileptic seizures are still poorly understood. However, we do know that epilepsy can be caused by changes in the network structure of our brains and that seizures may be a result of spontaneous excessive brain s...

Non-human primates play crucial roles in sustaining natural ecosystems worldwide. However, approximately 68% of primate species are now at risk of extinction, mainly due to agriculture and the depletion of natural resources. Dr Alejandro Estrada at the National Autonomous University of Mexico, Dr Paul A. Garber at the University of Illinois-Urbana, and a group of scientists from various parts of t...

Addressing the skills shortage within scientific sectors requires a targeted approach for attracting and retaining students in STEM education. Summer Opportunities in Agricultural Research and the Environment (SOARE), SOARE: Strategic Work in Applied Geosciences (SWAG) and AgDiscovery, three innovative programs at the University of Maryland, provide a gateway for continued education, particularly...

Our intestines contain millions of bacteria, known as our microbiota, which secrete compounds and play a key role in keeping us healthy. These bacteria don’t just affect the health of our digestive system, they can influence organs as far away as the brain. Dr Francesca Ronchi at Charité Universitätsmedizin in Berlin is determining the role of the microbiota in the prevention and development of ne...

The perspectives and characteristics of specific historical periods are often reflected in the literary texts produced and circulated at the time. Dr Andrea Binsfeld, an Associate Professor at University of Luxembourg, has conducted several studies examining narratives of slavery in ancient texts, including novels and political discourses. Her analyses outline, from a different perspective, the de...

Dr Lars Oddsson, CTO of RxFunction and Adjunct Professor at the University of Minnesota is co-inventor of a wearable device called Walkasins® to help improve balance and reduce the risk of falls in people with sensory peripheral neuropathy. The walk2Wellness trial incorporated five clinical sites where they demonstrated that by replacing sensory stimulation for balance, this prosthetic device can...

The Hilbert space formulation is a central idea in quantum theory, but the ideas used by physicists to interpret the formulation widely differ. Furthermore, concepts in quantum mechanics are very abstract to those outside the field. Professor Inge Helland from the University of Oslo approaches these problems through what he calls ‘conceptual variables’, which belong to the minds of one or more con...

Orthodox Christians often use tactile gestures during acts of religious devotion. However, during the COVID-19 pandemic, such gestures had the potential to increase the spread of the virus. Dr Timothy Carroll, Dr Nicholas Lackenby and Ms Jenia Gorbanenko at University College London undertook an ethnographic study focused on how Orthodox Christian communities responded to public health advice that...

Lights and sirens on ambulances are used in emergencies to accelerate the transport of critical patients to hospital but unfortunately, can increase the risk of motor vehicle collisions. Emergency medical service personnel are those most commonly injured during these collisions and the general public account for the majority of fatalities. Shane Urban at UC Health University of Colorado Hospital,...

In many African countries, attitudes towards gender and sexual minorities are overwhelmingly negative. This could be partly due to religious norms and beliefs. However, empirical studies examining how religious leaders in Africa view such minority groups are still scarce. David Kuria Mbote of the Kuria Foundation for Social Enterprise and researchers from Saint Paul’s University in Kenya and insti...

The pH inside our cells is constantly changing, but also carefully controlled within certain limits. Dynamic intracellular pH (pHi) is essential for normal cell behaviours, but when it becomes dysregulated, it can enable an array of diseases from cancer to Alzheimer’s. Dr Diane Barber from the University of California San Francisco has carried out extensive research into how normal pHi dynamics re...

The relatively new field of paediatric pharmacovigilance aims to improve the clinical care of children by understanding and appropriately managing the risks of medicines administered to this group of patients. Dr Beate Aurich is an established expert in this field, and with colleagues, has published an article on the practical aspects of paediatric pharmacovigilance. She notes that the assessment...

As the strains of bacteria that are not killed by antibiotics proliferate, increasing numbers of people are at risk of severe illness and even death. Dr Rogier Hopstaken from Star-shl Diagnostic Centres in the Netherlands has shown that a simple, yet effective technique may be the answer to antibiotic over-prescription. A C-reactive protein test at primary points of care can indicate whether a pat...

In 2009, the US National Research Council Committee on Identifying the Needs of the Forensic Sciences Community published a report highlighting the need to estimate the validity of expert opinions in forensic disciplines. These include the opinions of firearm examiners, who are trained to identify firearms and other weapon-related evidence during criminal investigations. Dr Susan Vanderplas at the...

Sickle cell disease is an inherited disorder affecting the blood. Recently, promising new treatment strategies have emerged involving gene editing therapies and the administration of stem cells directly into the developing foetus in the womb. Along with his colleagues, Dr Panicos Shangaris at Kings College London, has conducted a comprehensive review of the available evidence to support this novel...

For decades, linguists and psychologists have been trying to understand the fascinating ways in which humans communicate with each other in different real-world settings. Overall, spoken communication involves a mixture of words, facial expressions, and gestures. Dr Holly Keily, a researcher at the University at Buffalo, has recently carried out a study specifically exploring how speakers explain...

The greatest challenge for ageing populations is that vaccines can be less protective for the elderly due to the age-related decline of the immune system. This means that improving the efficacy of vaccines in the ageing population is crucial to public health. Dr Lei Jin [lā] [jin] and colleagues from the University of Florida set out to develop a novel strategy to directly address this key issue.

Traditional Chinese Medicine has been used in the treatment of disease for centuries, although its potency is often overlooked by researchers. Dr Yu-Ling Ma and colleagues in the Oxford Chinese Medicine Research Centre at the University of Oxford have focused on a multi-component herbal medicine called Xin Su Ning in the treatment of cardiac arrhythmia to elucidate the mechanism of action and phar...

By stacking layers of atom-thick materials on top of each other, researchers are opening up a whole host of exciting new possibilities for technology and scientific research. Particularly interesting properties in these 2D materials could be achieved by stacking three or more of these layers – but so far, the large-scale production of these structures has proven difficult. Using carefully applied...

Interactions between positive and negative ions are important processes in nature. However, there is a lack of experimental facilities designed to study them in detail. This picture could now be changing thanks to DESIREE: a facility where different ion beams can be stored and cooled for extensive periods within separate rings, before colliding with each other. Run by an extensive team of physicis...

Over recent decades, the use of digital technologies has increased exponentially worldwide, bringing significant changes to daily life. Like most societal transformations, this process of ‘digitalisation’ has had both positive and negative aspects. Dr Jens Allwood, Professor Emeritus at the University of Gothenburg, has recently published a paper exploring some of the darker elements of digitalisa...

The introduction of new research or technologies for public health into a community is often challenging since complex scientific concepts coupled with jargon can cause disengagement and mistrust, whilst language barriers and cultural differences can complicate things further. Target Malaria is a not-for-profit research consortium that aims to develop and share new, cost-effective and sustainable...