Retina Synthesis

Retina Synthesis

Retina Synthesis is a data-focused resource exploring therapies in development for retinal diseases.

Author

Retina Synthesis

Category

Education

Podcast website

retinasynthesis.com

Latest episode

Jul 7, 2026

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Episodes

Suprachoroidal Tyrosinase Therapy of Neovascular AMD 12.01.2023

We discuss the use of a suprachoroidal delivery system for delivery of tryrosinase kinase inhibitor for the treatment of neovascular AMD with Dr. Thomas Ciulla, Chief Development Officer, Chief Medical Officer, Clearside Biomedical.

KSI-301 (tarcocimab tedromer) therapy of Retinal Vein Occlusion 05.01.2023

We discuss a phase 2/3 trial employing tarcocimab reformer for branch and central vein occlusion with Michael Singer, MD, Clinical Professor University of Texas San Antonio Health Sciences Center.

The Efficacy of Avacincaptad Pegol in Treatment of Geographic Atrophy: Gather 1 & 2 Study Results 15.12.2022

We discuss the  use of intravitreal avacincaptad peg for the treatment of geographic atrophy in two randomized trials, Gather 1 and Gather 2 with Dr. Arshad Khanani, Sierra Eye Associates, Reno Nevada and Associate Clinical Professor University of Nevada Reno.

En Face OCT, Intermediate AMD, and Georgraphic Atrophy 08.12.2022

We discuss the role that en-face optical coherence tomography (OCT) can play in understanding the evolution of intermediate AMD and geographic atrophy with Dr. Philip Rosenfeld, Professor of Ophthalmology, Bascom Palmer Eye Institute and the University of Miami Miller School of Medicine.

Safety of Pegcetacoplan in the 24 month Derby and Oaks Studies 01.12.2022

We review the 24 month results of the Derby and Oaks trials, with emphasis on the safety of pegcetcoplan with Caroline Baumal, MD, Professor of Ophthalmology Tufts University School of Medicine and the New England Eye Center.

Predominantly Peripheral Lesions on Ultra-Wide field Imaging & Risk of DR Worsening Over Time 17.11.2022

Dr. Dennis Marcus, Clinical Professor of Ophthalmology, Medical College of Georgia at Augusta University discusses the value of ultra wide field imaging in assessing diabetic retinopathy worsening over time.

10 Year Retrospective Review of a PHP Device for Early Detection of Neovascular AMD 10.11.2022

Dr. Michael Elman of Elman Retina Group, Baltimore, Maryland, presents 10 year data demonstrating that Preferential Hyperacuity Perimetry (the Foresee Device) is a valuable tool in early detection of neovascular AMD.

Current Therapy for Venous Occlusive Disease and a Clinical Trial Involving Stem Cell Therapy for CRVO 27.10.2022

Dr. Susanna Park reviews current therapy of retinal branch and central vein occlusion and discusses a Phase I trial (the TRUST study) investigating the use of intravitreal autologous stem cells as a possible treatment for central vein occlusion.  Dr. Susanna Park, Professor of Ophthalmology, Roth Endowed Chair in Visual Science at the University of California, Davis

Senolytic Therapy for Diabetic Macular Edema and Neovascular AMD 20.10.2022

We discuss a novel mechanism of action for the treatment of diabetic macular edema and neovascular AMD with Phase I/II trial results Dr. Raj Maturi, Midwest Eye Institute, Indiana University School of Medicine.

Assessment of Geographic Atrophy Lesion Progression in the Phase 3 Oaks and Derby Trials 13.10.2022

We review lesion progression in the eighteen month data with Roger Goldberg, MD, MBA of Bay Area Retina Associates, Walnut Creek, California.

The Role of the Clinician in Promoting Innovation 06.10.2022

We discuss the role that clinicians can play in fostering innovation in the retinal pharmacotherapy space with Dr. Eliot Lazar.

The DAVIO Study: 12 Month Results 22.09.2022

We discuss the 12 month results of the Phase I Davio Trial of an innovative TKI agent for the sustained treatment of neovascular AMD with Dr. Rishi Singh, Professor of Ophthalmology, Cole Eye Insitute, President, Cleveland Cllinic-Martin Hospital, Stuart, Florida.

Treat and Extend Therapy of Diabetic Macular Edema 15.09.2022

We discuss treat and extend versus alternate dosing strategies to treat center involving diabetic macular edema with Dr. Varun Chaudhary, Chief of Ophthalmology, Hamilton Regional Eye Center and Professor, McMaster University.

Prophylactic IOP Lowering Measures in Anti-VEGF Injections: A Meta-Analysis 08.09.2022

We discuss the role of IOP pressure elevation following intravitreal anti-VEGF therapy with Parnian Arjmand, MD, MSC, FCSRS of the Toronto Retina Institute.

Real World Efficacy, Durability and Safety of Faricimab 01.09.2022

We discuss real world experience about faricimab with Dr. Carl Danzig of Pompano Beach, Florida.

New Treatments for Radiation Retinopathy 25.08.2022

We discuss new treatment options and clinical trials for radiation retinopathy with Prithvi Mruthyunjaya MD Professor of Ophthalmology, Stanford Medical School, Director of Ocular Oncology, Byers Eye Institute.

Gene Therapy of Inherited Retinal Diseases 18.08.2022

We discuss new developments in gene therapy for inherited retinal diseases with Sue Washer, President and CEO of AGTC.

RNA Anti Sense Therapy for Geographic Atrophy 11.08.2022

We discuss a novel strategy using RNA anti sense technology for treating geographic atrophy with Dr. Nik London,  San Diego, California.

18 Month Results of the Derby and Oaks Trials for Treatment of Geographic Atrophy 04.08.2022

We discuss the 18 month results of the Derby and Oaks trials of pegcetacoplan for treatment of geographic atrophy with Roger Goldberg, MD of Walnut Creek, California.

A Novel Retinal Sealant 28.07.2022

We discuss a new retinal sealant that may replace the need for tamponade with expansile gas or silicone oil with Dr. James Anthony Stefater.

New Developments in Imaging and Therapy of Sickle Cell Retinopathy 21.07.2022

We discuss how new developments in imaging and therapeutics have impacted the treatment of sickle cell retinopathy with Dr. Adrienne Scott, Professor of Ophthalmology at Johns Hopkins and the Wilmer Eye Institute.

High Dose (8mg) Aflibercept for Treatment of Neovascular AMD 07.07.2022

We discuss the results of a Phase II clinical trail studying the efficacy of high dose aflibercept (8mg) for treating neovascular AMD with Dr. David Brown of Retina Consultants of Texas in Houston.

New Developments in the Management of Choroidal Melanoma 30.06.2022

We discuss new developments in the diagnosis and therapy of choroidal melanoma with Dr. Paul Finger, Clinical Professor, NYU and Chair, Eye Cancer Foundation.

A Stem Cell Implant for the Treatment of Geographic Atrophy 23.06.2022

We discuss the two year results of a Phase I/II trial of a stem cell  implant for the treatment of geographic atrophy with Dr. Amir Kashani, Associate Professor, Wilmer Eye Institute.

DERBY and OAKS Results 16.06.2022

We discuss the one year results of the DERBY and OAKs studies treating geographic atrophy with Dr. David Lally,  Assistant Professor University of Massachusetts and Tufts University.

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