NP Z
Pearls and Prep
******* There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.”Be the second on Patreon:https://www.patreon.com/c/PearlsandPrepPearls and Prep: Psychiatric Case Studies is the go-to podcast for psychiatric nurse practitioner students, psych residents, clinicians, and anyone fascinated by the human mind. Whether you’re prepping for boards, sharpening your diagnostic skills, or just curious about what psychiatry looks like behind the scenes, this show delivers clinical gold in every episode.🎯 What You’ll Learn:Each episode walks you through real-...
Author
NP Z
Category
Podcast website
Latest episode
Jul 7, 2026
Where to listen?
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Episodes
This Mood Stabilizer Problem Can Mimic a Whole New Disorder 27.05.2026 15:30
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep We dive into a real head-scratcher today, tackling the case of (MOCK PATIENT) Henrietta, a 42-year-old woman who’s found herself in a bit of a pickle with some gambli...
Exploring the Nuances of Depression: Specifiers and Their Implications 26.05.2026 23:00
Today, we delve into the intricate subject of major depressive disorder (MDD) and its myriad specifiers, underscoring the essential point that depression is not monolithic; rather, it presents in diverse forms that necessitate precise understanding for effective treatment. As we navigate the complexities of this disorder, it becomes evident that recognizing specific features—such as mixed features...
Why Luvox Hits Different: Sigma Receptors, OCD, and the Anxious Brain 25.05.2026 20:13
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep Today, we're diving into the world of Luvox, an SSRI that you probably haven’t prescribed before, but trust me, it’s got some serious potential. We’re breaking down w...
How to Choose the RIGHT Neurotransmitter Target 24.05.2026 26:49
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep Today, we’re diving into the big bad three neurotransmitters: serotonin, dopamine, and norepinephrine. Forget what you think you know about these guys—serotonin isn’t...
Jane’s Mold Meltdown: OCD or Delusional Disorder? 23.05.2026 22:03
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep Today, we're diving into the nitty-gritty of diagnosing a tricky case: is it a delusional disorder or OCD? Picture this: you've got Jane, our mock patient, who’s conv...
Don’t Panic During the Cross-Taper: 4 Antipsychotic Switching Pearls 22.05.2026 26:36
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep Today, we're diving into the nitty-gritty of antipsychotic switching, and trust me, it’s not as straightforward as flipping a light switch. We’ve got six pearls lined...
🧠💣 BOARD BOMBS: The OCD Gold Standard Almost Nobody Actually Gets — And It Delays Treatment for YEARS. 21.05.2026 17:58
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep Today’s episode is all about diagnosing and treating OCD, specifically through the case of Terri, our imaginary patient who’s wrestling with some pretty gnarly intrus...
These TWO Details Separate OCD from GAD Almost Every Time 20.05.2026 17:03
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep Today, we’re diving into the wild world of OCD, using our mock patient Terri as a case study. She’s been battling some seriously gnarly intrusive thoughts and rituals...
MDD with Mixed Features: What Do You Reach for When SSRIs Stop Making Sense? 19.05.2026 26:05
Today, we're diving into the wild world of Major Depressive Disorder with mixed features—yeah, it's as tricky as it sounds! We’re chatting about how this gray area in mental health can really throw a wrench in the works for both patients and clinicians. Did you know that around one in five folks with MDD has these mixed features? That's a number that gets my attention! We're breaking down the chal...
Have We Been Treating Only Half of Schizophrenia? Vraylar, D3 Dopamine, and the Symptoms That Quietly Ruin Functioning 18.05.2026 28:08
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep We're diving deep into schizophrenia today, and let me tell ya, we’re shining a big ol’ spotlight on the often-overlooked negative symptoms. You know how everyone’s q...
Board Bombs: The KEY Schizophrenia Symptoms Most Students Underestimate 17.05.2026 11:37
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep Today, we're diving deep into the world of schizophrenia, specifically zeroing in on those pesky negative symptoms that can seriously cramp a person’s style. We’ve go...
Borderline Personality Disorder and Persistent Depression Can Look IDENTICAL. Until You Ask the Right Questions. 16.05.2026 31:14
https://www.patreon.com/c/PearlsandPrep — Access Full Clinical Library here!!! We’re diving into a gnarly showdown between persistent depressive disorder and borderline personality disorder today. Like, if you’ve ever been stumped by the similarities between the two, you’re not alone—trust me, it can be a real brain teaser! We’ll explore a mock case study featuring Mara, a 34-year-old who’s been f...
Trazodone Isn’t Just a Sleep Med… So What Is It Really? 15.05.2026 29:21
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep We're diving deep into Trazodone today, and let me tell you, it's way more than just a sleep aid. If you get a grip on Trazodone, you’re basically unlocking the door...
Gabapentin: The Duct Tape of Psychiatry 14.05.2026 22:09
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep Gabapentin is the star of today’s show, and let me tell you, it’s a medication that’s both fascinating and misunderstood. We dive into why it’s probably underprescrib...
The Most Common Anxiety Disorder May Never Walk Into Your Clinic — But We Still Need to Recognize It 13.05.2026 17:43
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep Today, we're diving into the surprising world of anxiety disorders and uncovering the fact that the most common one out there is actually a specific phobia. Yep, you...
The Most Dangerous Window in Psychiatry. Can you guess what it is? 12.05.2026 16:39
The principal focus of this podcast episode revolves around the exceedingly high suicide risk observed during the initial week following psychiatric hospital discharge. In this discussion, we delve into an illuminating multiple-choice question that challenges our understanding of psychiatric vulnerabilities. The episode underscores the alarming statistic that, within the first three months post-di...
Inside the Ring 🥊: Lamictal vs. Seroquel — A Deep-Dive into 2 of The Bipolar Depression Heavyweights. 11.05.2026 23:28
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep Today, we’re diving into the heavyweight showdown between Seroquel and Lamictal to see which medication packs a better punch for bipolar depression. Spoiler alert: Se...
1 in 7 of Your Patients Will Experience This Hidden Dental Disaster! And 80% have No Clue! 10.05.2026 11:58
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep We've got a juicy nugget for you today: one in seven patients starting on antidepressants might develop bruxism, which is basically the fancy term for grinding your t...
Board Bomb Bonus Episode: This One Wrong Medication Choice Can Blow Up Your Treatment Plan 09.05.2026 14:27
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep Today, we’re diving deep into the tricky world of pharmacotherapy—specifically, figuring out the least appropriate meds for our buddy(mock patinet) Lenny, who’s juggl...
Board Bomb 💣: Would You Miss This Depakote Red Flag? 08.05.2026 8:20
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep Today, we're diving into the wild world of pharmacokinetics with a case that's got more twists than a soap opera. Our star (MOCK) patient, Desiree, is dealing with bi...
Board Bomb Bonus Episode: This Long Acting Injectable (LAI) Question Trips Up Clinicians All the Time 07.05.2026 11:24
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep We're diving into a super relevant topic today about long-acting injectables, specifically Invega Sustenna, and trust me, it's packed with pearls to keep you sharp! W...
Board Bomb: This Urine Drug Screen Changes Everything—Now What? 06.05.2026 20:03
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Patients know the difference. Know the WHY! Join our clinical library today on PATREON! 👉 https://www.patreon.com/PearlsandPrep We’re diving into a wild case today with our girl Bonnie, who's all sunshine and rainbows—except for those pesky positive drug screen results that have us scratching...
Catch the Curveball: Can you spot the problem in this mock medication regimen? 05.05.2026 13:12
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep This podcast episode elucidates the intricacies surrounding the case of a mock patient named Larry, who presents with persistent morning fatigue despite an improvement in his depressive symptoms. The primary focus of our discuss...
PEARL DROP: With SGAs, How Often Is Metformin Actually Used? 04.05.2026 5:25
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep Alright, folks, let’s dive into a real eye-opener about metformin and its under-prescription among patients on second-generation antipsychotics. Believe it or not, only about 2 to 3% of these patients are actually getting the he...
Psychiatric Board Bomb: Can You Nail this Diagnosis? It is Trickier Than You Think! 01.05.2026 26:17
There are two kinds of clinicians—the ones who follow algorithms, and the ones who understand the “why.” Be the second on Patreon: 👉 https://www.patreon.com/PearlsandPrep Today, we’re diving deep into the wild world of mood disorders, specifically focusing on the juicy details around bipolar disorder and its sneaky symptoms. You know, the kind of stuff that can trip you up if you’re not paying at...
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