Research To Practice | Oncology Videos

Featuring perspectives from Drs Alexander Spira and Helena Yu, including the following topics: Introduction  What is an antibody-drug conjugate? (0:00) "HER2-Positive" Non-Small Cell Lung Cancer (NSCLC)  Case: A woman in her mid 50s with HER2 insertion in exon 20 — Dr Yu (8:42) Targeting HER3 in NSCLC  Case: A man in his early 60s with lung cancer with an EGFR mutation — Dr Yu (25:23) TROP2-Direct...

Featuring perspectives from Dr S Vincent Rajkumar, including the following topics: Introduction: Requiem for Belantamab Mafodotin? Dawn of a New Era (0:00) Case: A man in his early 70s with multiregimen-refractory multiple myeloma (MM) receives idecabtagene vicleucel with Grade 1 cytokine release syndrome and persistent cytopenias — Jesús G Berdeja, MD (16:12) Case: A man in his mid 60s with multi...

Featuring a slide presentation and related discussion from Dr Omid Hamid, including the following topics: Current evolution in the care of patients with metastatic melanoma (0:00) Novel immunotherapeutic strategies for patients with untreated metastatic melanoma (1:47) Efficacy and safety of novel agents and combination treatments for patients with previously treated metastatic melanoma (16:28) Fu...

Featuring an interview with Dr Omid Hamid, including the following topics: First-line treatment of metastatic melanoma (0:00) Triplet therapy for patients with BRAF-mutated metastatic melanoma (7:27) Case: A man in his mid 60s with previously untreated BRAF wild-type metastatic melanoma (15:44) Novel therapeutic strategies for patients with newly diagnosed melanoma (21:02) Immunotherapy strategies...

Featuring a slide presentation and related discussion from Dr Eric Sherman, including the following topics: Incidence and mortality of thyroid cancer and the thyroid cancer treatment pyramid (0:00) Available and emerging data with targeted therapies for thyroid cancer (9:01) Optimal genomic screening and selection of treatment for medullary thyroid cancer (26:58) CME information and select publica...

Featuring an interview with Dr Eric Sherman, including the following topics: Changes in the incidence, mortality, and management of thyroid cancer in the past 20 years (0:00) Clinical presentation and histologic characteristics of thyroid cancer; genomic alterations associated with each histology (5:55) Initial management of thyroid cancer; current role of surgery and radioactive iodine in treatme...

Featuring perspectives from Prof Karim Fizazi and Prof Stéphane Oudard, including the following topics: Introduction: Journal Club — Karim Fizazi, MD, PhD and Stéphane Oudard, MD, PhD (0:00) Case: A man in his late 50s with Gleason 7 prostate cancer after prostatectomy/radiation therapy/androgen deprivation therapy (ADT) experiences biochemical recurrence 2 years later (PSA 0.5; doubling time 9 mo...

Featuring a slide presentation and related discussion from Dr Jeffrey Zonder, including the following topics: Overview of amyloid light chain (AL) amyloidosis (0:00) Case: An African American man in his late 70s with transthyretin amyloidosis (8:39) Staging and prognosis of AL amyloidosis (14:11) Evolution of the amyloidosis treatment paradigm (26:39) Case: A woman in her late 70s with relapsed la...

Featuring an interview with Dr Jeffrey Zonder, including the following topics: Biology and symptomology of primary amyloidosis (0:00) Staging and prognosis for patients with amyloid light chain (AL) amyloidosis (10:21) Supportive care for patients with advanced disease (16:25) Current amyloidosis treatment paradigm (21:49) Monoclonal antibody therapy for patients with AL amyloidosis (31:38) CME in...

Featuring perspectives from Dr Daniel Pollyea, including the following topics: Introduction (0:00) Acute Myeloid Leukemia (AML), 2014 to 2022 (3:35) Defining AML versus Myelodysplastic Syndromes (6:06) Case: A man in his early 80s presenting with cytopenias and AML (8:56) Oral Decitabine/Cedazuridine (18:15) Management of Cytopenias with HMA (Hypomethylating Agent)/Venetoclax: Drug-Drug Interactio...

Featuring perspectives from Dr Paul Richardson, including the following topics: Introduction (0:00) Case: A man in his early 60s with newly diagnosed Stage II standard-risk multiple myeloma — Ranju Gupta, MD (29:31) Case: A woman in her early 70s with Stage IIIA multiple myeloma who receives lenalidomide/bortezomib/dexamethasone → autologous stem cell transplant (ASCT) and discontinues maintenance...

Featuring a slide presentation and related discussion from Dr Ruben Mesa, including the following topics: Efficacy and safety of FDA-approved JAK inhibitors for the management of myelofibrosis (MF) (0:00) Emerging JAK inhibitors under Phase III evaluation for MF (6:59) Current guidelines and strategies for managing MF (13:53) Emerging data with novel agents and strategies for MF (17:31) Splenic re...

Featuring an interview with Dr Ruben Mesa, including the following topics: Managing myelofibrosis (MF) before the availability of ruxolitinib (0:00) Pathobiology and mutational profile of MF (7:33) Matching treatments to individual patients with MF (13:25) Case: A man in his early 70s with MF and worsening anemia (17:13) Case: A man in his late 60s initially diagnosed with polycythemia vera now wi...

Featuring perspectives from Drs Ursula Matulonis and Debra Richardson, including the following topics: PROLOGUE: Antibody-Drug Conjugates Across Oncology (0:00) Antibody-Drug Conjugates in Ovarian Cancer: Mirvetuximab Soravtansine (10:03) Antibody-Drug Conjugates in Ovarian Cancer: Upifitamab Rilsodotin (29:09) Tumor Treating Fields (41:35) PARP Inhibitor Update (47:29) CME information and select...

Featuring a slide presentation and related discussion from Dr Toni Choueiri, including the following topics: Evolution in the management of renal cell carcinoma (RCC) (0:00) Adjuvant therapy for intermediate- or high-risk RCC (1:52) Front-line therapy for patients with metastatic RCC (8:39) New agents for the treatment of relapsed or refractory RCC (16:24) Mechanism of action and efficacy of HIF2-...

Featuring an interview with Dr Toni Choueiri, including the following topics: Case: A woman in her early 70s with a large kidney tumor and multiple pulmonary nodules (0:00) Case: A woman in her early 60s diagnosed with metastatic clear cell renal cell carcinoma (RCC) (12:52) Approach to adjuvant treatment for RCC (16:14) Examining differences between PD-1 and PD-L1 inhibitors (20:09) Management of...

Current Paradigm and Future Directions for Immunotherapy in the Treatment of Metastatic Non-Small Cell Lung Cancer — Faculty Presentation 2: Anti-PD-1 and PD-L1 Monotherapy for NSCLC — Dr Stephen Liu CME information and select publications

Current Paradigm and Future Directions for Immunotherapy in the Treatment of Metastatic Non-Small Cell Lung Cancer — Faculty Presentation 1: Current Treatment Landscape for Non-Small Cell Lung Cancer (NSCLC) — Dr John Heymach CME information and select publications

Featuring perspectives from Drs John Heymach and Stephen Liu, including the following topics: Introduction (0:00) Current Immunotherapy-Based Strategies for Non-Small Cell Lung Cancer (NSCLC) (9:29) Future Directions in the Management of NSCLC (37:09) CME information and select publications

Featuring perspectives from Dr Lisa Carey, including the following topics: Introduction: Journal Club with Lisa A Carey, MD, ScM (0:00) Case: A woman in her late 70s presents with triple-positive breast cancer and a suspicious mass in the liver — Zanetta S Lamar, MD (8:51) Case: A woman in her mid 40s with ER/PR-negative, HER2-positive metastatic breast cancer with a complete response to paclitaxe...

Featuring a slide presentation and related discussion from Professor Arndt Vogel, including the following topics: Advances in first-line treatment for patients with advanced hepatocellular carcinoma (HCC) (0:00) Outcomes of Phase III clinical trials evaluating single-agent immunotherapy as initial treatment for advanced HCC (4:19) Immune checkpoint inhibitors as second-line treatment for recurrent...

Featuring an interview with Professor Arndt Vogel, including the following topics: Case: A man in his early 40s with hepatitis B virus infection and hepatocellular carcinoma (HCC) with Child-Pugh C, ALBI 3 cirrhosis (0:00) Case: A man in his late 60s with metastatic HCC with Child-Pugh A, ALBI 2 cirrhosis (7:54) Case: A man in his early 70s with rheumatoid arthritis diagnosed with Barcelona Clinic...

Featuring an interview with Dr Eytan Stein, including the following topics: Practical considerations for using venetoclax/HMA (hypomethylating agent) combinations in the management of acute myeloid leukemia (AML) (0:00) Approach to transplant for older patients with AML (10:33) Potential availability of magrolimab and sabatolimab in clinical practice (13:04) ASH 2022 preview: Investigational thera...

Featuring a slide presentation and related discussion from Dr Eytan Stein, including the following topics: Historical paradigms for treating newly diagnosed acute myeloid leukemia (AML) (0:00) Long-term findings and emerging results with venetoclax-based therapies for newly diagnosed and relapsed/refractory (R/R) AML (1:19) Efficacy and tolerability of oral decitabine/cedazuridine for patients wit...

Proceedings from a daylong symposium hosted in partnership with Florida Cancer Specialists, featuring key clinical presentations and papers in melanoma. Featuring perspectives from Prof Georgina Long, including the following topics: Neoadjuvant and Adjuvant Therapy for Melanoma (0:00) Update on the Management of Metastatic Melanoma (19:23) CME information and select publications