SCHOTT Pharmaversity™

Ampoules were the first container developed to store injectable drugs. Still today is the most used container worldwide contributing to save lives around the globe. Learn at this webinar how to improve your filling process and get insights about how you can cope with common challenges associated with ampoule processing and handling. From an end user perspective, we will have a look on how the use...

Launching a drug into a prefilled syringe has many advantages. Prefilled syringes eliminate some of the drug preparation steps and therefore reduce the risk for medical errors and safe valuable time for health care professionals to focus on patients. However, selecting the right prefillable syringe, being a complex drug delivery system, is not an easy task. Knowing available materials, the key dif...

When filling in aseptic environments, a strict contamination control is indispensable. This requires that all introduced components must be free from contamination. This also applies to the outer packaging of ready-to-use containers, namely tub and Tyvek®, as these components enter the aseptic core before delidding of the tub to take out the primary packaging containers for filling. As the current...

Due to large, complex and therefore sensitive molecules, biologics pose a challenge to standard drug containment solutions. Their sensitivity towards leachables, the necessity of lyophilization or their tendency to adsorb might require a special inner glass surface quality. Storage at deep cold temperatures pose additional challenges with regard to container closure integrity and strength. Their h...

Medication errors and shortages of drugs are some of the most urgent issues at hospitals. The WHO estimates the total global costs of medication errors are 42 Billion USD per year. On the other hand, drug shortages may adversely affect patient care by compromising or delaying medical procedures and are becoming more frequent globally. This session will explore how polymer pre-fillable syringes can...

Efficiency and flexibility is key in pharmaceutical fill & finish settings. Especially when facing smaller batch sizes. In these environments quick change overs from one drug to another are of utmost importance. But what if the transition does not only cover various drug types, but also require filling of various container types? Be invited to the Groninger Showroom in Crailsheim where Marius Röme...

According to an evaluation of the WHO, medication errors cause at least one death every day and injure approximately 1.3 million people annually in the US alone.  Apart from harming patients, medication errors also drive up the costs for the health care system. Adverse drug events in US community hospitals cost more than 3,000 USD per incident on average and lead to a median increase of hospital l...

Glass is a strong material, but it can be sensitive if handled inadequately. SmartSkin’s Quantifeel pressure-sensing drones and SCHOTT’s glass analytics are powerful tools for identifying, localizing and verifying the root causes of breakage – helping to prevent unnecessary downtime and contributing to line optimization. Learn more about your ad choices. Visit megaphone.fm/adchoices

adaptiQ® offers proven SCHOTT vials in a modularized ready-to-use configuration. This session will focus on how our new packaging options can help you to increase manufacturing flexibility and improving TCO. All while ensuring patient safety. Learn more about your ad choices. Visit megaphone.fm/adchoices

COVID-19 has brought the mRNA era into existence. Biotechs that have been working on the technology for years are now ready for liftoff, with vaccines and therapeutics for a range of diseases from flu to cystic fibrosis.  But the technology comes with storage and transport limitations driven by the fragility of the lipid nanoparticles (LNPs) that function as mRNA delivery systems.  Deep cold tempe...

Protecting medication from undesired interactions with the surrounding environment and preserving their efficacy during shelf life is one of the most pressing challenges for the pharmaceutical industry. Specially developed inner coating solutions, such as SCHOTT TopLyo® and SCHOTT Type I plus® may fit to the specific needs in your drug development cycle. These functional coatings applied to the in...

Intravenous medications are a pivotal drug class that are used in many critical hospital treatments, for example on ICUs or in Operation Rooms. In these surroundings, the risk for medical errors, such as giving the wrong drug or the wrong dose can create a life-threatening situation for the patient. Especially in emergencies, the drug administration often has to be done very fast and, thus, time-c...

With more and more drugs shifting to a homecare setting, drug delivery devices and wearables are getting increasingly important. To ensure that pharmaceutical packaging meets the specific requirements of these devices, including functionality and ease-of-use, SCHOTT offers to co-create individualized containers made out of cyclic olefin copolymer (COC) with its customers. With SCHOTT TOPPAC® uniqu...

Sterile injectable drugs play a crucial role in the treatment of disease. All stakeholders in this industry have the inherent goal to make injectable drugs safe and effective. This includes an expectation that every lot be essentially free from visible particulates, and that manufacturers strive to minimize all particulate and foreign contamination. In this Webinar, we reveal how we reduce particl...

Sterility is the most critical parameter in ready-to-use packaging. As it depends not only on efficient processes but also on the involved packaging materials, choosing the appropriate sterilization technique is crucial to assure safe packaging components. Furthermore, sterile integrity of the primary packaging components has to be maintained during introduction and processing in an aseptic fill +...

Rejects and disruptions during pharmaceutical fill-and-finish operations are a main root cause for inefficient drug manufacturing. This is particularly relevant as the standard bulk filling process typically introduces cosmetic defects, such as scratches or abrasions, to the vials, leading to increased reject rates of the final product or even fatal events like glass breakage. EVERIC® strong & smo...

Pre-filled syringes made of high-quality Cyclic Olefin Copolymer (COC) have become a well-established alternative for administering drugs. Due to its properties and manufacturing process, COC is heavy metal and tungsten free and also exhibits low or no siliconization. However, the polymer also has a different E&L profile and a lower oxygen and gas barrier threshold than borosilicate glass, which i...

Standard pharmaceutical bulk fill-and-finish processes can introduce various damages to containers starting from cosmetic defects (as scratches or abrasions) to occasional glass breakage, leading to rejects and disruptions during manufacturing. We also cover an introduction to our EVERIC® strong module that shows how the inherent strength of a vial can be increased by optimizing the geometry with...

Advances in cryopreservation lead to new challenges in the field of pharmaceutical packaging. While it keeps the drug in a stable state, allows for longer shelf life, and ensures stability throughout the supply chain, manufacturers must plan for the unique challenges for vial-based container closure systems. In this session, our experts will share their study results in regards to container closur...

Fill & Finish is the core of the pharmaceutical industry. Any interference of the production process causes trouble in delivering the drug on time in a flexible and easy way. For this, it is indispensable to know what is happening on production lines and what impact they have on primary packaging. Data can be a valuable source of gaining insights on the performance of lines as well as a helpful re...

Cracking or breakage of primary packaging glass containers is an annoying incidence that can cause numerous unpleasant consequences, such as down time of fill & finish lines, vendor and customer complaints, right up to market recalls. In most cases, cracking or breakage of glass is the result of improper handling or processing and/or excessive mechanical loading. To better understand the mechanica...

This session addresses the market trend to individualizing primary packaging containers to the requirements of different drug formulations. Here, we show results (from studies of controlling delamination even) of stability studies of relevant biologic buffers and Water-for-injection with low-filling volumes in vials. A comparative study with standard vials will explain outstanding results. Learn m...