NP Z

Pearls and Prep

******* There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.”Be the second on Patreon:https://www.patreon.com/c/PearlsandPrepPearls and Prep: Psychiatric Case Studies is the go-to podcast for psychiatric nurse practitioner students, psych residents, clinicians, and anyone fascinated by the human mind. Whether you’re prepping for boards, sharpening your diagnostic skills, or just curious about what psychiatry looks like behind the scenes, this show delivers clinical gold in every episode.🎯 What You’ll Learn:Each episode walks you through real-...

Be sure to visit the podcast's website and support the creator: pearlsandprep.captivate.fm

Author

NP Z

Category

Education

Podcast website

pearlsandprep.captivate.fm

Latest episode

Nov 6, 2026

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Episodes

Understanding the Mechanisms of Weight Gain in Psychiatric Patients 24.02.2026

The discussion centers on the intricacies of weight gain associated with certain psychiatric medications, particularly focusing on the case of a mock patient named Johnny, a 30-year-old welder who has experienced significant weight gain while stabilized on Olanzapine, also known as Zyprexa. We delve into the three primary pathways that contribute to medication-induced weight gain: histamine antago...

Six Shocking Mental Health Pearls That Will Transform Your Clinical Practice 17.02.2026

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This podcast episode delves into six pivotal insights that possess the potential to radically transform our understanding of psychiatric practice and patient care. One particularly alarming statistic reveals that 4% of untreated...

Bonus Episode: Can You Answer These 3 Second Generation Antipsychotic Questions? 13.02.2026

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This podcast episode delves into the intricate considerations surrounding the selection of second-generation antipsychotics, particularly in patients presenting with metabolic syndrome and an expressed desire to transition from...

The Nuances of Treating ADHD in Patients with Bipolar Disorder 10.02.2026

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This discussion centers on the intricate relationship between bipolar disorder and attention-deficit/hyperactivity disorder (ADHD), particularly focusing on the challenges of prescribing stimulants to patients with these co-occu...

Serotonin Syndrome: High-Yield Pearls Every Clinician Should Know 03.02.2026

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This episode elucidates a case study that exemplifies the clinical presentation of serotonin syndrome, a condition characterized by a constellation of symptoms including altered mental status, muscle rigidity, and hyperthermia....

Optimizing Antidepressant Therapy: To Increase, Switch or Augment? 27.01.2026

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep The principal focus of this discourse centers upon the concept of partial response to treatment with antidepressants, a phenomenon characterized by a reduction in depression rating scores of less than 50%. Throughout our dialogu...

Bonus Episode: One Detail That Can Derail Your Diagnosis 25.01.2026

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This podcast episode presents a compelling exploration of a mock case study concerning a 35-year-old woman who has experienced significant psychological distress following her recent job loss. The salient point of the discussion...

4 High-Yield Cannabis Pearls Every Mental Health Provider Should Know 20.01.2026

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep The central theme of today’s discourse revolves around the intricate relationship between cannabis use and its implications on mental health, particularly emphasizing the significance of understanding the endocannabinoid system....

Exploring Remeron: Eight Things Every Practitioner Should Know 13.01.2026

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep The salient point of this podcast episode centers on the multifaceted advantages and unique pharmacological profile of Remeron, particularly in the treatment of depression. We commence with a clinical vignette involving a patien...

Vitamin D & Mental Health: Pearls Every Clinician Should Know 06.01.2026

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep The discourse presented herein meticulously elucidates the paramount significance of vitamin D, positing it as a pivotal hormone rather than merely a dietary vitamin. We expound upon the profound implications of vitamin D on neu...

In the Ring: Lexapro vs. Prozac - A Comprehensive Analysis 30.12.2025

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep In this podcast episode, we meticulously dissect the pharmacological distinctions between Lexapro and Prozac, with the objective of determining the most suitable medication for our hypothetical patient, Benny. Benny, a 32-year-o...

PEARL OF THE WEEK: A DSM Diagnosis That Can Reduce Life Expectancy by an Average of 7 Years 23.12.2025

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep Welcome back to a BONUS episode of Pearls and Prep! This episode dives deep into one of the most under-discussed and urgent realities of ADHD: the strikingly higher risk of premature death across the lifespan—and what actually d...

Stocking Stuffer Bonus: High-Yield Pearls on Bipolar Activation, SSRIs, and Mood Stabilizers 22.12.2025

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep 🎙️ Episode Description Antidepressants are foundational in psychiatry — and also one of the easiest ways to accidentally destabilize mood if bipolar risk isn’t recognized early. In this episode of Pearls and Prep , we break down...

T-Tests and Tummy Aches: How to Read a Research Study Like a Pro 16.12.2025

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep Are you a psychiatric mental health nurse practitioner (PMHNP) student struggling to make sense of p-values, odds ratios, or confidence intervals? Do you wish someone would just explain evidence-based practice in mental health u...

Pearl of the Week: What Is the Only Transdermal Antidepressant? 09.12.2025

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This week’s Pearl of the Week dives into one of psychiatry’s most overlooked breakthroughs: the only transdermal antidepressant the FDA has ever approved. Why did this one medication earn a category all its own? What makes its d...

Navigating Acute Dystonias: Clinical Insights and Management 02.12.2025

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This podcast episode elucidates the complexities surrounding dystonia, a neurological movement disorder characterized by involuntary muscle contractions leading to abnormal postures and movements. We commence by exploring a mock...

Pearl of the Week: The Bipolar Blind Spot 25.11.2025

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep The salient point of this podcast episode is the astonishing statistic that the average delay in accurately diagnosing bipolar disorder is nine years following a patient's initial depressive episode. This revelation underscores...

Bonus Episode: Board Bombs: 3 High-Yield Psychiatric Questions to Prepare You for Your Board Exam 21.11.2025

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep 🔥 Bonus Board Bombs: 3 High-Yield Questions Every PMHNP Must Master Before the Exam Get ready to level up your PMHNP board prep with three ultra-high-yield “Board Bombs” designed to sharpen your clinical reasoning, boost exam c...

Exploring the Diagnostic Challenges in Anxiety: Jean Luc's Journey 18.11.2025

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep The primary focus of this podcast episode revolves around the intricate relationship between caffeine consumption and its potential psychological ramifications, particularly as illustrated through the case of a mock patient name...

PEARL OF THE WEEK: What is the only DSM diagnosis that requires a rating of symptoms? 11.11.2025

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep Think you know your DSM-5-TR inside and out? In this Pearl of the Week episode, we’re asking a question that stumps even seasoned clinicians: Which DSM-5-TR diagnosis actually requires a validated rating scale to confirm it? Is...

Exploring Mixed Features in Major Depressive Disorder: The Case of Gus 04.11.2025

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep Today, we delve into the intricate case of mock patient, Gus, a 23-year-old male grappling with debilitating depression and psychotic symptoms. His experience includes a notable history of Wellbutrin use, which initially seemed...

Board Bombs - 3 Critical Questions to Prepare you For Boards and Empower your Practice 28.10.2025

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This podcast episode delves into the intricacies of pharmacological preparations for the NP board exams, specifically focusing on the implications of amitriptyline and its adverse effects. We meticulously analyze a clinical vign...

Exploring the Nuances of ADHD vs. Bipolar Disorder in Outpatient Care 21.10.2025

Differentiating ADHD from Bipolar Disorder: A Case Study with Dale In this episode of 'Pearls and Prep,' host NPZ presents a detailed case study of a mock patient named Dale, exploring symptoms that could be indicative of ADHD or bipolar disorder. The session focuses on analyzing Dale’s history, behavior, and psychiatric background to understand the complexity of his condition. Key educational poi...

Board Bombs: 3 Great Practice Psychiatric Nurse Practitioner Board Prep Questions 14.10.2025

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep 🎧 Episode Title: 3 Board Bombs Every Psych NP Needs to Master: Illness Anxiety, Lamotrigine, and MAOI Protocols Episode Summary: Whether you're days from testing or deep in the trenches of your clinical prep, this episode deliv...

From Volcanoes to Nightmares: A Deep Dive on Prazosin 07.10.2025

There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep Managing PTSD and Nightmares: An In-Depth Case Study In this episode of Pearls and Prep, the focus is on a mock patient named Marcus who has been suffering from PTSD-related nightmares after falling into a non-active volcano yea...

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